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Ligand · NTZ

NTZ · Nojirimycine tetrazole

NTZ, Nojirimycine tetrazole (C6 H10 N4 O4, 202.2 g/mol), in the MolNFT structures on GenesisL1: bound in 12 records (6 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with…

Component
NTZ
Formula
C6 H10 N4 O4
Class
ligand
Structures
12
PDB entries
6

Binding sites

NTZ in 12 structures; the first of them:

  • 1E6Q · MYROSINASE FROM SINAPIS ALBA with the bound transition state analogue gluco-tetrazole · NTZ M999 · binds GLN39, HIS141, TRP142, ASN186, GLN187, ILE257, ASN328, TYR330 and 5 more
  • 1NOI · Complex of glycogen phosphorylase with a transition state analogue nojirimycin tetrazole… · NTZ A998 · binds GLY135, LEU136, LEU139, HIS377, THR378, VAL455, ASN484, ARG569 and 6 more
  • 1NOJ · Complex of glycogen phosphorylase with a transition state analogue nojirimycin tetrazole… · NTZ A998 · binds GLY135, LEU136, LEU139, ASN284, HIS377, THR378, VAL455, ASN484 and 7 more
  • 1NOK · Complex of glycogen phosphorylase with a transition state analogue nojirimycin tetrazole… · NTZ A998 · binds GLY135, LEU136, LEU139, ASN284, HIS377, VAL455, ASN484, TYR573 and 5 more
  • 1V08 · Crystal structure of the Zea maze beta-glucosidase-1 in complex with gluco-tetrazole · NTZ A1502 · binds GLN38, HIS142, TRP143, ASN190, ASP191, ASN331, TYR333, TRP378 and 5 more
  • 2J7B · Beta-glucosidase from Thermotoga maritima in complex with gluco- tetrazole · NTZ A1446 · binds GLN20, HIS121, TRP122, ASN165, GLU166, ASN293, TYR295, TRP324 and 5 more
  • 1E6Q · Myrosinase from sinapis alba with the bound transition state analogue gluco-tetrazole · NTZ M999 · binds GLN39, HIS141, TRP142, ASN186, GLN187, ILE257, ASN328, TYR330 and 5 more
  • 1NOI · Complex of glycogen phosphorylase with a transition state analogue nojirimycin tetrazole… · NTZ A998 · binds GLY135, LEU136, LEU139, HIS377, THR378, VAL455, ASN484, ARG569 and 6 more
  • 1NOJ · Complex of glycogen phosphorylase with a transition state analogue nojirimycin tetrazole… · NTZ A998 · binds GLY135, LEU136, LEU139, ASN284, HIS377, THR378, VAL455, ASN484 and 7 more
  • 1NOK · Complex of glycogen phosphorylase with a transition state analogue nojirimycin tetrazole… · NTZ A998 · binds GLY135, LEU136, LEU139, ASN284, HIS377, VAL455, ASN484, TYR573 and 5 more
  • 1V08 · Crystal structure of the zea maze beta-glucosidase-1 in complex with gluco-tetrazole · NTZ A1502 · binds GLN38, HIS142, TRP143, ASN190, ASP191, ASN331, TYR333, TRP378 and 5 more
  • 2J7B · Beta-glucosidase from thermotoga maritima in complex with gluco-tetrazole · NTZ A1446 · binds GLN20, HIS121, TRP122, ASN165, GLU166, ASN293, TYR295, TRP324 and 5 more

Residues it binds most

TRP 14, GLU 26, ASN 22, TYR 22, GLY 12, LEU 12, THR 16, HIS 22, PHE 10, ASP 14 (residue and the binding sites it lines).

Found with

  • PLP · Pyridoxal-5'-phosphate
  • PO4 · Phosphate ion
  • CA · Calcium ion
  • ZN · Zinc ion
  • BMA · beta-D-mannopyranose
  • FUC · alpha-L-fucopyranose
  • MAN · alpha-D-mannopyranose
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose
  • XYP · beta-D-xylopyranose
  • SO4 · Sulfate ion
  • ACT · Acetate ion
  • GOL · Glycerol

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