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Ligand · TSB

TSB · 5'-O-(N-(L-threonyl)-sulfamoyl)adenosine

TSB, 5'-O-(N-(L-threonyl)-sulfamoyl)adenosine (C14 H21 N7 O8 S, 447.4 g/mol), in the MolNFT structures on GenesisL1: bound in 14 records (7 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the…

Component
TSB
Formula
C14 H21 N7 O8 S
Class
ligand
Structures
14
PDB entries
7

Binding sites

TSB in 14 structures; the first of them:

  • 1EVL · Crystal structure of a truncated form of threonyl-tRNA synthetase with a threonyl… · TSB A2002 · binds MET332, CYS334, ARG363, GLU365, MET374, ARG375, VAL376, PHE379 and 16 more
  • 1KOG · Crystal structure of E. coli threonyl-tRNA synthetase interacting with the essential… · TSB A2002 · binds MET332, CYS334, ARG363, GLU365, MET374, ARG375, VAL376, PHE379 and 18 more
  • 1NYQ · Structure of Staphylococcus aureus threonyl-tRNA synthetase complexed with an analogue of… · TSB A1002 · binds TYR313, MET334, CYS336, MET363, ARG365, GLU367, GLN376, ARG377 and 18 more
  • 1WK9 · Structural basis for non-cognate amino acid discrimination by the valyl-tRNA synthetase… · TSB A999 · binds THR214, VAL215, ARG216, THR219, ASP223, ALA259, VAL260, GLU261 and 9 more
  • 3PD5 · Crystal structure of the editing domain of threonyl-tRNA synthetase from Pyrococcus… · TSB A501 · binds ALA19, LEU20, ILE43, SER44, VAL45, PRO80, PHE81, ALA82 and 10 more
  • 3UH0 · Crystal structure of the yeast mitochondrial threonyl-tRNA synthetase (MST1) in complex… · TSB A1002 · binds MET131, CYS133, ARG162, GLU164, LEU172, THR173, ARG174, LEU175 and 17 more
  • 4YYE · Crystal structure of the yeast mitochondrial threonyl-tRNA synthetase (MST1) in complex… · TSB A502 · binds MET131, CYS133, ARG162, GLU164, LEU172, THR173, ARG174, LEU175 and 17 more
  • 1EVL · Crystal structure of a truncated form of threonyl-tRNA synthetase with a threonyl… · TSB A2002 · binds MET332, CYS334, ARG363, GLU365, MET374, ARG375, VAL376, PHE379 and 16 more
  • 1KOG · Crystal structure of E. COLI threonyl-tRNA synthetase interacting with the essential… · TSB A2002 · binds MET332, CYS334, ARG363, GLU365, MET374, ARG375, VAL376, PHE379 and 18 more
  • 1NYQ · Structure of staphylococcus aureus threonyl-tRNA synthetase complexed with an analogue of… · TSB A1002 · binds TYR313, MET334, CYS336, MET363, ARG365, GLU367, GLN376, ARG377 and 18 more
  • 1WK9 · Structural basis for non-cognate amino acid discrimination by the valyl-tRNA synthetase… · TSB A999 · binds THR214, VAL215, ARG216, THR219, ASP223, ALA259, VAL260, GLU261 and 9 more
  • 3PD5 · Crystal structure of the editing domain of threonyl-tRNA synthetase from pyrococcus… · TSB A501 · binds ALA19, LEU20, ILE43, SER44, VAL45, PRO80, PHE81, ALA82 and 10 more
  • 3UH0 · Crystal structure of the yeast mitochondrial threonyl-tRNA synthetase (MST1) in complex… · TSB A1002 · binds MET131, CYS133, ARG162, GLU164, LEU172, THR173, ARG174, LEU175 and 17 more
  • 4YYE · Crystal structure of the yeast mitochondrial threonyl-tRNA synthetase (MST1) in complex… · TSB A502 · binds MET131, CYS133, ARG162, GLU164, LEU172, THR173, ARG174, LEU175 and 17 more

Residues it binds most

ARG 36, GLN 34, ALA 36, HIS 34, MET 34, GLY 40, CYS 34, LEU 30, THR 36, TYR 38 (residue and the binding sites it lines).

Found with

  • ZN · Zinc ion
  • SO4 · Sulfate ion
  • GOL · Glycerol

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