UniProt P12676
Cholesterol oxidase (P12676)
Cholesterol oxidase (UniProt P12676), EC 1.1.3.6, 5.3.3.1: 46 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 7 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- P12676
- Protein
- Cholesterol oxidase
- EC
- 1.1.3.6, 5.3.3.1
- Experimental structures
- 46
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 7 · 2 records with a druggable one
Structures
47 records of P12676 in the MolNFT archive: 46 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1B4V | Cholesterol oxidase from streptomyces | x-ray diffraction | A | — | — |
| 1B4V | Cholesterol oxidase from streptomyces | x-ray diffraction | A | — | — |
| 1B8S | Cholesterol oxidase from streptomyces GLU361GLN mutant | x-ray diffraction | A | — | — |
| 1B8S | Cholesterol oxidase from streptomyces GLU361GLN mutant | x-ray diffraction | A | — | — |
| 1CBO | Cholesterol oxidase from streptomyces HIS447ASN mutant | x-ray diffraction | A | — | — |
| 1CBO | Cholesterol oxidase from streptomyces HIS447ASN mutant | x-ray diffraction | A | — | — |
| 1CC2 | Cholesterol oxidase from streptomyces HIS447GLN mutant | x-ray diffraction | A | — | — |
| 1CC2 | Cholesterol oxidase from streptomyces HIS447GLN mutant | x-ray diffraction | A | — | — |
| 1IJH | Cholesterol oxidase from streptomyces ASN485LEU mutant | x-ray diffraction | A | — | — |
| 1IJH | Cholesterol oxidase from streptomyces ASN485LEU mutant | x-ray diffraction | A | — | — |
| 1MXT | Atomic resolution structure of Cholesterol oxidase (Streptomyces sp. SA-COO) | x-ray diffraction | A | — | — |
| 1MXT | Atomic resolution structure of cholesterol oxidase (streptomyces sp. sa-coo) | x-ray diffraction | A | — | — |
| 1N1P | ATOMIC RESOLUTION STRUCTURE OF CHOLESTEROL OXIDASE @ pH 7.4 (STREPTOMYCES SP. SA-COO) | x-ray diffraction | A | — | — |
| 1N1P | Atomic resolution structure of cholesterol oxidase @ pH 7.4 (streptomyces sp. sa-coo) | x-ray diffraction | A | — | — |
| 1N4U | CHOLESTEROL OXIDASE FROM STREPTOMYCES @ pH 4.5 (STREPTOMYCES SP. SA-COO) | x-ray diffraction | A | — | — |
| 1N4U | Cholesterol oxidase from streptomyces @ pH 4.5 (streptomyces sp. sa- coo) | x-ray diffraction | A | — | — |
| 1N4V | ATOMIC RESOLUTION STRUCTURE OF CHOLESTEROL OXIDASE @pH 5.8 (STREPTOMYCES SP. SA-COO) | x-ray diffraction | A | — | — |
| 1N4V | Atomic resolution structure of cholesterol oxidase @pH 5.8 (streptomyces sp. sa-coo) | x-ray diffraction | A | — | — |
| 1N4W | ATOMIC RESOLUTION STRUCTURE OF CHOLESTEROL OXIDASE @ pH 7.3 (STREPTOMYCES SP. SA-COO) | x-ray diffraction | A | — | — |
| 1N4W | Atomic resolution structure of cholesterol oxidase @ pH 7.3 (streptomyces sp. sa-coo) | x-ray diffraction | A | — | — |
| 2GEW | Atomic resolution structure of cholesterol oxidase @ pH 9.0 (Streptomyces sp. SA-COO) | x-ray diffraction | A | — | — |
| 2GEW | Atomic resolution structure of cholesterol oxidase @ pH 9.0 (streptomyces sp. sa-coo) | x-ray diffraction | A | — | — |
| 3B3R | Crystal structure of Streptomyces cholesterol oxidase H447Q/E361Q mutant bound to glycerol (0.98A) | x-ray diffraction | A | — | — |
| 3B3R | Crystal structure of streptomyces cholesterol oxidase H447Q/E361Q mutant bound to glycerol (0.98A) | x-ray diffraction | A | — | — |
| 3B6D | Crystal Structure of Streptomyces Cholesterol Oxidase H447Q/E361Q mutant (1.2A) | x-ray diffraction | A | — | — |
| 3B6D | Crystal structure of streptomyces cholesterol oxidase H447Q/E361Q mutant (1.2A) | x-ray diffraction | A | — | — |
| 3CNJ | Cholesterol oxidase from Streptomyces sp. F359W mutant (0.95A) | x-ray diffraction | A | — | — |
| 3CNJ | Cholesterol oxidase from streptomyces sp. F359W mutant (0.95A) | x-ray diffraction | A | — | — |
| 3GYI | Cholesterol oxidase from Streptomyces sp. N485D mutant (1.0A) | x-ray diffraction | A | — | — |
| 3GYI | Cholesterol oxidase from streptomyces sp. N485D mutant (1.0A) | x-ray diffraction | A | — | — |
| 3GYJ | Cholesterol oxidase from Streptomyces sp. N485L mutant (0.92A) | x-ray diffraction | A | — | — |
| 3GYJ | Cholesterol oxidase from streptomyces sp. N485L mutant (0.92A) | x-ray diffraction | A | — | — |
| 4REK | Crystal structure and charge density studies of cholesterol oxidase from Brevibacterium sterolicum… | x-ray diffraction | A | — | — |
| 4REK | Crystal structure and charge density studies of cholesterol oxidase from brevibacterium sterolicum… | x-ray diffraction | A | — | — |
| 4U2L | Dithionite reduced cholesterol in complex with sulfite | x-ray diffraction | A | — | — |
| 4U2L | Dithionite reduced cholesterol in complex with sulfite | x-ray diffraction | A | — | — |
| 4U2S | Cholesterol oxidase in the reduced state complexed with isopropanol | x-ray diffraction | A | — | — |
| 4U2S | Cholesterol oxidase in the reduced state complexed with isopropanol | x-ray diffraction | A | — | — |
| 4U2T | Cholesterol oxidase in the oxidised state complexed with isopropanol | x-ray diffraction | A | — | — |
| 4U2T | Cholesterol oxidase in the oxidised state complexed with isopropanol | x-ray diffraction | A | — | — |
| 4XWR | X-ray structure of perdeuterated Cholesterol Oxidase from Streptomyces SA-COO | x-ray diffraction | A | FAD, SO4 | 3 (best 0.86) |
| 4XWR | X-ray structure of perdeuterated cholesterol oxidase from streptomyces sa-coo | x-ray diffraction | A | — | — |
| 4XXG | Structure of protonated Cholesterol Oxidase from Streptomyces SA-COO | x-ray diffraction | A | — | — |
| 4XXG | Structure of protonated cholesterol oxidase from streptomyces sa-coo | x-ray diffraction | A | — | — |
| 5KWF | Joint X-ray Neutron Structure of Cholesterol Oxidase | x-ray diffraction, neutron diffraction | A | FAD | 4 (best 0.86) |
| 5KWF | Joint X-ray neutron structure of cholesterol oxidase | x-ray diffraction; neutron diffraction | A | FAD | — |
| P12676 | AlphaFold monomer V2.0 prediction for cholesterol oxidase (P12676) | predicted | A | — | — |
Ligands
Experiment against prediction
- 4XWR chain A against the predicted model P12676: TM-score 1.00, RMSD 0.15 Å
- 4XWR chain A against the predicted model P12676: TM-score 1.00, RMSD 0.15 Å
- 3GYI chain A against the predicted model P12676: TM-score 1.00, RMSD 0.16 Å
- 3GYI chain A against the predicted model P12676: TM-score 1.00, RMSD 0.16 Å
- 4REK chain A against the predicted model P12676: TM-score 1.00, RMSD 0.16 Å
- 4REK chain A against the predicted model P12676: TM-score 1.00, RMSD 0.16 Å
- 3B6D chain A against the predicted model P12676: TM-score 1.00, RMSD 0.17 Å
- 3B6D chain A against the predicted model P12676: TM-score 1.00, RMSD 0.17 Å
- 3CNJ chain A against the predicted model P12676: TM-score 1.00, RMSD 0.17 Å
- 3CNJ chain A against the predicted model P12676: TM-score 1.00, RMSD 0.17 Å
Elsewhere
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