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Ligand · FOF

FOF · (2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-ol

FOF, (2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-ol (C15 H26 O, 222.4 g/mol), in the MolNFT structures on GenesisL1: bound in 7 records (4 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and…

Component
FOF
Formula
C15 H26 O
Class
ligand
Structures
7
PDB entries
4

Binding sites

FOF in 7 structures; the first of them:

  • 6DEW · Structure of human COQ9 protein with bound isoprene. · FOF A304 · binds VAL150, ASN154, ARG189, LEU204, LEU207, MET208, SER216, LEU217 and 6 more
  • 6EIZ · A de novo designed hexameric coiled coil CC-Hex2 with farnesol bound in the channel. · FOF F101 · binds LEU7, ILE10, LEU14, ILE17, LEU14, LEU7, LEU14, LEU7 and 7 more
  • 6NUX · CD1a-lipid binary complex · FOF A301 · binds PHE10, VAL12, TRP14, PHE70, THR74, SER77, VAL98, GLY100 and 3 more
  • 8FKB · X-ray crystal structure of CYP124A1 from Mycobacterium Marinum bound to Farnesol · FOF A505 · binds ASN93, ILE94, VAL95, ASP98, GLN99, THR100, PHE107, ILE111 and 10 more
  • 6DEW · Structure of human COQ9 protein with bound isoprene. · FOF A304 · binds VAL150, ASN154, ARG189, LEU204, LEU207, MET208, LEU217, LEU219 and 5 more
  • 6EIZ · A de novo designed hexameric coiled coil cc-HEX2 with farnesol bound in the channel. · FOF F101 · binds LEU14, LEU14, LEU14, ILE17
  • 6NUX · CD1A-lipid binary complex · FOF A301 · binds PHE10, VAL12, TRP14, PHE70, THR74, SER77, VAL98, GLY100 and 3 more

Residues it binds most

LEU 7, ILE 3, VAL 5, PHE 3, THR 3, ASN 3, MET 3, GLU 3, SER 3, ARG 2 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion
  • 64Z · Geraniol
  • FOH · (2Z,6Z)-3,7,11-trimethyldodeca-2,6,10-trien-1-ol
  • N1S · (2Z,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-ol
  • EDO · 1,2-ethanediol
  • ACE · Acetyl group
  • HEM · Protoporphyrin IX containing Fe
  • PEG · Di(hydroxyethyl)ether
  • PGE · Triethylene glycol

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