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Ligand · RAS

RAS · (1R)-N-(prop-2-en-1-yl)-2,3-dihydro-1H-inden-1-amine

RAS, (1R)-N-(prop-2-en-1-yl)-2,3-dihydro-1H-inden-1-amine (C12 H15 N, 173.2 g/mol), in the MolNFT structures on GenesisL1: bound in 6 records (3 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most…

Component
RAS
Formula
C12 H15 N
Class
ligand
Structures
6
PDB entries
3

Binding sites

RAS in 6 structures; the first of them:

  • 1S2Q · Crystal structure of MAOB in complex with N-propargyl-1(R)-aminoindan (Rasagiline) · RAS A601 · binds LEU171, CYS172, ILE198, ILE199, GLN206, TYR326, PHE343, TYR398 and 1 more
  • 2BK4 · Human Monoamine Oxidase B: I199F mutant in complex with rasagiline · RAS A601 · binds TYR60, LEU171, CYS172, ILE198, PHE199, GLN206, TYR326, PHE343 and 2 more
  • 2XFQ · Rasagiline-inhibited human monoamine oxidase B in complex with 2-(2… · RAS A601 · binds TYR60, LEU171, CYS172, ILE198, ILE199, GLN206, TYR326, PHE343 and 2 more
  • 1S2Q · Crystal structure of maob in complex with N-propargyl-1(R)-aminoindan (rasagiline) · RAS A601 · binds LEU171, CYS172, ILE198, ILE199, GLN206, TYR326, PHE343, TYR398 and 1 more
  • 2BK4 · Human monoamine oxidase B: I199F mutant in complex with rasagiline · RAS A601 · binds TYR60, LEU171, CYS172, ILE198, PHE199, GLN206, TYR326, PHE343 and 2 more
  • 2XFQ · Rasagiline-inhibited human monoamine oxidase B in complex with 2-(2… · RAS A601 · binds TYR60, LEU171, CYS172, ILE198, ILE199, GLN206, TYR326, PHE343 and 2 more

Residues it binds most

TYR 12, ILE 12, PHE 12, CYS 12, GLN 12, LEU 12 (residue and the binding sites it lines).

Found with

  • FAD · Flavin-adenine dinucleotide
  • C15 · N-dodecyl-N,N-dimethyl-3-ammonio-1-propanesulfonate
  • XCG · 2-(2-benzofuranyl)-2-imidazoline

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