UniProt P25655
General negative regulator of transcription subunit 1 (P25655)
General negative regulator of transcription subunit 1 (UniProt P25655): 10 experimental structures and 1 predicted model on GenesisL1, 18 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P25655
- Protein
- General negative regulator of transcription subunit 1
- Experimental structures
- 10
- Predicted models
- 1
- Pockets
- 18 · 1 record with a druggable one
Structures
11 records of P25655 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4B89 | MIF4G domain of the yeast Not1 | x-ray diffraction | A | — | — |
| 4B89 | MIF4G domain of the yeast NOT1 | x-ray diffraction | A | — | — |
| 4B8A | Structure of yeast NOT1 MIF4G domain co-crystallized with CAF1 | x-ray diffraction | A | — | — |
| 4B8A | Structure of yeast NOT1 MIF4G domain co-crystallized with CAF1 | x-ray diffraction | A | — | — |
| 4B8B | N-Terminal domain of the yeast Not1 | x-ray diffraction | A, B | — | — |
| 4B8B | N-terminal domain of the yeast NOT1 | x-ray diffraction | A, B | — | — |
| 4B8C | nuclease module of the yeast Ccr4-Not complex | x-ray diffraction | B, G, H, I | — | — |
| 4B8C | Nuclease module of the yeast CCR4-not complex | x-ray diffraction | B, G, H, I | — | — |
| 4CV5 | yeast NOT1 CN9BD-CAF40 complex | x-ray diffraction | A, C | — | — |
| 4CV5 | Yeast NOT1 CN9BD-CAF40 complex | x-ray diffraction | A, C | — | — |
| P25655 | AlphaFold monomer V2.0 prediction for general negative regulator of transcription subunit 1 (P25655) | predicted | A | — | 18 (best 0.72) |
Experiment against prediction
- 4B89 chain A against the predicted model P25655: TM-score 0.99, RMSD 0.55 Å
- 4B89 chain A against the predicted model P25655: TM-score 0.99, RMSD 0.55 Å
- 4B8A chain A against the predicted model P25655: TM-score 0.99, RMSD 0.64 Å
- 4B8A chain A against the predicted model P25655: TM-score 0.99, RMSD 0.64 Å
- 4B8C chain B against the predicted model P25655: TM-score 0.99, RMSD 0.78 Å
- 4B8C chain B against the predicted model P25655: TM-score 0.99, RMSD 0.78 Å
- 4CV5 chain A against the predicted model P25655: TM-score 0.94, RMSD 1.35 Å
- 4CV5 chain A against the predicted model P25655: TM-score 0.94, RMSD 1.35 Å
- 4B8B chain A against the predicted model P25655: TM-score 0.94, RMSD 2.20 Å
- 4B8B chain A against the predicted model P25655: TM-score 0.94, RMSD 2.20 Å
Elsewhere
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