UniProt P27338
Amine oxidase [flavin-containing] B (P27338)
Amine oxidase [flavin-containing] B (UniProt P27338), EC 1.4.3.4: 101 experimental structures and 1 predicted model on GenesisL1, 14 ligands bound, 125 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P27338
- Protein
- Amine oxidase [flavin-containing] B
- EC
- 1.4.3.4
- Experimental structures
- 101
- Predicted models
- 1
- Ligands
- 14
- Pockets
- 125 · 10 records with a druggable one
Structures
102 records of P27338 in the MolNFT archive: 101 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1GOS | Human Monoamine Oxidase B | x-ray diffraction | A, B | — | — |
| 1GOS | Human monoamine oxidase B | x-ray diffraction | A, B | — | — |
| 1OJ9 | Human monoamine oxidase B in complex with 1,4-diphenyl-2-butene | x-ray diffraction | A, B | — | — |
| 1OJ9 | Human monoamine oxidase B in complex with 1,4-diphenyl-2-butene | x-ray diffraction | A, B | — | — |
| 1OJA | Human monoamine oxidase B in complex with isatin | x-ray diffraction | A, B | — | — |
| 1OJA | Human monoamine oxidase B in complex with isatin | x-ray diffraction | A, B | — | — |
| 1OJC | HUMAN MONOAMINE OXIDASE B IN COMPLEX WITH N-(2-aminoethyl)-p-chlorobenzamide | x-ray diffraction | A, B | — | — |
| 1OJC | Human monoamine oxidase B in complex with N-(2-aminoethyl)-P-chlorobenzamide | x-ray diffraction | A, B | — | — |
| 1OJD | HUMAN MONOAMINE OXIDASE B IN COMPLEX WITH Lauryldimethylamine-N-oxide (LDAO) | x-ray diffraction | A, B, C, D, E, F, G, H, I, L | — | — |
| 1OJD | Human monoamine oxidase B in complex with lauryldimethylamine-N-oxide (ldao) | x-ray diffraction | A, B, C, D, E, F, G, H, I, L | — | — |
| 1S2Q | Crystal structure of MAOB in complex with N-propargyl-1(R)-aminoindan (Rasagiline) | x-ray diffraction | A, B | — | — |
| 1S2Q | Crystal structure of maob in complex with N-propargyl-1(R)-aminoindan (rasagiline) | x-ray diffraction | A, B | — | — |
| 1S2Y | Crystal structure of MAOB in complex with N-propargyl-1(S)-aminoindan | x-ray diffraction | A, B | — | — |
| 1S2Y | Crystal structure of maob in complex with N-propargyl-1(S)- aminoindan | x-ray diffraction | A, B | — | — |
| 1S3B | Crystal structure of MAOB in complex with N-methyl-N-propargyl-1(R)-aminoindan | x-ray diffraction | A, B | — | — |
| 1S3B | Crystal structure of maob in complex with N-methyl-N- propargyl-1(R)-aminoindan | x-ray diffraction | A, B | — | — |
| 1S3E | Crystal structure of MAOB in complex with 6-hydroxy-N-propargyl-1(R)-aminoindan | x-ray diffraction | A, B | — | — |
| 1S3E | Crystal structure of maob in complex with 6-hydroxy-N- propargyl-1(R)-aminoindan | x-ray diffraction | A, B | — | — |
| 2BK3 | Human Monoamine Oxidase B in complex with Farnesol | x-ray diffraction | A, B | — | — |
| 2BK3 | Human monoamine oxidase B in complex with farnesol | x-ray diffraction | A, B | — | — |
| 2BK4 | Human Monoamine Oxidase B: I199F mutant in complex with rasagiline | x-ray diffraction | A, B | — | — |
| 2BK4 | Human monoamine oxidase B: I199F mutant in complex with rasagiline | x-ray diffraction | A, B | — | — |
| 2BK5 | Human Monoamine Oxidase B: I199F mutant in complex with isatin | x-ray diffraction | A, B | — | — |
| 2BK5 | Human monoamine oxidase B: I199F mutant in complex with isatin | x-ray diffraction | A, B | — | — |
| 2BYB | Human Monoamine Oxidase B in complex with Deprenyl | x-ray diffraction | A, B | — | — |
| 2BYB | Human monoamine oxidase B in complex with deprenyl | x-ray diffraction | A, B | — | — |
| 2C64 | MAO inhibition by rasagiline analogues | x-ray diffraction | A, B | — | — |
| 2C64 | Mao inhibition by rasagiline analogues | x-ray diffraction | A, B | — | — |
| 2C65 | MAO inhibition by rasagiline analogues | x-ray diffraction | A, B | — | — |
| 2C65 | Mao inhibition by rasagiline analogues | x-ray diffraction | A, B | — | — |
| 2C66 | MAO inhibition by rasagiline analogues | x-ray diffraction | A, B | — | — |
| 2C66 | Mao inhibition by rasagiline analogues | x-ray diffraction | A, B | — | — |
| 2C67 | MAO inhibition by rasagiline analogues | x-ray diffraction | A, B | — | — |
| 2C67 | Mao inhibition by rasagiline analogues | x-ray diffraction | A, B | — | — |
| 2C70 | Functional Role of the Aromatic Cage in Human Monoamine Oxidase B: Structures and Catalytic… | x-ray diffraction | A, B | — | — |
| 2C70 | Functional role of the aromatic cage in human monoamine oxidase B: structures and catalytic… | x-ray diffraction | A, B | — | — |
| 2C72 | Functional Role of the Aromatic Cage in Human Monoamine Oxidase B: Structures and Catalytic… | x-ray diffraction | A, B | — | — |
| 2C72 | Functional role of the aromatic cage in human monoamine oxidase B: structures and catalytic… | x-ray diffraction | A, B | — | — |
| 2C73 | Functional Role of the Aromatic Cage in Human Monoamine Oxidase B: Structures and Catalytic… | x-ray diffraction | A, B | — | — |
| 2C73 | Functional role of the aromatic cage in human monoamine oxidase B: structures and catalytic… | x-ray diffraction | A, B | — | — |
| 2C75 | Functional Role of the Aromatic Cage in Human Monoamine Oxidase B: Structures and Catalytic… | x-ray diffraction | A, B | — | — |
| 2C75 | Functional role of the aromatic cage in human monoamine oxidase B: structures and catalytic… | x-ray diffraction | A, B | — | — |
| 2C76 | Functional Role of the Aromatic Cage in Human Monoamine Oxidase B: Structures and Catalytic… | x-ray diffraction | A, B | — | — |
| 2C76 | Functional role of the aromatic cage in human monoamine oxidase B: structures and catalytic… | x-ray diffraction | A, B | — | — |
| 2V5Z | Structure of human MAO B in complex with the selective inhibitor safinamide | x-ray diffraction | A, B | — | — |
| 2V5Z | Structure of human mao B in complex with the selective inhibitor safinamide | x-ray diffraction | A, B | — | — |
| 2V60 | Structure of human MAO B in complex with the selective inhibitor 7-(3… | x-ray diffraction | A, B | — | — |
| 2V60 | Structure of human mao B in complex with the selective inhibitor… | x-ray diffraction | A, B | — | — |
| 2V61 | Structure of human MAO B in complex with the selective inhibitor 7-(3… | x-ray diffraction | A, B | — | — |
| 2V61 | Structure of human mao B in complex with the selective inhibitor… | x-ray diffraction | A, B | — | — |
| 2VRL | Structure of human MAO B in complex with benzylhydrazine | x-ray diffraction | A, B | — | — |
| 2VRL | Structure of human mao B in complex with benzylhydrazine | x-ray diffraction | A, B | — | — |
| 2VRM | Structure of human MAO B in complex with phenyethylhydrazine | x-ray diffraction | A, B | — | — |
| 2VRM | Structure of human mao B in complex with phenyethylhydrazine | x-ray diffraction | A, B | — | — |
| 2VZ2 | Human MAO B in complex with mofegiline | x-ray diffraction | A, B | — | — |
| 2VZ2 | Human mao B in complex with mofegiline | x-ray diffraction | A, B | — | — |
| 2XCG | Tranylcypromine-inhibited human monoamine oxidase B in complex with 2… | x-ray diffraction | A, B | — | — |
| 2XCG | Tranylcypromine-inhibited human monoamine oxidase B in complex with 2… | x-ray diffraction | A, B | — | — |
| 2XFN | Human monoamine oxidase B in complex with 2-(2-benzofuranyl)-2- imidazoline | x-ray diffraction | A, B | — | — |
| 2XFN | Human monoamine oxidase B in complex with 2-(2-benzofuranyl)-2- imidazoline | x-ray diffraction | A, B | — | — |
42 records more on the page itself.
Ligands
- FAD · Flavin-adenine dinucleotide · in 23 records
- C15 · N-dodecyl-N,N-dimethyl-3-ammonio-1-propanesulfonate · in 21 records
- 5IH · 3,4-dimethyl-7-[[(3~{S})-piperidin-3-yl]methoxy]chromen-2-one · in 2 records
- 5IK · 4-(hydroxymethyl)-7-[[4-[[methyl-(phenylmethyl) amino]methyl]phenyl]methoxy]chromen-2-one · in 2 records
- E8Z · ~{N}-(3,4-dimethylphenyl)-4-oxidanylidene-chromene-3-carboxamide · in 2 records
- E92 · ~{N}-(3-chlorophenyl)-4-oxidanylidene-chromene-3-carboxamide · in 2 records
- E98 · ~{N}-(3-fluorophenyl)-4-oxidanylidene-chromene-3-carboxamide · in 2 records
- F2M · (~{E})-~{N}-(furan-2-ylmethyl)-~{N}-methyl-prop-1-en-1-amine · in 2 records
- K6Q · 4-[(~{E})-2-(4-fluorophenyl)ethenyl]-1-[(~{E})-prop-1-enyl]piperidine · in 2 records
- K72 · 1-[(~{E})-prop-1-enyl]-4-[(~{E})-2-[4-(trifluoromethyl)phenyl]ethenyl]piperidine · in 2 records
- K8B · 4-[2-(4-propan-2-ylphenyl)ethyl]-1-[(~{E})-prop-1-enyl]piperidine · in 2 records
- PJW · benzo[b][1]benziodole · in 2 records
- SKB · (E)-3-phenyl-1-(3-(trifluoromethyl)phenyl)prop-2-en-1-one · in 2 records
- SK5 · (E)-3-phenyl-1-(4-(trifluoromethyl)phenyl)prop-2-en-1-one · in 1 record
Experiment against prediction
- 1S3B chain B against the predicted model P27338: TM-score 1.00, RMSD 0.50 Å
- 1S3B chain B against the predicted model P27338: TM-score 1.00, RMSD 0.50 Å
- 2VRM chain B against the predicted model P27338: TM-score 1.00, RMSD 0.51 Å
- 2VRM chain B against the predicted model P27338: TM-score 1.00, RMSD 0.51 Å
- 1OJA chain B against the predicted model P27338: TM-score 1.00, RMSD 0.51 Å
- 1OJA chain B against the predicted model P27338: TM-score 1.00, RMSD 0.51 Å
- 2C67 chain B against the predicted model P27338: TM-score 1.00, RMSD 0.51 Å
- 2C67 chain B against the predicted model P27338: TM-score 1.00, RMSD 0.51 Å
- 1OJD chain G against the predicted model P27338: TM-score 1.00, RMSD 0.51 Å
- 1OJD chain G against the predicted model P27338: TM-score 1.00, RMSD 0.51 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.