Ligand · THG
THG · (6S)-5,6,7,8-tetrahydrofolate
THG, (6S)-5,6,7,8-tetrahydrofolate (C19 H23 N7 O6, 445.4 g/mol), in the MolNFT structures on GenesisL1: bound in 7 records (6 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found…
- Component
- THG
- Formula
- C19 H23 N7 O6
- Class
- ligand
- Structures
- 7
- PDB entries
- 6
Binding sites
THG in 7 structures; the first of them:
- 5T7O · Crystal structure of Trypanosoma cruzi Dihydrofolate Reductase-Thymidylate Synthase in… · THG A702 · binds VAL26, VAL27, ALA28, ASP48, MET49, PHE52, ARG53, THR80 and 9 more
- 5X1L · Vanillate/3-O-methylgallate O-demethylase, LigM, tetrahydrofolate complex form · THG B501 · binds GLN57, MET61, ASN81, ALA91, LYS92, GLN93, ASP106, GLY107 and 11 more
- 6A9A · Ternary complex crystal structure of dCH with dCMP and THF · THG A303 · binds LYS28, ASN53, TYR56, ARG59, GLU60, PRO79, ILE81, TRP82 and 7 more
- 6MT8 · E. coli DHFR complex modeled with two ligand states · THG A208 · binds ILE5, ALA6, ALA7, MET16, MET20, ASP27, LEU28, TRP30 and 9 more
- 7VG5 · 10,5-methenyltetrahydrofolate cyclohydrolase from Methylobacterium extorquens AM1 with… · THG A301 · binds GLY22, GLY23, GLY24, ASP79, PHE83, ALA114, PRO118, ASN164 and 6 more
- 7WI9 · The THF-II riboswitch bound to THF and soaking with SeUrea · THG V101 · binds U17, A21, C22, G25, C43, U44, A45
- 7VG5 · 10,5-methenyltetrahydrofolate cyclohydrolase from methylobacterium extorquens AM1 with… · THG A301 · binds GLY22, GLY23, GLY24, ASP79, PHE83, ALA114, PRO118, ASN164 and 5 more
Residues it binds most
PHE 12, VAL 11, GLY 7, ASP 11, ASN 7, ILE 8, PRO 10, ALA 11, ARG 6, THR 5 (residue and the binding sites it lines).
Found with
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