UniProt P24021
Nuclease S1 (P24021)
Nuclease S1 (UniProt P24021), EC 3.1.30.1: 15 experimental structures on GenesisL1, 11 ligands bound, 4 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P24021
- Protein
- Nuclease S1
- EC
- 3.1.30.1
- Experimental structures
- 15
- Predicted models
- 0
- Ligands
- 11
- Pockets
- 4 · 2 records with a druggable one
Structures
15 records of P24021 in the MolNFT archive: 15 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5FB9 | S1 nuclease from Aspergillus oryzae with unoccupied active site | x-ray diffraction | A, B | ZN, NAG, NA | 1 (best 0.73) |
| 5FB9 | S1 nuclease from aspergillus oryzae with unoccupied active site | x-ray diffraction | A, B | — | — |
| 5FBA | S1 nuclease from aspergillus oryzae in complex with phosphate | x-ray diffraction | A | — | — |
| 5FBB | S1 nuclease from Aspergillus oryzae in complex with phosphate and adenosine 5'-monophosphate | x-ray diffraction | A, B | — | — |
| 5FBB | S1 nuclease from Aspergillus oryzae in complex with phosphate and adenosine 5'-monophosphate | x-ray diffraction | A, B | ZN, NAG, PO4, AMP, NA, CA | — |
| 5FBB | S1 nuclease from aspergillus oryzae in complex with phosphate and adenosine 5'-monophosphate | x-ray diffraction | A, B | — | — |
| 5FBC | S1 nuclease from Aspergillus oryzae in complex with 2'-deoxyadenosine-5'-thio-monophosphate… | x-ray diffraction | A | ZN, NAG, AS | — |
| 5FBC | S1 nuclease from aspergillus oryzae in complex with 2'-deoxyadenosine- 5'-thio-monophosphate… | x-ray diffraction | A | — | — |
| 5FBD | S1 nuclease from Aspergillus oryzae in complex with phosphate and 2'-deoxycytidine | x-ray diffraction | A | ZN, NAG, PO4, DCZ | — |
| 5FBD | S1 nuclease from aspergillus oryzae in complex with phosphate and 2'- deoxycytidine | x-ray diffraction | A | — | — |
| 5FBF | S1 nuclease from Aspergillus oryzae in complex with two molecules of… | x-ray diffraction | A | ZN, NAG, DCM, NA | — |
| 5FBF | S1 nuclease from aspergillus oryzae in complex with two molecules of… | x-ray diffraction | A | — | — |
| 5FBG | S1 nuclease from Aspergillus oryzae, mutant D65N, in complex with phosphate, 2'-deoxycytidine and… | x-ray diffraction | A, B | ZN, NAG, PO4, DCZ, GNG | 3 (best 0.70) |
| 5FBG | S1 nuclease from aspergillus oryzae, mutant D65N, in complex with phosphate, 2'-deoxycytidine and… | x-ray diffraction | A, B | — | — |
| P24021 | AlphaFold monomer V2.0 prediction for nuclease S1 (P24021) | — | — | — |
Ligands
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 6 records
- ZN · Zinc ion · in 6 records
- NA · Sodium ion · in 3 records
- PO4 · Phosphate ion · in 3 records
- DCZ · 2'-deoxycytidine · in 2 records
- AMP · Adenosine monophosphate · in 1 record
- AS · 2-deoxy-adenosine -5'-thio-monophosphate · in 1 record
- CA · Calcium ion · in 1 record
- DCM · 2'-deoxycytidine-5'-monophosphate · in 1 record
- ETE · 2-{2-[2-2-(methoxy-ethoxy)-ethoxy]-ethoxy}-ethanol · in 1 record
- GNG · 2'-deoxy-guanosine · in 1 record
Elsewhere
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