UniProt P02881
Monellin chain B,Monellin chain A (P02881)
Monellin chain B,Monellin chain A (UniProt P02881): 50 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 15 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P02881
- Protein
- Monellin chain B,Monellin chain A
- Experimental structures
- 50
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 15 · 7 records with a druggable one
Structures
51 records of P02881 in the MolNFT archive: 50 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1FA3 | Solution structure of mnei, a sweet protein | solution nmr | A | — | — |
| 1FA3 | Solution structure of mnei, a sweet protein | solution nmr | A | — | — |
| 1FUW | Solution structure and backbone dynamics of a double mutant single-chain MONELLIN(SCM) determined… | solution nmr | A | — | — |
| 1FUW | Solution structure and backbone dynamics of a double mutant single- chain MONELLIN(SCM) determined… | solution nmr | A | — | — |
| 1IV7 | Crystal Structure of Single Chain Monellin | x-ray diffraction | A, B | — | 1 (best 0.64) |
| 1IV7 | Crystal structure of single chain monellin | x-ray diffraction | A, B | — | — |
| 1IV9 | Crystal Structure of Single Chain Monellin | x-ray diffraction | A, B | — | 1 (best 0.61) |
| 1IV9 | Crystal structure of single chain monellin | x-ray diffraction | A, B | — | — |
| 1KRL | Crystal Structure of Racemic DL-monellin in P-1 | x-ray diffraction | A, C | — | — |
| 1KRL | Crystal structure of racemic dl-monellin in P-1 | x-ray diffraction | A, C | — | — |
| 1M9G | Solution structure of G16A-MNEI, a structural mutant of single chain monellin MNEI | solution nmr | A | — | 1 (best 0.36) |
| 1M9G | Solution structure of G16A-mnei, a structural mutant of single chain monellin mnei | solution nmr | A | — | — |
| 1MNL | High-resolution solution structure of a sweet protein single-chain monellin (scm) determined by… | solution nmr | A | — | — |
| 1MNL | High-resolution solution structure of a sweet protein single-chain monellin (scm) determined by… | solution nmr | A | — | — |
| 2O9U | Monellin (MNEI) at 1.15 resolution | x-ray diffraction | X | SO4 | — |
| 2O9U | Monellin (mnei) at 1.15 resolution | x-ray diffraction | X | — | — |
| 3MON | Crystal structures of two intensely sweet proteins | x-ray diffraction | A, C, E, G | — | — |
| 3MON | Crystal structures of two intensely sweet proteins | x-ray diffraction | A, C, E, G | — | — |
| 3PXM | Reduced sweetness of a monellin (MNEI) mutant results from increased protein flexibility and… | x-ray diffraction | A, B | — | — |
| 3PXM | Reduced sweetness of a monellin (mnei) mutant results from increased protein flexibility and… | x-ray diffraction | A, B | — | — |
| 3PYJ | Reduced sweetness of a monellin (MNEI) mutant results from increased protein flexibility and… | x-ray diffraction | A | — | — |
| 3PYJ | Reduced sweetness of a monellin (mnei) mutant results from increased protein flexibility and… | x-ray diffraction | A | — | — |
| 3Q2P | Reduced sweetness of a monellin (MNEI) mutant results from increased protein flexibility and… | x-ray diffraction | A, B, C, D | — | — |
| 3Q2P | Reduced sweetness of a monellin (mnei) mutant results from increased protein flexibility and… | x-ray diffraction | A, B, C, D | — | — |
| 4MON | Orthorhombic monellin | x-ray diffraction | A, C | — | — |
| 4MON | Orthorhombic monellin | x-ray diffraction | A, C | — | — |
| 5LC6 | Crystal structure of a single chain monellin mutant: Q28K/C41S/Y65R-MNEI | x-ray diffraction | A, B | SO4 | — |
| 5LC6 | Crystal structure of a single chain monellin mutant: Q28K/C41S/Y65R- mnei | x-ray diffraction | A, B | SO4 | — |
| 5LC7 | Crystal structure of a single chain monellin mutant: E23Q/Q28K/C41S/Y65R-MNEI | x-ray diffraction | A, B | — | — |
| 5LC7 | Crystal structure of a single chain monellin mutant: E23Q/Q28K/C41S/Y65R-mnei | x-ray diffraction | A, B | — | — |
| 5O7K | Crystal structure of a single chain monellin mutant (Y65R) pH 2.0 | x-ray diffraction | A, B | SO4 | — |
| 5O7K | Crystal structure of a single chain monellin mutant (Y65R) pH 2.0 | x-ray diffraction | A, B | SO4 | — |
| 5O7Q | Crystal structure of a single chain monellin mutant (Y65R) pH 5.5 | x-ray diffraction | A, B | SO4 | — |
| 5O7Q | Crystal structure of a single chain monellin mutant (Y65R) pH 5.5 | x-ray diffraction | A, B | SO4 | — |
| 5O7R | Crystal structure of a single chain monellin mutant (Y65R) pH 6.5 | x-ray diffraction | A, B | SO4 | — |
| 5O7R | Crystal structure of a single chain monellin mutant (Y65R) pH 6.5 | x-ray diffraction | A, B | SO4 | — |
| 5O7S | Crystal structure of a single chain monellin mutant (Y65R) pH 8.3 | x-ray diffraction | A, B | SO4 | — |
| 5O7S | Crystal structure of a single chain monellin mutant (Y65R) pH 8.3 | x-ray diffraction | A, B | SO4 | — |
| 5XFU | Domain swapped dimer crystal structure of loop1 deletion mutant in Single-chain Monellin | x-ray diffraction | A, B, C, D, E | — | 1 (best 0.46) |
| 5XFU | Domain swapped dimer crystal structure of LOOP1 deletion mutant in single-chain monellin | x-ray diffraction | A, B, C, D, E | — | — |
| 5Z1P | Structural basis of the improved sweetness and stability of the single-chain sweet-tasting protein… | x-ray diffraction | A, B, C, D | — | 3 (best 0.63) |
| 5Z1P | Structural basis of the improved sweetness and stability of the single-chain sweet-tasting protein… | x-ray diffraction | A, B, C, D | — | — |
| 6LAY | Domain-swapped dimer structure of a Single-chain Monellin loop1-delta4-QVVAG mutant | x-ray diffraction | A, B | — | — |
| 6LAY | Domain-swapped dimer structure of a single-chain monellin LOOP1- DELTA4-qvvag mutant | x-ray diffraction | A, B | — | — |
| 7VWW | X-ray structure of a domain-swapped poly-glutamine Monellin mutant | x-ray diffraction | A, B, C, D, E, F, G, H | — | 5 (best 0.69) |
| 8JZ0 | Crystal structure of a single-chain monellin mutant C41A | x-ray diffraction | A, B | — | 1 (best 0.56) |
| 8JZ1 | Crystal structure of a single-chain monellin mutant C41V | x-ray diffraction | B, A | — | 1 (best 0.64) |
| 8Q0R | X-ray structure of MNEI mutant Mut9 (E23A, C41A, Y65R, S76Y) | x-ray diffraction | AAA, BBB | SO4 | — |
| 8Q0S | X-ray structure of the single chain monellin derivative MNEI | x-ray diffraction | AAA, BBB | NA | — |
| 8TM8 | Monomer structure of monellin loop1 mutant (YENKG) | x-ray diffraction | A, B | NA | 1 (best 0.59) |
| P02881 | AlphaFold monomer V2.0 prediction for monellin chain a (P02881) | predicted | A | — | — |
Ligands
Experiment against prediction
- 8Q0S chain AAA against the predicted model P02882: TM-score 0.51, RMSD 0.64 Å
- 8Q0R chain AAA against the predicted model P02882: TM-score 0.50, RMSD 0.78 Å
- 8Q0S chain BBB against the predicted model P02882: TM-score 0.50, RMSD 0.69 Å
- 8JZ1 chain A against the predicted model P02882: TM-score 0.50, RMSD 1.26 Å
- 8Q0R chain BBB against the predicted model P02882: TM-score 0.50, RMSD 0.80 Å
- 8Q0R chain AAA against the predicted model P02881: TM-score 0.45, RMSD 0.68 Å
- 8Q0S chain AAA against the predicted model P02881: TM-score 0.45, RMSD 0.75 Å
- 5Z1P chain A against the predicted model P02882: TM-score 0.50, RMSD 0.62 Å
- 5Z1P chain A against the predicted model P02882: TM-score 0.50, RMSD 0.62 Å
- 5O7R chain A against the predicted model P02882: TM-score 0.50, RMSD 1.15 Å
Elsewhere
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