UniProt P0C0S1
Small-conductance mechanosensitive channel (P0C0S1)
Small-conductance mechanosensitive channel (UniProt P0C0S1): 12 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P0C0S1
- Protein
- Small-conductance mechanosensitive channel
- Experimental structures
- 12
- Predicted models
- 1
- Ligands
- 4
Structures
13 records of P0C0S1 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2OAU | Mechanosensitive Channel of Small Conductance (MscS) | x-ray diffraction | A, B, C, D, E, F, G | — | — |
| 2OAU | Mechanosensitive channel of small conductance (mscs) | x-ray diffraction | A, B, C, D, E, F, G | — | — |
| 3UDC | Crystal structure of a membrane protein | x-ray diffraction | A, B, C, D, E, F, G | — | — |
| 3UDC | Crystal structure of a membrane protein | x-ray diffraction | A, B, C, D, E, F, G | — | — |
| 4HWA | Crystal Structure of Escherichia coli MscS Wildtype (Open State) | x-ray diffraction | A, B, C, D, E, F, G | — | — |
| 4HWA | Crystal structure of escherichia COLI mscs wildtype (open state) | x-ray diffraction | A, B, C, D, E, F, G | — | — |
| 6PWN | Mscs nanodisc with N-terminal his-tag | electron microscopy | A, B, C, D, E, F, G | POV, R16 | — |
| 6PWO | MSCS DDM | electron microscopy | A, B, C, D, E, F, G | — | — |
| 6PWP | Mscs nanodisc | electron microscopy | A, B, C, D, E, F, G | — | — |
| 6RLD | Structure of the mechanosensitive channel mscs embedded in the membrane bilayer | electron microscopy | A, B, C, D, E, F, G | PCW | — |
| 7ONL | Mechanosensitive channel mscs solubilized with ddm in closed conformation | electron microscopy | A, B, C, D, E, F, G | — | — |
| 7RAZ | Small conductance mechanosensitive channel mscs | electron microscopy | A, B, C, D, E, F, G | PTY | — |
| P0C0S1 | AlphaFold monomer V2.0 prediction for small-conductance mechanosensitive channel (P0C0S1) | predicted | A | — | — |
Ligands
Experiment against prediction
- 3UDC chain A against the predicted model Q8R6L9: TM-score 0.98, RMSD 1.01 Å
- 3UDC chain A against the predicted model Q8R6L9: TM-score 0.98, RMSD 1.01 Å
- 7RAZ chain A against the predicted model P0C0S1: TM-score 0.93, RMSD 1.65 Å
- 4HWA chain A against the predicted model P0C0S1: TM-score 0.88, RMSD 2.76 Å
- 4HWA chain A against the predicted model P0C0S1: TM-score 0.88, RMSD 2.76 Å
- 2OAU chain A against the predicted model P0C0S1: TM-score 0.83, RMSD 3.21 Å
- 2OAU chain A against the predicted model P0C0S1: TM-score 0.83, RMSD 3.21 Å
- 7ONL chain A against the predicted model P0C0S1: TM-score 0.82, RMSD 3.39 Å
- 6RLD chain A against the predicted model P0C0S1: TM-score 0.81, RMSD 3.34 Å
- 6PWO chain A against the predicted model P0C0S1: TM-score 0.80, RMSD 3.20 Å
Elsewhere
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