UniProt P0A8M3
Threonine--tRNA ligase (P0A8M3)
Threonine--tRNA ligase (UniProt P0A8M3): 30 experimental structures and 1 predicted model on GenesisL1, 6 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P0A8M3
- Protein
- Threonine--tRNA ligase
- Experimental structures
- 30
- Predicted models
- 1
- Pockets
- 6 · 1 record with a druggable one
Structures
31 records of P0A8M3 in the MolNFT archive: 30 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1EVK | Crystal structure of a truncated form of threonyl-tRNA synthetase with the ligand threonine | x-ray diffraction | A, B | — | — |
| 1EVK | Crystal structure of a truncated form of threonyl-tRNA synthetase with the ligand threonine | x-ray diffraction | A, B | — | — |
| 1EVL | Crystal structure of a truncated form of threonyl-tRNA synthetase with a threonyl adenylate analog | x-ray diffraction | A, B, C, D | — | — |
| 1EVL | Crystal structure of a truncated form of threonyl-tRNA synthetase with a threonyl adenylate analog | x-ray diffraction | A, B, C, D | — | — |
| 1FYF | Crystal structure of a truncated form of threonyl-tRNA synthetase complexed with a seryl adenylate… | x-ray diffraction | A, B | — | — |
| 1FYF | Crystal structure of a truncated form of threonyl-tRNA synthetase complexed with a seryl adenylate… | x-ray diffraction | A, B | — | — |
| 1KOG | Crystal structure of E. coli threonyl-tRNA synthetase interacting with the essential domain of its… | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 1KOG | Crystal structure of E. COLI threonyl-tRNA synthetase interacting with the essential domain of its… | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 1QF6 | Structure of E. COLI threonyl-tRNA synthetase complexed with its cognate tRNA | x-ray diffraction | A | — | — |
| 1QF6 | Structure of E. COLI threonyl-tRNA synthetase complexed with its cognate tRNA | x-ray diffraction | A | — | — |
| 1TJE | Crystal structure of the editing domain of threonyl-tRNA synthetase | x-ray diffraction | A | — | — |
| 1TJE | Crystal structure of the editing domain of threonyl-tRNA synthetase | x-ray diffraction | A | — | — |
| 1TKE | Crystal structure of the editing domain of threonyl-tRNA synthetase complexed with serine | x-ray diffraction | A | — | — |
| 1TKE | Crystal structure of the editing domain of threonyl-tRNA synthetase complexed with serine | x-ray diffraction | A | — | — |
| 1TKG | Crystal structure of the editing domain of threonyl-tRNA synthetase complexed with an analog of… | x-ray diffraction | A | — | — |
| 1TKG | Crystal structure of the editing domain of threonyl-tRNA synthetase complexed with an analog of… | x-ray diffraction | A | — | — |
| 1TKY | Crystal structure of the editing domain of threonyl-tRNA synthetase complexed with… | x-ray diffraction | A | — | — |
| 1TKY | Crystal structure of the editing domain of threonyl-tRNA synthetase complexed with… | x-ray diffraction | A | — | — |
| 4HWO | Crystal structure of E. coli Threonyl-tRNA synthetase bound to a novel inhibitor | x-ray diffraction | A, B | — | — |
| 4HWO | Crystal structure of E. COLI threonyl-tRNA synthetase bound to a novel inhibitor | x-ray diffraction | A, B | — | — |
| 4HWP | Crystal structure of E. coli Threonyl-tRNA synthetase bound to a novel inhibitor | x-ray diffraction | A, B | — | — |
| 4HWP | Crystal structure of E. COLI threonyl-tRNA synthetase bound to a novel inhibitor | x-ray diffraction | A, B | — | — |
| 4HWR | Crystal structure of E. coli Threonyl-tRNA synthetase bound to a novel inhibitor | x-ray diffraction | A, B | — | — |
| 4HWR | Crystal structure of E. COLI threonyl-tRNA synthetase bound to a novel inhibitor | x-ray diffraction | A, B | — | — |
| 4HWS | Crystal structure of E. coli Threonyl-tRNA synthetase bound to a novel inhibitor | x-ray diffraction | A, B | — | — |
| 4HWS | Crystal structure of E. COLI threonyl-tRNA synthetase bound to a novel inhibitor | x-ray diffraction | A, B | — | — |
| 4P3O | Structural Basis for Full-Spectrum Inhibition of Threonyl-tRNA Synthetase by Borrelidin 2 | x-ray diffraction | A, B | — | — |
| 4P3O | Structural basis for full-spectrum inhibition of threonyl-tRNA synthetase by borrelidin 2 | x-ray diffraction | A, B | — | — |
| 4P3P | Structural Basis for Full-Spectrum Inhibition of Threonyl-tRNA Synthetase by Borrelidin 3 | x-ray diffraction | A, B | — | — |
| 4P3P | Structural basis for full-spectrum inhibition of threonyl-tRNA synthetase by borrelidin 3 | x-ray diffraction | A, B | — | — |
| P0A8M3 | AlphaFold monomer V2.0 prediction for threonine--tRNA ligase (P0A8M3) | predicted | A | — | 6 (best 0.69) |
Experiment against prediction
- 1TKG chain A against the predicted model P0A8M3: TM-score 0.99, RMSD 0.49 Å
- 1TKG chain A against the predicted model P0A8M3: TM-score 0.99, RMSD 0.49 Å
- 1EVK chain B against the predicted model P0A8M3: TM-score 0.99, RMSD 0.55 Å
- 1EVK chain B against the predicted model P0A8M3: TM-score 0.99, RMSD 0.55 Å
- 4HWR chain A against the predicted model P0A8M3: TM-score 0.99, RMSD 0.64 Å
- 4HWR chain A against the predicted model P0A8M3: TM-score 0.99, RMSD 0.64 Å
- 1TJE chain A against the predicted model P0A8M3: TM-score 0.99, RMSD 0.58 Å
- 1TJE chain A against the predicted model P0A8M3: TM-score 0.99, RMSD 0.58 Å
- 1FYF chain A against the predicted model P0A8M3: TM-score 0.99, RMSD 0.84 Å
- 1FYF chain A against the predicted model P0A8M3: TM-score 0.99, RMSD 0.84 Å
Elsewhere
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