UniProt P08799
Myosin-2 heavy chain (P08799)
Myosin-2 heavy chain (UniProt P08799): 95 experimental structures and 1 predicted model on GenesisL1, 7 ligands bound, 30 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P08799
- Protein
- Myosin-2 heavy chain
- Experimental structures
- 95
- Predicted models
- 1
- Ligands
- 7
- Pockets
- 30 · 3 records with a druggable one
Structures
96 records of P08799 in the MolNFT archive: 95 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1D0X | Dictyostelium myosin S1DC (motor domain fragment) complexed with M-nitrophenyl… | x-ray diffraction | A | — | — |
| 1D0X | Dictyostelium myosin S1DC (motor domain fragment) complexed with M- nitrophenyl… | x-ray diffraction | A | — | — |
| 1D0Y | Dictyostelium myosin S1DC (motor domain fragment) complexed with O-nitrophenyl… | x-ray diffraction | A | — | — |
| 1D0Y | Dictyostelium myosin S1DC (motor domain fragment) complexed with O- nitrophenyl… | x-ray diffraction | A | — | — |
| 1D0Z | Dictyostelium myosin S1DC (motor domain fragment) complexed with P-nitrophenyl… | x-ray diffraction | A | — | — |
| 1D0Z | Dictyostelium myosin S1DC (motor domain fragment) complexed with P- nitrophenyl… | x-ray diffraction | A | — | — |
| 1D1A | Dictyostelium myosin S1DC (motor domain fragment) complexed with O,P-dinitrophenyl… | x-ray diffraction | A | — | — |
| 1D1A | Dictyostelium myosin S1DC (motor domain fragment) complexed with O,P- dinitrophenyl… | x-ray diffraction | A | — | — |
| 1D1B | Dictyostelium myosin S1DC (motor domain fragment) complexed with O,P-dinitrophenyl… | x-ray diffraction | A | — | — |
| 1D1B | Dictyostelium myosin S1DC (motor domain fragment) complexed with O,P- dinitrophenyl… | x-ray diffraction | A | — | — |
| 1D1C | Dictyostelium myosin S1DC (motor domain fragment) complexed with N-methyl-O-nitrophenyl… | x-ray diffraction | A | — | — |
| 1D1C | Dictyostelium myosin S1DC (motor domain fragment) complexed with N- methyl-O-nitrophenyl… | x-ray diffraction | A | — | — |
| 1FMV | Crystal structure of the apo motor domain of dictyostellium myosin II | x-ray diffraction | A | — | — |
| 1FMV | Crystal structure of the apo motor domain of dictyostellium myosin II | x-ray diffraction | A | — | — |
| 1FMW | Crystal structure of the mgatp complex for the motor domain of dictyostelium myosin II | x-ray diffraction | A | — | — |
| 1FMW | Crystal structure of the mgatp complex for the motor domain of dictyostelium myosin II | x-ray diffraction | A | — | — |
| 1G8X | Structure of a genetically engineered molecular motor | x-ray diffraction | A, B | — | — |
| 1G8X | Structure of a genetically engineered molecular motor | x-ray diffraction | A, B | — | — |
| 1JWY | Crystal structure of the dynamin a GTPase domain complexed with GDP, determined as myosin fusion | x-ray diffraction | A | — | — |
| 1JWY | Crystal structure of the dynamin a GTPase domain complexed with GDP, determined as myosin fusion | x-ray diffraction | A | — | — |
| 1JX2 | Crystal structure of the nucleotide-free dynamin a GTPase domain, determined as myosin fusion | x-ray diffraction | A | — | — |
| 1JX2 | Crystal structure of the nucleotide-free dynamin a GTPase domain, determined as myosin fusion | x-ray diffraction | A | — | — |
| 1LVK | X-ray crystal structure of the mg (dot) 2'(3')-O-(N-methylanthraniloyl) nucleotide bound to… | x-ray diffraction | A | — | — |
| 1LVK | X-ray crystal structure of the mg (dot) 2'(3')-O-(N- methylanthraniloyl) nucleotide bound to… | x-ray diffraction | A | — | — |
| 1MMA | X-ray structures of the mgadp, mgatpgammas, and mgamppnp complexes of the dictyostelium discoideum… | x-ray diffraction | A | — | — |
| 1MMA | X-ray structures of the mgadp, mgatpgammas, and mgamppnp complexes of the dictyostelium discoideum… | x-ray diffraction | A | — | — |
| 1MMD | Truncated head of myosin from dictyostelium discoideum complexed with mgadp-BEF3 | x-ray diffraction | A | — | — |
| 1MMD | Truncated head of myosin from dictyostelium discoideum complexed with mgadp-BEF3 | x-ray diffraction | A | — | — |
| 1MMG | X-ray structures of the mgadp, mgatpgammas, and mgamppnp complexes of the dictyostelium discoideum… | x-ray diffraction | A | — | — |
| 1MMG | X-ray structures of the mgadp, mgatpgammas, and mgamppnp complexes of the dictyostelium discoideum… | x-ray diffraction | A | — | — |
| 1MMN | X-ray structures of the mgadp, mgatpgammas, and mgamppnp complexes of the dictyostelium discoideum… | x-ray diffraction | A | — | — |
| 1MMN | X-ray structures of the mgadp, mgatpgammas, and mgamppnp complexes of the dictyostelium discoideum… | x-ray diffraction | A | — | — |
| 1MND | Truncated head of myosin from dictyostelium discoideum complexed with mgadp-ALF4 | x-ray diffraction | A | — | — |
| 1MND | Truncated head of myosin from dictyostelium discoideum complexed with mgadp-ALF4 | x-ray diffraction | A | — | — |
| 1MNE | Truncated head of myosin from dictyostelium discoideum complexed with mg-pyrophosphate | x-ray diffraction | A | — | — |
| 1MNE | Truncated head of myosin from dictyostelium discoideum complexed with mg-pyrophosphate | x-ray diffraction | A | — | — |
| 1VOM | Complex between dictyostelium myosin and mgadp and vanadate at 1.9A resolution | x-ray diffraction | A | — | — |
| 1VOM | Complex between dictyostelium myosin and mgadp and vanadate at 1.9A resolution | x-ray diffraction | A | — | — |
| 1W9I | Myosin II Dictyostelium discoideum motor domain S456Y bound with MgADP-BeFx | x-ray diffraction | A | — | — |
| 1W9I | Myosin II dictyostelium discoideum motor domain S456Y bound with mgadp-befx | x-ray diffraction | A | — | — |
| 1W9J | Myosin II Dictyostelium discoideum motor domain S456Y bound with MgADP-AlF4 | x-ray diffraction | A | — | — |
| 1W9J | Myosin II dictyostelium discoideum motor domain S456Y bound with mgadp-ALF4 | x-ray diffraction | A | — | — |
| 1W9K | Dictyostelium discoideum Myosin II motor domain S456E with bound MgADP-BeFx | x-ray diffraction | A | — | — |
| 1W9K | Dictyostelium discoideum myosin II motor domain S456E with bound mgadp-befx | x-ray diffraction | A | — | — |
| 1W9L | Myosin II Dictyostelium discoideum motor domain S456E bound with MgADP-AlF4 | x-ray diffraction | A | — | — |
| 1W9L | Myosin II dictyostelium discoideum motor domain S456E bound with mgadp-ALF4 | x-ray diffraction | A | — | — |
| 1YV3 | The structural basis of blebbistatin inhibition and specificity for myosin II | x-ray diffraction | A | — | — |
| 1YV3 | The structural basis of blebbistatin inhibition and specificity for myosin II | x-ray diffraction | A | — | — |
| 2AKA | Structure of the nucleotide-free myosin II motor domain from Dictyostelium discoideum fused to the… | x-ray diffraction | A | — | — |
| 2AKA | Structure of the nucleotide-free myosin II motor domain from dictyostelium discoideum fused to the… | x-ray diffraction | A | — | — |
| 2JHR | Crystal structure of myosin-2 motor domain in complex with ADP- metavanadate and pentabromopseudilin | x-ray diffraction | A | — | — |
| 2JHR | Crystal structure of myosin-2 motor domain in complex with ADP- metavanadate and pentabromopseudilin | x-ray diffraction | A | — | — |
| 2JJ9 | Crystal structure of myosin-2 in complex with ADP-metavanadate | x-ray diffraction | A | — | — |
| 2JJ9 | Crystal structure of myosin-2 in complex with ADP-metavanadate | x-ray diffraction | A | — | — |
| 2X9H | Crystal structure of myosin-2 motor domain in complex with ADP- metavanadate and… | x-ray diffraction | A | — | — |
| 2X9H | Crystal structure of myosin-2 motor domain in complex with ADP-metavanadate and pentachlorocarbazole | x-ray diffraction | A | — | — |
| 2XEL | Molecular Mechanism of Pentachloropseudilin Mediated Inhibition of Myosin Motor Activity | x-ray diffraction | A | — | — |
| 2XEL | Molecular mechanism of pentachloropseudilin mediated inhibition of myosin motor activity | x-ray diffraction | A | — | — |
| 2XO8 | Crystal Structure of Myosin-2 in Complex with Tribromodichloropseudilin | x-ray diffraction | A | — | — |
| 2XO8 | Crystal structure of myosin-2 in complex with tribromodichloropseudilin | x-ray diffraction | A | — | — |
36 records more on the page itself.
Ligands
- MG · Magnesium ion · in 5 records
- AD9 · Adp metavanadate · in 4 records
- ADP · Adenosine-5'-diphosphate · in 2 records
- BIT · (-)-1-phenyl-1,2,3,4-tetrahydro-4-hydroxypyrrolo[2,3-B]-7-methylquinolin-4-one · in 2 records
- Q5Q · 3,6-dibromo-1-(hydroxymethyl)carbazole · in 2 records
- FRU · beta-D-fructofuranose · in 1 record
- GLC · alpha-D-glucopyranose · in 1 record
Experiment against prediction
- 1MND chain A against the predicted model P08799: TM-score 0.98, RMSD 1.45 Å
- 1MND chain A against the predicted model P08799: TM-score 0.98, RMSD 1.45 Å
- 4AE3 chain A against the predicted model P08799: TM-score 0.98, RMSD 1.59 Å
- 4AE3 chain A against the predicted model P08799: TM-score 0.98, RMSD 1.59 Å
- 1YV3 chain A against the predicted model P08799: TM-score 0.98, RMSD 1.55 Å
- 1YV3 chain A against the predicted model P08799: TM-score 0.98, RMSD 1.55 Å
- 3BZ7 chain A against the predicted model P08799: TM-score 0.98, RMSD 1.57 Å
- 3BZ7 chain A against the predicted model P08799: TM-score 0.98, RMSD 1.57 Å
- 3BZ8 chain A against the predicted model P08799: TM-score 0.97, RMSD 1.62 Å
- 3BZ8 chain A against the predicted model P08799: TM-score 0.97, RMSD 1.62 Å
Elsewhere
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