DCM · 2'-deoxycytidine-5'-monophosphate

Binding sites

DCM in 19 structures; the first of them:

• 5FBF · S1 nuclease from Aspergillus oryzae in complex with two molecules of… · DCM A601 · binds LYS68, TYR69, PHE81, ASP83, HIS145, ALA151, GLY152, ASN154 and 1 more
• 5JP9 · Crystal Structure of cytidine monophosphate hydroxymethylase MilA with dCMP · DCM A401 · binds ARG31, TYR72, TYR104, VAL153, CYS155, MET174, ARG175, ALA176 and 8 more
• 5MQL · Crystal structure of dCK mutant C3S in complex with masitinib and UDP · DCM B302 · binds ILE30, LYS34, GLU53, VAL55, TRP58, LEU82, MET85, TYR86 and 9 more
• 5MQT · Crystal structure of dCK mutant C3S in complex with imatinib and UDP · DCM B303 · binds ILE30, ALA31, LYS34, GLU53, VAL55, TRP58, LEU82, MET85 and 13 more
• 5WRN · Human thymidylate synthase complexed with dCMP · DCM B400 · binds CYS195, HIS196, GLN214, ARG215, SER216, GLY217, ASP218, GLY222 and 6 more
• 5XPD · Sugar transporter of AtSWEET13 in inward-facing state with a substrate analog · DCM A301 · binds SER20, LEU23, PHE24, ASN54, TRP58, ILE75, ASN76, SER142 and 6 more
• 6A9A · Ternary complex crystal structure of dCH with dCMP and THF · DCM A302 · binds LYS28, TYR96, PHE146, SER148, THR149, MET167, ARG168, SER169 and 6 more
• 6SQY · Mouse dCTPase in complex with dCMP · DCM A202 · binds HIS38, PHE41, TRP47, HIS51, GLU63, ASP98, ILE101, TYR102 and 1 more
• 7P9T · Crystal structure of CD73 in complex with dCMP in the open form · DCM A604 · binds ARG354, ASN390, GLY392, GLY393, ARG395, PHE417, GLY447, PHE500 and 1 more
• 5MQL · Crystal structure of dck mutant C3S in complex with masitinib and udp · DCM B302 · binds ILE30, LYS34, GLU53, VAL55, TRP58, LEU82, MET85, TYR86 and 9 more
• 5MQT · Crystal structure of dck mutant C3S in complex with imatinib and udp · DCM B303 · binds ILE30, ALA31, LYS34, GLU53, VAL55, TRP58, LEU82, MET85 and 10 more
• 5W0U · Crystal structure of mbp fused activation-induced cytidine deaminase (aid) in complex… · DCM B2002 · binds ARG1025, THR1027, ASN1051, SER1085, PRO1086, CYS1087, TYR1114
• 5XPD · Sugar transporter of ATSWEET13 in inward-facing state with a substrate analog · DCM A301 · binds SER20, LEU23, PHE24, TRP58, ILE75, ASN76, ASN176, TRP180 and 3 more
• 5ZRG · M. smegmatis antimutator protein MUTT2 in complex with dcmp · DCM A201 · binds VAL6, ARG22, GLU33, LEU34, LEU73, LEU79, ALA115, ASP116
• 6A46 · Structure of TREX2 in complex with a nucleotide (dcmp) · DCM A303 · binds LEU15, GLU16, ALA17, GLY19, LEU20, LYS73, ALA74, ILE77 and 4 more
• 6A9A · Ternary complex crystal structure of dch with dcmp and thf · DCM A302 · binds LYS28, TYR96, SER148, MET167, ARG168, SER169, ASN170, ASP171 and 5 more
• 6SQY · Mouse dctpase in complex with dcmp · DCM A202 · binds HIS38, PHE41, TRP47, HIS51, GLU63, ASP98, ILE101, TYR102 and 1 more
• 7FH4 · Chlorovirus pbcv-1 bi-functional DCMP/DCTP deaminase bi-dcd · DCM A201 · binds ASP21, ASN23, THR24, VAL26, ASN43, LYS58, LYS61, TYR62 and 10 more
• 7P9T · Crystal structure of CD73 in complex with dcmp in the open form · DCM A604 · binds ARG354, ASN390, GLY392, GLY393, ARG395, PHE417, GLY447, PHE500 and 1 more

Residues it binds most

ARG 23, TYR 30, ASP 31, HIS 21, GLU 15, PHE 20, ASN 19, GLY 16, TRP 16, LYS 18 (residue and the binding sites it lines).

Found with

• MG · Magnesium ion
• ZN · Zinc ion
• UDP · Uridine-5'-diphosphate
• CA · Calcium ion
• G65 · Masitinib
• STI · 4-(4-methyl-piperazin-1-ylmethyl)-N-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide
• IOD · Iodide ion
• DCP · 2'-deoxycytidine-5'-triphosphate
• THG · (6S)-5,6,7,8-tetrahydrofolate
• NA · Sodium ion
• NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose
• GOL · Glycerol