UniProt P05161
Ubiquitin-like protein ISG15 (P05161)
Ubiquitin-like protein ISG15 (UniProt P05161): 29 experimental structures on GenesisL1, 2 ligands bound, 36 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P05161
- Protein
- Ubiquitin-like protein ISG15
- Experimental structures
- 29
- Predicted models
- 0
- Ligands
- 2
- Pockets
- 36 · 4 records with a druggable one
Structures
29 records of P05161 in the MolNFT archive: 29 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1Z2M | Crystal Structure of ISG15, the Interferon-Induced Ubiquitin Cross Reactive Protein | x-ray diffraction | A | — | — |
| 1Z2M | Crystal structure of ISG15, the interferon-induced ubiquitin cross reactive protein | x-ray diffraction | A | — | — |
| 2HJ8 | Solution NMR structure of the C-terminal domain of the interferon alpha-inducible ISG15 protein… | solution nmr | A | — | — |
| 2HJ8 | Solution NMR structure of the C-terminal domain of the interferon alpha-inducible ISG15 protein… | solution nmr | A | — | — |
| 3PHX | OTU Domain of Crimean Congo Hemorrhagic Fever Virus in complex with ISG15 | x-ray diffraction | B | — | — |
| 3PHX | Otu domain of crimean congo hemorrhagic fever virus in complex with ISG15 | x-ray diffraction | B | — | — |
| 3PSE | Structure of a viral OTU domain protease bound to interferon-stimulated gene 15 (ISG15) | x-ray diffraction | B | — | — |
| 3PSE | Structure of a viral otu domain protease bound to interferon- stimulated gene 15 (ISG15) | x-ray diffraction | B | — | — |
| 3R66 | Crystal structure of human ISG15 in complex with NS1 N-terminal region from influenza virus B… | x-ray diffraction | C, D | — | — |
| 3R66 | Crystal structure of human ISG15 in complex with NS1 N-terminal region from influenza virus B… | x-ray diffraction | C, D | — | — |
| 3RT3 | Complex of influenza virus protein with host anti-viral factor | x-ray diffraction | B | — | — |
| 3RT3 | Complex of influenza virus protein with host anti-viral factor | x-ray diffraction | B | — | — |
| 3SDL | Crystal structure of human ISG15 in complex with NS1 N-terminal region from influenza B virus… | x-ray diffraction | C, D | — | — |
| 3SDL | Crystal structure of human ISG15 in complex with NS1 N-terminal region from influenza B virus… | x-ray diffraction | C, D | — | — |
| 5TL6 | Crystal structure of SARS-cov papain-like protease in complex with the C-terminal domain of human… | x-ray diffraction | C, A | AYE | — |
| 5W8T | Crystal structure of MERS-cov papain-like protease in complex with the C-terminal domain of human… | x-ray diffraction | B, D | AYE | — |
| 5W8U | Crystal structure of MERS-CoV papain-like protease in complex with the C-terminal domain of human… | x-ray diffraction | B, D | AYE | — |
| 5W8U | Crystal structure of MERS-cov papain-like protease in complex with the C-terminal domain of human… | x-ray diffraction | B, D | AYE | — |
| 6BI8 | X-ray structure of MERS coronavirus papain-like protease in complex with human ISG15 | x-ray diffraction | C, D | AYE | — |
| 6BI8 | X-ray structure of MERS coronavirus papain-like protease in complex with human ISG15 | x-ray diffraction | C, D | AYE | — |
| 6FFA | FMDV Leader protease bound to substrate ISG15 | x-ray diffraction | B | — | 2 (best 0.71) |
| 6FFA | Fmdv leader protease bound to substrate ISG15 | x-ray diffraction | B | AYE | — |
| 6XA9 | SARS CoV-2 PLpro in complex with ISG15 C-terminal domain propargylamide | x-ray diffraction | B, D, F | — | 11 (best 0.77) |
| 6XA9 | SARS cov-2 plpro in complex with ISG15 C-terminal domain propargylamide | x-ray diffraction | B, D, F | AYE | — |
| 7RBS | The crystal structure of papain-like protease of SARS cov-2, C111S mutant, in complex with human… | x-ray diffraction | B, D, F, H, J | — | — |
| 7S6P | The crystal structure of human ISG15 | x-ray diffraction | A, B, C, D, E, F | — | — |
| 8SEA | Cryo-EM structure of a double loaded human UBA7-UBE2L6-ISG15 thioester mimetic complex (Form 1) | electron microscopy | B, D | AMP | 12 (best 0.80) |
| 8SV8 | Cryo-EM structure of a double loaded human UBA7-UBE2L6-ISG15 thioester mimetic complex from a… | electron microscopy | B, D | AMP | 11 (best 0.81) |
| P05161 | AlphaFold monomer V2.0 prediction for ubiquitin-like protein ISG15 (P05161) | — | — | — |
Ligands
Elsewhere
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