WJP · Methyl (3R,6Z,10E,14E)-3,7,11,15,19-pentamethylicosa-6, 10,14,18-tetraen-1-yl dihydrogen diphosphate

Binding sites

WJP in 3 structures; the first of them:

• 6WLW · The vo region of human V-ATPase in state 1 (focused refinement) · WJP R905 · binds ILE147, SER534, MET537, LYS538, VAL541, PHE583, LYS593, SER607 and 7 more
• 6WM2 · Human V-ATPase in state 1 with sidk and ADP · WJP R907 · binds SER534, MET537, LYS538, VAL541, PHE583, LYS593, SER607, LEU608 and 8 more
• 7KHR · Cryo-EM structure of bafilomycin A1-bound intact V-ATPase from bovine brain · WJP a901 · binds SER535, LYS539, VAL542, PHE584, ILE591, LYS594, SER608, LEU609 and 7 more

Residues it binds most

PHE 3, ILE 3, LEU 3, LYS 3, SER 3, VAL 3, ALA 3, THR 3, MET 2 (residue and the binding sites it lines).

Found with

• BMA · beta-D-mannopyranose
• GLC · alpha-D-glucopyranose
• MAN · alpha-D-mannopyranose
• NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose
• ADP · Adenosine-5'-diphosphate
• CLR · Cholesterol
• PTY · Phosphatidylethanolamine
• WJS · (2~{S})-2-$l^{4}-azanyl-3-[[(2~{R})-3-octadecanoyloxy-2-oxidanyl-propoxy]-oxidanyl-oxidanylidene-$l^{6}-phosphanyl]oxy-propanoic acid
• WSS · Tri(methyl)-[2-[[(2~{R})-2-[(~{Z})-octadec-9-enoyl]oxy-3-[(~{E})-1-oxidanylideneoctadec-9-enoxy]propoxy]-oxidanyl-phosphoryl]oxyethyl]azanium
• BGC · beta-D-glucopyranose
• GAL · beta-D-galactopyranose
• NGA · 2-acetamido-2-deoxy-beta-D-galactopyranose