GL1X · GenesisL1 explorer

Ligand · FA8

FA8 · [[(2R,3S,4S)-5-[(4AS)-7,8-dimethyl-2,4-dioxo-4A,5-dihydrobenzo[g]pteridin-10-yl]-2,3,4-trihydroxy-pentoxy]-hydroxy-phosphoryl] [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methyl hydrogen phosphate

FA8, [[(2R,3S,4S)-5-[(4AS)-7,8-dimethyl-2,4-dioxo-4A,5-dihydrobenzo[g]pteridin-10-yl]-2,3,4-trihydroxy-pentoxy]-hydroxy-phosphoryl] [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methyl hydrogen phosphate (C27 H35 N9 O15…

Component
FA8
Formula
C27 H35 N9 O15 P2
Class
ligand
Structures
1
PDB entries
1

Binding sites

FA8 in 1 structure; the first of them:

  • 7XW8 · Crystal structure of Lysine Specific Demethylase 1 (LSD1) with TAK-418 distomer… · FA8 A904 · binds ILE284, GLY285, SER286, GLY287, VAL288, SER289, GLY290, LEU307 and 33 more

Residues it binds most

GLY 1, VAL 1, ALA 1, LEU 1, ARG 1, SER 1, THR 1, GLU 1, TRP 1, ILE 1 (residue and the binding sites it lines).

Found with

  • I00 · ~{N}-(oxan-4-yl)-5-(3-oxidanylidenepropyl)thiophene-3-carboxamide
  • MG · Magnesium ion
  • GOL · Glycerol

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