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Ligand · G6P

G6P · 6-O-phosphono-alpha-D-glucopyranose

G6P, 6-O-phosphono-alpha-D-glucopyranose (C6 H13 O9 P, 260.1 g/mol), in the MolNFT structures on GenesisL1: bound in 47 records (35 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands…

Component
G6P
Formula
C6 H13 O9 P
Class
sugar
Structures
47
PDB entries
35

Binding sites

G6P in 47 structures; the first of them:

  • 5JIO · Structure of Mycobacterium thermoresistibile trehalose-6-phosphate synthase ternary… · G6P A502 · binds ARG18, PRO37, GLY38, GLY39, LEU40, TYR90, ASN95, TRP99 and 8 more
  • 5OLY · 5-fluorotryptophan labeled beta-phosphoglucomutase in a closed conformation, monoclinic… · G6P A303 · binds ASP8, ASP10, HIS20, LEU44, LYS45, GLY46, VAL47, SER48 and 7 more
  • 5WSA · Pyruvate kinase (PYK) from Mycobacterium tuberculosis in complex with Oxalate and… · G6P A501 · binds LEU233, GLU267, ASN268, HIS345, PRO347, ARG348, THR349, GLY352 and 2 more
  • 5WSC · Crystal of pyruvate kinase (PYK) from Mycobacterium tuberculosis in complex with Oxalate… · G6P A502 · binds LEU233, GLU267, ASN268, LYS270, HIS345, PRO347, ARG348, THR349 and 3 more
  • 6KEV · Reduced phosphoribulokinase from Synechococcus elongatus PCC 7942 complexed with… · G6P A402 · binds ASP42, HIS45, ARG49, ARG52, THR58, ALA59, TYR88, HIS90 and 1 more
  • 6LKG · two-component system protein mediate signal transduction · G6P A401 · binds PRO36, TYR37, SER63, THR64, GLY85, GLY86, MET126, THR165 and 6 more
  • 6LKH · Two-component system protein mediate signal transduction · G6P A401 · binds PRO36, TYR37, SER63, THR64, GLY85, GLY86, MET126, THR165 and 6 more
  • 6MGI · Photosynthetic phosphoenolpyruvate carboxylase isoenzyme from maize complexed with the… · G6P A1002 · binds ARG183, ARG184, SER185, ARG231, ASP239, GLU360, PHE361, TRP362 and 2 more
  • 6NNP · Xanthomonas citri Dephospho-PGM in complex with glucose-6-phosphate · G6P A502 · binds TYR9, ARG280, GLY302, HIS303, GLU320, SER322, HIS324, TYR326 and 5 more
  • 6NNS · Xanthomonas citri Phospho-PGM in complex with glucose-6-phosphate · G6P A502 · binds TYR9, ARG280, GLY302, HIS303, GLU320, SER322, HIS324, TYR326 and 5 more
  • 6SNQ · Crystal structures of human PGM1 isoform 2 · G6P A602 · binds SER38, SEP135, ARG311, THR375, GLY376, TRP377, GLU394, SER396 and 5 more
  • 6TDF · Crystal structure of Aspergillus fumigatus Glucosamine-6-phosphate N-acetyltransferase 1… · G6P A203 · binds LEU69, THR70, GLU129, ASP130, ASP165, CYS166, TYR189
  • 7Q0S · Human GYS1-GYG1 complex inhibited-like state bound to glucose-6-phosphate · G6P A801 · binds GLN294, HIS297, LYS301, HIS501, ARG582, ARG586
  • 5K44 · Structure of mycobacterium thermoresistibile trehalose-6-phosphate synthase in a complex… · G6P B2 · binds TYR90, ASN95, TRP99, TYR145, GLN146, ARG286, ARG324
  • 5OLY · 5-fluorotryptophan labeled beta-phosphoglucomutase in a closed conformation, monoclinic… · G6P A303 · binds ASP8, ASP10, HIS20, LEU44, LYS45, GLY46, VAL47, SER48 and 7 more
  • 5SUK · G6P bound activated state of yeast glycogen synthase 2 · G6P A901 · binds GLN283, ASN284, HIS286, ALA287, LYS290, HIS500, ARG580, ARG583 and 2 more
  • 5UW0 · Activated state YGSY2P in complex with udp-2-fluoro-2-deoxy-glucose · G6P A802 · binds GLN283, ASN284, HIS286, ALA287, LYS290, HIS500, ARG580, ARG583 and 3 more
  • 5UW1 · Activated state YGSY2P in complex with udp-galactose · G6P A802 · binds GLN283, ASN284, HIS286, ALA287, LYS290, HIS500, ARG580, ARG583 and 3 more

Residues it binds most

ARG 117, HIS 110, GLY 75, THR 62, LYS 82, TYR 57, SER 50, GLU 72, ASN 77, ALA 63 (residue and the binding sites it lines).

Found with

  • MG · Magnesium ion
  • PO4 · Phosphate ion
  • UDP · Uridine-5'-diphosphate
  • EDO · 1,2-ethanediol
  • OXL · Oxalate ion
  • GOL · Glycerol
  • ACO · Acetyl coenzyme *A
  • ADP · Adenosine-5'-diphosphate
  • AMP · Adenosine monophosphate
  • K · Potassium ion
  • GLC · alpha-D-glucopyranose
  • MGF · Trifluoromagnesate

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