UniProt P13127
F-actin-capping protein subunit alpha-1 (P13127)
F-actin-capping protein subunit alpha-1 (UniProt P13127): 35 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 18 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P13127
- Protein
- F-actin-capping protein subunit alpha-1
- Experimental structures
- 35
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 18 · 4 records with a druggable one
Structures
36 records of P13127 in the MolNFT archive: 35 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1IZN | Crystal Structure of Actin Filament Capping Protein CapZ | x-ray diffraction | A, C | — | — |
| 1IZN | Crystal structure of actin filament capping protein capz | x-ray diffraction | A, C | — | — |
| 2KXP | Solution NMR structure of V-1 bound to capping protein (CP) | solution nmr | A | — | — |
| 2KXP | Solution NMR structure of V-1 bound to capping protein (cp) | solution nmr | A | — | — |
| 2KZ7 | Solution structure of the CARMIL CAH3a/b domain bound to capping protein (CP) | solution nmr | A | — | — |
| 2KZ7 | Solution structure of the carmil CAH3A/B domain bound to capping protein (cp) | solution nmr | A | — | — |
| 3AA0 | Crystal structure of Actin Capping Protein in complex with the Cp-binding motif derived from CARMIL | x-ray diffraction | A | — | — |
| 3AA0 | Crystal structure of actin capping protein in complex with the cp- binding motif derived from carmil | x-ray diffraction | A | — | — |
| 3AA1 | Crystal structure of Actin capping protein in complex with the Cp-binding motif derived from CKIP-1 | x-ray diffraction | A | — | — |
| 3AA1 | Crystal structure of actin capping protein in complex with the cp- binding motif derived from ckip-1 | x-ray diffraction | A | — | — |
| 3AA6 | Crystal structure of Actin capping protein in complex with the Cp-binding motif derived from CD2AP | x-ray diffraction | A | — | — |
| 3AA6 | Crystal structure of actin capping protein in complex with the cp- binding motif derived from CD2AP | x-ray diffraction | A | — | — |
| 3AA7 | Crystal structure of Actin capping protein | x-ray diffraction | A | — | — |
| 3AA7 | Crystal structure of actin capping protein | x-ray diffraction | A | — | — |
| 3AAA | Crystal Structure of Actin capping protein in complex with V-1 | x-ray diffraction | A | — | — |
| 3AAA | Crystal structure of actin capping protein in complex with V-1 | x-ray diffraction | A | — | — |
| 3AAE | Crystal structure of Actin capping protein in complex with CARMIL fragment | x-ray diffraction | A, C, E, G, I | — | — |
| 3AAE | Crystal structure of actin capping protein in complex with carmil fragment | x-ray diffraction | A, C, E, G, I | — | — |
| 3LK2 | Crystal structure of CapZ bound to the uncapping motif from CARMIL | x-ray diffraction | A | — | — |
| 3LK2 | Crystal structure of capz bound to the uncapping motif from carmil | x-ray diffraction | A | — | — |
| 3LK3 | Crystal structure of CapZ bound to the CPI and CSI uncapping motifs from CARMIL | x-ray diffraction | A | — | — |
| 3LK3 | Crystal structure of capz bound to the cpi and csi uncapping motifs from carmil | x-ray diffraction | A | — | — |
| 3LK4 | Crystal structure of CapZ bound to the uncapping motif from CD2AP | x-ray diffraction | A, D, G, J, M, P, S, V, Y, 1, 4, 7 | — | — |
| 3LK4 | Crystal structure of capz bound to the uncapping motif from CD2AP | x-ray diffraction | A, D, G, J, M, P, S, V, Y, 1, 4, 7 | — | — |
| 7DS2 | Crystal structure of actin capping protein in complex with twinflin-1 C-terminus tail | x-ray diffraction | A | — | — |
| 7DS3 | Crystal structure of actin capping protein in complex with twinflin-2 C-terminus tail | x-ray diffraction | A | — | — |
| 7DS4 | Crystal structure of actin capping protein in complex with twinflin-1 C-terminus tail F323K mutant | x-ray diffraction | A | — | 4 (best 0.62) |
| 7DS4 | Crystal structure of actin capping protein in complex with twinflin-1 C-terminus tail F323K mutant | x-ray diffraction | A | — | — |
| 7DS6 | Crystal structure of actin capping protein in complex with twinflin-1/CD2AP CPI chimera peptide… | x-ray diffraction | A | — | 4 (best 0.58) |
| 7DS6 | Crystal structure of actin capping protein in complex with twinflin- 1/CD2AP cpi chimera peptide… | x-ray diffraction | A | — | — |
| 7DS8 | Crystal structure of actin capping protein in complex with twinflin-1/CD2AP CPI chimera peptide… | x-ray diffraction | A | — | 4 (best 0.78) |
| 7DS8 | Crystal structure of actin capping protein in complex with twinflin- 1/CD2AP cpi chimera peptide… | x-ray diffraction | A | — | — |
| 7DSA | Crystal structure of actin capping protein in complex with V-1 (space group P62) | x-ray diffraction | A | MG | 6 (best 0.60) |
| 7DSA | Crystal structure of actin capping protein in complex with V-1 (space group P62) | x-ray diffraction | A | — | — |
| 7DSB | Crystal structure of actin capping protein in complex with V-1 and twinfilin C-terminal tail | x-ray diffraction | A | — | — |
| P13127 | AlphaFold monomer V2.0 prediction for F-actin-capping protein subunit alpha-1 (P13127) | predicted | A | — | — |
Ligands
- MG · Magnesium ion · in 1 record
Experiment against prediction
- 3LK2 chain A against the predicted model P13127: TM-score 0.95, RMSD 1.90 Å
- 3LK2 chain A against the predicted model P13127: TM-score 0.95, RMSD 1.90 Å
- 3AA6 chain A against the predicted model P13127: TM-score 0.95, RMSD 1.83 Å
- 3AA6 chain A against the predicted model P13127: TM-score 0.95, RMSD 1.83 Å
- 3LK3 chain A against the predicted model P13127: TM-score 0.95, RMSD 1.84 Å
- 3LK3 chain A against the predicted model P13127: TM-score 0.95, RMSD 1.84 Å
- 3LK4 chain P against the predicted model P13127: TM-score 0.95, RMSD 2.07 Å
- 3LK4 chain P against the predicted model P13127: TM-score 0.95, RMSD 2.07 Å
- 3LK4 chain V against the predicted model P13127: TM-score 0.95, RMSD 2.07 Å
- 3LK4 chain V against the predicted model P13127: TM-score 0.95, RMSD 2.07 Å
Elsewhere
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