UniProt P25286
V-type proton ATPase 116 kDa subunit a isoform 1 (P25286)
V-type proton ATPase 116 kDa subunit a isoform 1 (UniProt P25286): 20 experimental structures on GenesisL1, 8 ligands bound, 37 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P25286
- Protein
- V-type proton ATPase 116 kDa subunit a isoform 1
- Experimental structures
- 20
- Predicted models
- 0
- Ligands
- 8
- Pockets
- 37 · 9 records with a druggable one
Structures
20 records of P25286 in the MolNFT archive: 20 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6VQ6 | Mammalian V-ATPase from rat brain - composite model of rotational state 1 bound to ADP and SidK… | electron microscopy | a | — | 4 (best 0.84) |
| 6VQ6 | Mammalian V-ATPase from rat brain - composite model of rotational state 1 bound to ADP and sidk… | electron microscopy | a | — | — |
| 6VQ7 | Mammalian V-ATPase from rat brain - composite model of rotational state 2 bound to ADP and sidk… | electron microscopy | a | — | — |
| 6VQ8 | Mammalian V-ATPase from rat brain - composite model of rotational state 3 bound to ADP and sidk… | electron microscopy | a | — | — |
| 6VQC | Mammalian V-ATPase from rat brain membrane-embedded vo region rotational state 1 (from focused… | electron microscopy | a | — | — |
| 6VQG | Mammalian V-ATPase from rat brain membrane-embedded vo region rotational state 2 (from focused… | electron microscopy | a | — | — |
| 6VQH | Mammalian V-ATPase from rat brain membrane-embedded Vo region rotational state 3 (from focused… | electron microscopy | a | — | 6 (best 0.84) |
| 6VQH | Mammalian V-ATPase from rat brain membrane-embedded vo region rotational state 3 (from focused… | electron microscopy | a | — | — |
| 6VQI | Mammalian V-ATPase from rat brain collar and peripheral stalks rotational state 1 (from focused… | electron microscopy | a | — | — |
| 6VQJ | Mammalian V-ATPase from rat brain collar and peripheral stalks rotational state 2 (from focused… | electron microscopy | a | — | 6 (best 0.77) |
| 6VQJ | Mammalian V-ATPase from rat brain collar and peripheral stalks rotational state 2 (from focused… | electron microscopy | a | — | — |
| 6VQK | Mammalian V-ATPase from rat brain collar and peripheral stalks rotational state 3 (from focused… | electron microscopy | a | — | — |
| 7UZF | Rat Kidney V-ATPase with SidK, State 1 | electron microscopy | a | — | 3 (best 0.81) |
| 7UZG | Rat Kidney V-ATPase lacking subunit H, with SidK and NCOA7B, State 1 | electron microscopy | a | — | 2 (best 0.82) |
| 7UZI | Rat Kidney V-ATPase lacking subunit H, with SidK and NCOA7B, State 2 | electron microscopy | a | — | 2 (best 0.82) |
| 9B8Q | Synaptic Vesicle V-ATPase with synaptophysin and SidK, State 3, peripheral stalks | electron microscopy | a | — | 8 (best 0.77) |
| 9BRB | Synaptic Vesicle V-ATPase with synaptophysin and SidK, State 1 | electron microscopy | a | — | — |
| 9BRC | Synaptic Vesicle V-ATPase with synaptophysin and SidK, State 2 | electron microscopy | a | — | 1 (best 0.80) |
| 9BRD | Synaptic Vesicle V-ATPase with synaptophysin and SidK, State 3 | electron microscopy | a | NAG, BMA, MAN, GLC, PC1, PTY | 5 (best 0.82) |
| P25286 | AlphaFold monomer V2.0 prediction for V-type proton ATPase 116 kda subunit A1 (P25286) | — | — | — |
Ligands
- BMA · beta-D-mannopyranose · in 1 record
- GLC · alpha-D-glucopyranose · in 1 record
- LP3 · (7R)-4,7-dihydroxy-N,N,N-trimethyl-10-oxo-3,5,9-trioxa-4-phosphaheptacosan-1-aminium 4-oxide · in 1 record
- MAN · alpha-D-mannopyranose · in 1 record
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 1 record
- PC1 · 1,2-diacyl-sn-glycero-3-phosphocholine · in 1 record
- PTY · Phosphatidylethanolamine · in 1 record
- WJP · Methyl (3R,6Z,10E,14E)-3,7,11,15,19-pentamethylicosa-6, 10,14,18-tetraen-1-yl dihydrogen diphosphate · in 1 record
Elsewhere
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