UniProt P00489
Glycogen phosphorylase, muscle form (P00489)
Glycogen phosphorylase, muscle form (UniProt P00489), EC 2.4.1.1: 419 experimental structures on GenesisL1, 46 ligands bound, 165 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P00489
- Protein
- Glycogen phosphorylase, muscle form
- EC
- 2.4.1.1
- Experimental structures
- 419
- Predicted models
- 0
- Ligands
- 46
- Pockets
- 165 · 12 records with a druggable one
Structures
419 records of P00489 in the MolNFT archive: 419 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1A8I | Spirohydantoin inhibitor of glycogen phosphorylase | x-ray diffraction | A | — | — |
| 1A8I | Spirohydantoin inhibitor of glycogen phosphorylase | x-ray diffraction | A | — | — |
| 1ABB | Control of phosphorylase B conformation by a modified cofactor: crystallographic studies on R-state… | x-ray diffraction | A, B, C, D | — | — |
| 1ABB | Control of phosphorylase B conformation by a modified cofactor: crystallographic studies on R-state… | x-ray diffraction | A, B, C, D | — | — |
| 1AXR | Cooperativity between hydrogen-bonding and charge-dipole interactions in the inhibition of… | x-ray diffraction | A | — | — |
| 1AXR | Cooperativity between hydrogen-bonding and charge-dipole interactions in the inhibition of… | x-ray diffraction | A | — | — |
| 1B4D | Amidocarbamate inhibitor of glycogen phosphorylase | x-ray diffraction | A | — | — |
| 1B4D | Amidocarbamate inhibitor of glycogen phosphorylase | x-ray diffraction | A | — | — |
| 1BX3 | Effects of commonly used cryoprotectants on glycogen phosphorylase activity and structure | x-ray diffraction | A | — | — |
| 1BX3 | Effects of commonly used cryoprotectants on glycogen phosphorylase activity and structure | x-ray diffraction | A | — | — |
| 1C50 | Identification and structural characterization of a novel allosteric binding site of glycogen… | x-ray diffraction | A | — | — |
| 1C50 | Identification and structural characterization of a novel allosteric binding site of glycogen… | x-ray diffraction | A | — | — |
| 1C8K | Flavopiridol inhibits glycogen phosphorylase by binding at the inhibitor site | x-ray diffraction | A | — | — |
| 1C8K | Flavopiridol inhibits glycogen phosphorylase by binding at the inhibitor site | x-ray diffraction | A | — | — |
| 1C8L | Synergistic inhibition of glycogen phosphorylase a by a potential antidiabetic drug and caffeine | x-ray diffraction | A | — | — |
| 1C8L | Synergistic inhibition of glycogen phosphorylase a by a potential antidiabetic drug and caffeine | x-ray diffraction | A | — | — |
| 1E1Y | Flavopiridol inhibits glycogen phosphorylase by binding at the inhibitor site | x-ray diffraction | A | — | — |
| 1E1Y | Flavopiridol inhibits glycogen phosphorylase by binding at the inhibitor site | x-ray diffraction | A | — | — |
| 1FS4 | Structures of glycogen phosphorylase-inhibitor complexes and the implications for structure-based… | x-ray diffraction | A | — | — |
| 1FS4 | Structures of glycogen phosphorylase-inhibitor complexes and the implications for structure-based… | x-ray diffraction | A | — | — |
| 1FTQ | Structures of glycogen phosphorylase-inhibitor complexes and the implications for structure-based… | x-ray diffraction | A | — | — |
| 1FTQ | Structures of glycogen phosphorylase-inhibitor complexes and the implications for structure-based… | x-ray diffraction | A | — | — |
| 1FTW | Structures of glycogen phosphorylase-inhibitor complexes and the implications for structure-based… | x-ray diffraction | A | — | — |
| 1FTW | Structures of glycogen phosphorylase-inhibitor complexes and the implications for structure-based… | x-ray diffraction | A | — | — |
| 1FTY | Structures of glycogen phosphorylase-inhibitor complexes and the implications for structure-based… | x-ray diffraction | A | — | — |
| 1FTY | Structures of glycogen phosphorylase-inhibitor complexes and the implications for structure-based… | x-ray diffraction | A | — | — |
| 1FU4 | Structures of glycogen phosphorylase-inhibitor complexes and the implications for structure-based… | x-ray diffraction | A | — | — |
| 1FU4 | Structures of glycogen phosphorylase-inhibitor complexes and the implications for structure-based… | x-ray diffraction | A | — | — |
| 1FU7 | Structures of glycogen phosphorylase-inhibitor complexes and the implications for structure-based… | x-ray diffraction | A | — | — |
| 1FU7 | Structures of glycogen phosphorylase-inhibitor complexes and the implications for structure-based… | x-ray diffraction | A | — | — |
| 1FU8 | Structures of glycogen phosphorylase-inhibitor complexes and the implications for structure-based… | x-ray diffraction | A | — | — |
| 1FU8 | Structures of glycogen phosphorylase-inhibitor complexes and the implications for structure-based… | x-ray diffraction | A | — | — |
| 1GFZ | Flavopiridol inhibits glycogen phosphorylase by binding at the inhibitor site | x-ray diffraction | A | — | — |
| 1GFZ | Flavopiridol inhibits glycogen phosphorylase by binding at the inhibitor site | x-ray diffraction | A | — | — |
| 1GG8 | Design of inhibitors of glycogen phosphorylase: a study of alpha-and beta-C-glucosides and… | x-ray diffraction | A | — | — |
| 1GG8 | Design of inhibitors of glycogen phosphorylase: a study of alpha-and beta-C-glucosides and… | x-ray diffraction | A | — | — |
| 1GGN | Structures of glycogen phosphorylase-inhibitor complexes and the implications for structure-based… | x-ray diffraction | A | — | — |
| 1GGN | Structures of glycogen phosphorylase-inhibitor complexes and the implications for structure-based… | x-ray diffraction | A | — | — |
| 1GPA | Structural mechanism for glycogen phosphorylase control by phosphorylation and AMP | x-ray diffraction | A, B, C, D | — | — |
| 1GPA | Structural mechanism for glycogen phosphorylase control by phosphorylation and AMP | x-ray diffraction | A, B, C, D | — | — |
| 1GPB | Glycogen phosphorylase B: description of the protein structure | x-ray diffraction | A | — | — |
| 1GPB | Glycogen phosphorylase B: description of the protein structure | x-ray diffraction | A | — | — |
| 1GPY | Crystallographic binding studies on the allosteric inhibitor glucose-6-phosphate to T state… | x-ray diffraction | A | — | — |
| 1GPY | Crystallographic binding studies on the allosteric inhibitor glucose- 6-phosphate to T state… | x-ray diffraction | A | — | — |
| 1H5U | The 1.76 a resolution crystal structure of glycogen phosphorylase B complexed with glucose and… | x-ray diffraction | A | — | — |
| 1H5U | The 1.76 a resolution crystal structure of glycogen phosphorylase B complexed with glucose and… | x-ray diffraction | A | — | — |
| 1HLF | Binding of glucopyranosylidene-spiro-thiohydantoin to glycogen phosphorylase B: kinetic and… | x-ray diffraction | A | — | — |
| 1HLF | Binding of glucopyranosylidene-spiro-thiohydantoin to glycogen phosphorylase B: kinetic and… | x-ray diffraction | A | — | — |
| 1K06 | Crystallographic Binding Study of 100 mM N-benzoyl-N'-beta-D-glucopyranosyl urea to glycogen… | x-ray diffraction | A | — | — |
| 1K06 | Crystallographic binding study of 100 mm N-benzoyl-N'-beta-D- glucopyranosyl urea to glycogen… | x-ray diffraction | A | — | — |
| 1K08 | Crystallographic Binding Study of 10 mM N-benzoyl-N'-beta-D-glucopyranosyl urea to glycogen… | x-ray diffraction | A | — | — |
| 1K08 | Crystallographic binding study of 10 mm N-benzoyl-N'-beta-D- glucopyranosyl urea to glycogen… | x-ray diffraction | A | — | — |
| 1KTI | Binding of 100 mm N-acetyl-N'-beta-D-glucopyranosyl urea to glycogen phosphorylase B: kinetic and… | x-ray diffraction | A | — | — |
| 1KTI | Binding of 100 mm N-acetyl-N'-beta-D-glucopyranosyl urea to glycogen phosphorylase B: kinetic and… | x-ray diffraction | A | — | — |
| 1LWN | Crystal structure of rabbit muscle glycogen phosphorylase a in complex with a potential… | x-ray diffraction | A | — | — |
| 1LWN | Crystal structure of rabbit muscle glycogen phosphorylase a in complex with a potential… | x-ray diffraction | A | — | — |
| 1LWO | Crystal structure of rabbit muscle glycogen phosphorylase a in complex with a potential… | x-ray diffraction | A | — | — |
| 1LWO | Crystal structure of rabbit muscle glycogen phosphorylase a in complex with a potential… | x-ray diffraction | A | — | — |
| 1NOI | Complex of glycogen phosphorylase with a transition state analogue nojirimycin tetrazole and… | x-ray diffraction | A, B, C, D | — | — |
| 1NOI | Complex of glycogen phosphorylase with a transition state analogue nojirimycin tetrazole and… | x-ray diffraction | A, B, C, D | — | — |
359 records more on the page itself.
Ligands
- PLP · Pyridoxal-5'-phosphate · in 55 records
- IMP · Inosinic acid · in 14 records
- AMP · Adenosine monophosphate · in 5 records
- SO4 · Sulfate ion · in 4 records
- KS3 · (2~{R},3~{S},4~{R},5~{R},6~{S})-2-(hydroxymethyl)-6-(3-naphthalen-2-yl-1~{H}-1,2,4-triazol-5-yl)oxane-3,4,5-triol · in 3 records
- 73E · (1S)-1,5-anhydro-1-(5-phenyl-4H-1,2,4-triazol-3-yl)-D-glucitol · in 2 records
- 7LS · 2-[[1-[(2~{R},3~{R},4~{S},5~{S},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]-2-oxidanylidene-pyrimidin-4-yl]amino]-10~{H}-acridin-9-one · in 2 records
- 9L8 · (2~{R},3~{S},4~{R},5~{R},6~{R})-5-azanyl-2-(hydroxymethyl)-6-(3-naphthalen-2-yl-1~{H}-1,2,4-triazol-5-yl)oxane-3,4-diol · in 2 records
- 9LB · (2~{R},3~{S},4~{R},5~{R},6~{R})-5-azanyl-2-(hydroxymethyl)-6-(5-phenyl-4~{H}-1,2,4-triazol-3-yl)oxane-3,4-diol · in 2 records
- 9LE · (2~{R},3~{S},4~{R},5~{R},6~{R})-5-azanyl-2-(hydroxymethyl)-6-(4-naphthalen-2-yl-1~{H}-imidazol-2-yl)oxane-3,4-diol · in 2 records
- CKQ · 4-[4-[5-[(2~{S},3~{R},4~{R},5~{S},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]-4~{H}-1,2,4-triazol-3-yl]phenyl]benzoic acid · in 2 records
- CKW · (2~{R},3~{S},4~{R},5~{R},6~{S})-2-(hydroxymethyl)-6-[5-(4-phenylphenyl)-4~{H}-1,2,4-triazol-3-yl]oxane-3,4,5-triol · in 2 records
- HT8 · (5~{S},7~{R},8~{S},9~{S},10~{R})-7-(hydroxymethyl)-2-naphthalen-2-yl-8,9,10-tris(oxidanyl)-6-oxa-1,3-diazaspiro[4.5]dec-1-en-4-one · in 2 records
- HTW · (5~{S},7~{R},8~{S},9~{S},10~{R})-7-(hydroxymethyl)-2-naphthalen-1-yl-8,9,10-tris(oxidanyl)-6-oxa-1,3-diazaspiro[4.5]dec-1-en-4-one · in 2 records
- JNB · ~{N}-[(2~{R},3~{R},4~{S},5~{S},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]-4-phenyl-benzamide · in 2 records
- KS2 · (2~{R},3~{S},4~{R},5~{R},6~{S})-2-(hydroxymethyl)-6-[5-(4-methylphenyl)-4~{H}-1,2,4-triazol-3-yl]oxane-3,4,5-triol · in 2 records
- KV5 · (2~{R},3~{S},4~{R},5~{R},6~{S})-2-(hydroxymethyl)-6-(2-naphthalen-2-yl-1~{H}-imidazol-4-yl)oxane-3,4,5-triol · in 2 records
- 6MY · (1S)-1,5-anhydro-1-(5-phenyl-1H-imidazol-2-yl)-D-glucitol · in 1 record
- 6NE · (1S)-1,5-anhydro-1-[5-(naphthalen-2-yl)-1H-imidazol-2-yl]-D-glucitol · in 1 record
- 9L2 · (2~{R},3~{S},4~{R},5~{R},6~{R})-5-azanyl-2-(hydroxymethyl)-6-(4-phenyl-1~{H}-imidazol-2-yl)oxane-3,4-diol · in 1 record
- B0W · 4-[5-[(2~{S},3~{R},4~{R},5~{S},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]-4~{H}-1,2,4-triazol-3-yl]benzoic acid · in 1 record
- B0Z · (2~{R},3~{S},4~{R},5~{R},6~{S})-2-(hydroxymethyl)-6-[5-[4-(trifluoromethyl)phenyl]-4~{H}-1,2,4-triazol-3-yl]oxane-3,4,5-triol · in 1 record
- B1H · (1S)-1,5-anhydro-1-(3-{4-[hydroxy(oxo) azaniumyl]phenyl}-1H-1,2,4-triazol-5-yl)-D-glucitol · in 1 record
- B1K · (2~{R},3~{S},4~{R},5~{R},6~{S})-2-(hydroxymethyl)-6-[5-(4-methoxyphenyl)-1~{H}-1,2,4-triazol-3-yl]oxane-3,4, 5-triol · in 1 record
- B1N · (1S)-1,5-anhydro-1-[3-(4-hydroxyphenyl)-1H-1,2,4-triazol-5-yl]-D-glucitol · in 1 record
- B1W · (2~{S},3~{R},4~{R},5~{S},6~{R})-2-[5-(4-aminophenyl)-4~{H}-1,2,4-triazol-3-yl]-6-(hydroxymethyl)oxane-3,4, 5-triol · in 1 record
- CFF · Caffeine · in 1 record
- CGG · Chlorogenic acid · in 1 record
- CJW · 6-[5-[(2~{S},3~{R},4~{R},5~{S},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]-1~{H}-1,2,4-triazol-3-yl]naphthalene-2-carboxylic acid · in 1 record
- CKZ · (2~{S},3~{R},4~{R},5~{S},6~{R})-2-[5-(9~{H}-fluoren-2-yl)-4~{H}-1,2,4-triazol-3-yl]-6-(hydroxymethyl)oxane-3,4,5-triol · in 1 record
Elsewhere
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