Ligand · COA
COA · Coenzyme A
COA, Coenzyme A (C21 H36 N7 O16 P3 S, 767.5 g/mol), in the MolNFT structures on GenesisL1: bound in 311 records (266 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with it.
- Component
- COA
- Formula
- C21 H36 N7 O16 P3 S
- Class
- ligand
- Structures
- 311
- PDB entries
- 266
Binding sites
COA in 311 structures; the first of them:
- 5EBV · Crystal structure of acetyltransferase Eis from Mycobacterium tuberculosis in complex… · COA A501 · binds VAL87, ARG92, ARG93, ARG94, GLY95, LEU96, LEU97, ARG98 and 2 more
- 5EC4 · Crystal structure of acetyltransferase Eis from Mycobacterium tuberculosis in complex… · COA A501 · binds SER83, PHE84, VAL85, ALA86, VAL87, ARG92, ARG93, ARG94 and 9 more
- 5EGJ · The structural and biochemical characterization of acyl-coa hydrolase mutant Asn28Ala… · COA A200 · binds THR60, ALA61, SER62, GLY88, THR89, SER90, SER91, THR117 and 4 more
- 5EO2 · Structural and biochemical characterization of the hypothetical protein SAV2348 from… · COA A201 · binds HIS22, MET23, ASP25, TYR28, TYR66, LEU67, SER68, GLU69 and 10 more
- 5F48 · Crystal structure of an aminoglycoside acetyltransferase meta-AAC0020 from an uncultured… · COA B201 · binds VAL34, PHE35, LEU92, ALA93, VAL94, GLN99, ARG100, GLN101 and 9 more
- 5F49 · Crystal structure of an aminoglycoside acetyltransferase meta-AAC0020 from an uncultured… · COA A201 · binds VAL34, PHE35, LEU92, ALA93, VAL94, GLN99, ARG100, GLN101 and 13 more
- 5FRD · Structure of a thermophilic esterase · COA A1257 · binds GLY115, ALA116, ARG117, LEU118, ARG119, VAL120, LEU121, MET142 and 6 more
- 5G1F · Crystal structure of the 6-carboxyhexanoate-CoA ligase (BioW)from Bacillus subtilis in… · COA B301 · binds GLU66, ARG13, SER15, PHE60, ARG123, LYS142, ARG145
- 5GI9 · Crystal Structure of Drosophila melanogaster Dopamine N-Acetyltransferase in Ternary… · COA A301 · binds ASP46, GLU47, PRO48, LEU146, SER147, VAL148, ARG153, GLY154 and 10 more
- 5HBR · Ca. Korarchaeum cryptofilum dinucleotide forming Acetyl-coenzyme A synthetase 1 in… · COA A501 · binds VAL16, GLY17, SER19, LYS24, ILE25, ILE45, ASN46, PRO47 and 13 more
- 5HH0 · Crystal structure of human Naa60 in complex with CoA · COA A201 · binds TRP33, SER100, LEU101, GLY102, VAL103, ARG108, LYS109, HIS110 and 9 more
- 5HH1 · Crystal structure of human Naa60 mutant - F34A in complex with CoA · COA A201 · binds TRP33, SER100, LEU101, GLY102, VAL103, ARG108, LYS109, HIS110 and 9 more
- 5ICW · Crystal structure of human NatF (hNaa60) homodimer bound to Coenzyme A · COA A201 · binds PHE34, LEU101, GLY102, VAL103, ARG108, LYS109, HIS110, GLY111 and 9 more
- 5IV0 · Crystal structure of Eis from Mycobacterium tuberculosis in complex with sulfonamide… · COA A501 · binds SER83, PHE84, VAL85, VAL87, ARG92, ARG93, ARG94, GLY95 and 8 more
- 5JFM · Crystal structure of Rhodopseudomonas palustris propionaldehyde dehydrogenase with bound… · COA B601 · binds ILE194, THR195, PRO196, THR197, THR198, ASN199, SER221, PRO222 and 13 more
- 5KF8 · X-ray structure of a glucosamine N-Acetyltransferase from Clostridium acetobutylicum in… · COA A406 · binds PHE189, TRP193, ILE253, GLY254, ILE255, ARG260, LYS261, GLN262 and 7 more
- 5KF9 · X-ray structure of a glucosamine N-Acetyltransferase from Clostridium acetobutylicum in… · COA A403 · binds PHE189, TRP193, GLY254, ILE255, ARG260, LYS261, GLN262, GLY263 and 3 more
- 5KP2 · Beta-ketoacyl-ACP synthase III -2 (FabH2) (C113A) from Vibrio Cholerae cocrystallized… · COA B401 · binds ASP30, THR31, TRP35, ARG39, THR40, ARG152, PHE214, GLY216 and 6 more
- 5KTD · FdhC with bound products: Coenzyme A and dTDP-3-amino-3,6-dideoxy-d-glucose · COA A203 · binds LEU33, ILE37, TRP97, ILE98, LEU99, LYS103, LYS105, TYR106 and 10 more
- 5LKU · Crystal structure of the p300 acetyltransferase catalytic core with coenzyme A. · COA A1705 · binds LEU1398, ASP1399, SER1400, ARG1410, THR1411, TYR1414, TRP1436, CYS1438 and 10 more
- 5MY0 · Ks-mat di-domain of mouse fas with malonyl-CoA · COA A900 · binds GLN502, HIS580, K5L581, ALA622, CYS642, ASN644, THR648, THR650 and 4 more
- 5T7E · Crystal structure of Streptomyces hygroscopicus Bialaphos Resistance (BAR) protein in… · COA A800 · binds TYR28, VAL34, VAL91, TYR92, VAL93, HIS97, GLN98, ARG99 and 13 more
- 5VXC · Crystal Structure Analysis of human CLYBL in complex with free CoASH · COA A401 · binds LEU49, TYR50, VAL51, LYS57, LYS58, LYS61, GLY77, ARG107 and 4 more
- 5XXR · Crystal structure of selenomethionine labelled RIBT from Bacillus subtilis · COA A200 · binds PHE19, MSE20, PRO21, ILE71, SER72, VAL73, ARG78, HIS79 and 10 more
Residues it binds most
ARG 602, GLY 559, LEU 562, ALA 514, LYS 510, PHE 545, SER 494, VAL 433, ILE 444, THR 398 (residue and the binding sites it lines).
Found with
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