MolNFT v1 · #169384 · protein
SARS cov-2 plpro in complex with ISG15 C-terminal domain propargylamide
6XA9: “SARS cov-2 plpro in complex with ISG15 C-terminal domain propargylamide”. X-ray diffraction, 2 ligands (AYE, ZN). MolNFT v1 #169384 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6XA9
- Type
- protein
- Length
- 1,168 residues
- Chains
- 6
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P0DTD1, P05161
- Ligands
- AYE, ZN
Structure
x-ray diffraction · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, C | — | protein | 313 | — | P0DTD1 |
| B | — | protein | 79 | — | P05161 |
| D, F | — | protein | 78 | — | P05161 |
| E | — | protein | 307 | — | P0DTD1 |
Ligands and binding sites
- AYE · prop-2-en-1-amine · ligand · 3 copies · chains A, B, C, D, E, F
- ZN · Zinc ion · metal · 3 copies · chains A, C, E
- GOL · Glycerol · additive · 8 copies · chains A, C, E
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6XA9 · SARS CoV-2 PLpro in complex with ISG15 C-terminal domain propargylamide · the same entry in another collection · chain F against F, TM-score 1.00
- P05161 · AlphaFold monomer V2.0 prediction for ubiquitin-like protein ISG15 (P05161) · a predicted model of the same protein · chain B against A, TM-score 0.96
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0DTD1
- Every structure of UniProt P05161
- Elsewhere: RCSB PDB 6XA9 · PDBe 6XA9 · UniProt P0DTD1 · UniProt P05161
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