UniProt P08758
Annexin A5 (P08758)
Annexin A5 (UniProt P08758): 30 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 16 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P08758
- Protein
- Annexin A5
- Experimental structures
- 30
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 16 · 4 records with a druggable one
Structures
31 records of P08758 in the MolNFT archive: 30 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1ANW | The effect of metal binding on the structure of annexin V and implications for membrane binding | x-ray diffraction | A, B | — | — |
| 1ANW | The effect of metal binding on the structure of annexin V and implications for membrane binding | x-ray diffraction | A, B | — | — |
| 1ANX | The crystal structure of a new high-calcium form of annexin V | x-ray diffraction | A, B, C | — | — |
| 1ANX | The crystal structure of a new high-calcium form of annexin V | x-ray diffraction | A, B, C | — | — |
| 1AVH | Crystal and molecular structure of human annexin V after refinement. implications for structure… | x-ray diffraction | A, B | — | — |
| 1AVH | Crystal and molecular structure of human annexin V after refinement. implications for structure… | x-ray diffraction | A, B | — | — |
| 1AVR | Crystal and molecular structure of human annexin V after refinement. implications for structure… | x-ray diffraction | A | — | — |
| 1AVR | Crystal and molecular structure of human annexin V after refinement. implications for structure… | x-ray diffraction | A | — | — |
| 1HAK | Crystal structure of recombinant human placental annexin V complexed with K-201 as a calcium… | x-ray diffraction | B, A | — | — |
| 1HAK | Crystal structure of recombinant human placental annexin V complexed with K-201 as a calcium… | x-ray diffraction | B, A | — | — |
| 1HVD | Structural and electrophysiological analysis of annexin V mutants. mutagenesis of human annexin V… | x-ray diffraction | A | — | — |
| 1HVD | Structural and electrophysiological analysis of annexin V mutants. mutagenesis of human annexin V… | x-ray diffraction | A | — | — |
| 1HVE | Structural and electrophysiological analysis of annexin V mutants. mutagenesis of human annexin V… | x-ray diffraction | A | — | — |
| 1HVE | Structural and electrophysiological analysis of annexin V mutants. mutagenesis of human annexin V… | x-ray diffraction | A | — | — |
| 1HVF | Structural and electrophysiological analysis of annexin V mutants. mutagenesis of human annexin V… | x-ray diffraction | A | — | — |
| 1HVF | Structural and electrophysiological analysis of annexin V mutants. mutagenesis of human annexin V… | x-ray diffraction | A | — | — |
| 1HVG | Structural and electrophysiological analysis of annexin V mutants. mutagenesis of human annexin V… | x-ray diffraction | A | — | — |
| 1HVG | Structural and electrophysiological analysis of annexin V mutants. mutagenesis of human annexin V… | x-ray diffraction | A | — | — |
| 1SAV | Human annexin V with proline substitution by thioproline | x-ray diffraction | A | — | — |
| 1SAV | Human annexin V with proline substitution by thioproline | x-ray diffraction | A | — | — |
| 2XO2 | Human Annexin V with incorporated Methionine analogue Azidohomoalanine | x-ray diffraction | A | — | — |
| 2XO2 | Human annexin V with incorporated methionine analogue azidohomoalanine | x-ray diffraction | A | — | — |
| 2XO3 | Human Annexin V with incorporated Methionine analogue Homopropargylglycine | x-ray diffraction | A | — | — |
| 2XO3 | Human annexin V with incorporated methionine analogue homopropargylglycine | x-ray diffraction | A | — | — |
| 6K22 | Crystal structure of Ca-bound human Annexin A5 in low salt condition | x-ray diffraction | A | CA | 4 (best 0.52) |
| 6K22 | Crystal structure of ca-bound human annexin A5 in low salt condition | x-ray diffraction | A | CA | — |
| 6K25 | Crystal structure of Ca-unbound human Annexin A5 in low salt condition | x-ray diffraction | A | — | 4 (best 0.55) |
| 6K25 | Crystal structure of ca-unbound human annexin A5 in low salt condition | x-ray diffraction | A | — | — |
| 8H0J | Annexin A5 mutant | x-ray diffraction | A | CA | 4 (best 0.54) |
| 8H9Z | Annexin A5 protein mutant | x-ray diffraction | A | CA | 4 (best 0.53) |
| P08758 | AlphaFold monomer V2.0 prediction for annexin A5 (P08758) | predicted | A | — | — |
Ligands
- CA · Calcium ion · in 4 records
Experiment against prediction
- 1HVG chain A against the predicted model P08758: TM-score 0.99, RMSD 0.80 Å
- 1HVG chain A against the predicted model P08758: TM-score 0.99, RMSD 0.80 Å
- 1ANX chain C against the predicted model P08758: TM-score 0.98, RMSD 0.97 Å
- 6K22 chain A against the predicted model P08758: TM-score 0.98, RMSD 0.83 Å
- 6K22 chain A against the predicted model P08758: TM-score 0.98, RMSD 0.83 Å
- 1ANX chain A against the predicted model P08758: TM-score 0.98, RMSD 0.97 Å
- 1ANX chain A against the predicted model P08758: TM-score 0.98, RMSD 0.97 Å
- 2XO3 chain A against the predicted model P08758: TM-score 0.98, RMSD 0.88 Å
- 2XO3 chain A against the predicted model P08758: TM-score 0.98, RMSD 0.88 Å
- 1ANX chain B against the predicted model P08758: TM-score 0.98, RMSD 0.98 Å
Elsewhere
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