UniProt P18177
Toxin B (P18177)
Toxin B (UniProt P18177), EC 3.4.22.-: 33 experimental structures on GenesisL1, 9 ligands bound, 24 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P18177
- Protein
- Toxin B
- EC
- 3.4.22.-
- Experimental structures
- 33
- Predicted models
- 0
- Ligands
- 9
- Pockets
- 24 · 3 records with a druggable one
Structures
33 records of P18177 in the MolNFT archive: 33 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2BVL | Crystal structure of the catalytic domain of toxin B from Clostridium difficile in complex with… | x-ray diffraction | A | — | — |
| 2BVL | Crystal structure of the catalytic domain of toxin B from clostridium difficile in complex with… | x-ray diffraction | A | — | — |
| 2BVM | Crystal structure of the catalytic domain of toxin B from Clostridium difficile in complex with… | x-ray diffraction | A | — | — |
| 2BVM | Crystal structure of the catalytic domain of toxin B from clostridium difficile in complex with… | x-ray diffraction | A | — | — |
| 4NC2 | Crystal structure of TcdB-B1 bound to B39 VHH | x-ray diffraction | A | — | — |
| 4NC2 | Crystal structure of tcdb-B1 bound to B39 vhh | x-ray diffraction | A | — | — |
| 4NP4 | Clostridium difficile toxin B CROP domain in complex with FAB domains of neutralizing antibody… | x-ray diffraction | A | — | — |
| 4NP4 | Clostridium difficile toxin B crop domain in complex with Fab domains of neutralizing antibody… | x-ray diffraction | A | — | — |
| 5UQM | Clostridium difficile toxin B (tcdb) glucosyltransferase domain in complex with U2F | x-ray diffraction | A | MN, U2F, SO4 | — |
| 5UQN | Clostridium difficile toxin B (tcdb) glucosyltransferase domain in complex with U2F | x-ray diffraction | A | MN, U2F, SO4 | — |
| 5UQT | Clostridium difficile Toxin B (TcdB) glucosyltransferase domain co-crystallized with apigenin | x-ray diffraction | A, B | MN, AGI | 9 (best 0.73) |
| 5UQT | Clostridium difficile toxin B (tcdb) glucosyltransferase domain co- crystallized with apigenin | x-ray diffraction | A, B | MN, AGI | — |
| 6AR6 | Clostridioides difficile toxinB with DLD-4 darpin | electron microscopy | A | — | — |
| 6AR6 | Clostridioides difficile toxinb with dld-4 darpin | electron microscopy | A | — | — |
| 6OQ8 | Structure of the gtd domain of clostridium difficile toxin B in complex with vhh 7F | x-ray diffraction | A, B | — | — |
| 7LOU | Crystal structure of clostridium difficile toxin B (tcdb) glucosyltransferase in complex with udp… | x-ray diffraction | A, B | UDP, IFM, MN | — |
| 7LOV | Crystal structure of clostridium difficile toxin B (tcdb) glucosyltransferase in complex with udp… | x-ray diffraction | A, B | NOY, UDP, MN | — |
| 7ML7 | Structural basis for CSPG4 as a receptor for tcdb and a therapeutic target in clostridioides… | electron microscopy | A | ZN | — |
| 7N8X | Partial C. difficile TcdB and CSPG4 fragment | electron microscopy | A | — | 12 (best 0.82) |
| 7N8X | Partial C. difficile tcdb and CSPG4 fragment | electron microscopy | A | — | — |
| 7N95 | State 1 of tcdb and FZD2 at PH5 | electron microscopy | A | — | — |
| 7N97 | State 2 of TcdB and FZD2 at pH5 | electron microscopy | A | — | — |
| 7N97 | State 2 of tcdb and FZD2 at PH5 | electron microscopy | A | — | — |
| 7N9Q | State 3 of tcdb and FZD2 at PH5 | electron microscopy | A | — | — |
| 7N9R | State 4 of tcdb and FZD2 at PH5 | electron microscopy | A | — | — |
| 7N9S | Tcdb and frizzled-2 crd complex | electron microscopy | A | — | — |
| 7N9Y | Full-length tcdb and CSPG4 (401-560) complex | electron microscopy | A | — | — |
| 7S0Y | Structures of TcdB in complex with Cdc42 | x-ray diffraction | A | MN, UDP, SO4, MG | 3 (best 0.86) |
| 7S0Y | Structures of tcdb in complex with CDC42 | x-ray diffraction | A | MN, UDP, SO4, MG | — |
| 7SO5 | Novel structural insights for a pair of monoclonal antibodies recognizing non-overlapping epitopes… | x-ray diffraction | A | — | — |
| 7SO7 | Novel structural insights for a pair of monoclonal antibodies recognizing non-overlapping epitopes… | x-ray diffraction | A, B | — | — |
| 7SO7 | Novel structural insights for a pair of monoclonal antibodies recognizing non-overlapping epitopes… | x-ray diffraction | A, B | — | — |
| P18177 | AlphaFold monomer V2.0 prediction for toxin B (P18177) | — | — | — |
Ligands
- MN · Manganese (II) ion · in 8 records
- SO4 · Sulfate ion · in 4 records
- UDP · Uridine-5'-diphosphate · in 4 records
- AGI · 5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one · in 2 records
- MG · Magnesium ion · in 2 records
- U2F · Uridine-5'-diphosphate-2-deoxy-2-fluoro-alpha-D-glucose · in 2 records
- IFM · 5-hydroxymethyl-3,4-dihydroxypiperidine · in 1 record
- NOY · (2R,3S,4R,5R)-5-(hydroxymethyl)piperidine-2,3,4-triol · in 1 record
- ZN · Zinc ion · in 1 record
Elsewhere
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