UniProt P00405
Cytochrome c oxidase subunit 2 (P00405)
Cytochrome c oxidase subunit 2 (UniProt P00405), EC 7.1.1.9: 5 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- P00405
- Protein
- Cytochrome c oxidase subunit 2
- EC
- 7.1.1.9
- Experimental structures
- 5
- Predicted models
- 1
- Ligands
- 5
- Pockets
- 2 · 1 record with a druggable one
Structures
6 records of P00405 in the MolNFT archive: 5 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7O37 | Murine supercomplex CIII2CIV in the assembled locked conformation | electron microscopy | b | HEA, PC1, MG, 3PE, CUA | — |
| 7O3C | Murine supercomplex CIII2CIV in the mature unlocked conformation | electron microscopy | b | HEA, MG, 3PE, CUA | — |
| 7O3C | Murine supercomplex CIII2CIV in the mature unlocked conformation | electron microscopy | b | HEA, MG, 3PE, CUA | — |
| 7O3E | Murine supercomplex CIII2CIV in the intermediate locked conformation | electron microscopy | b | HEA, PC1, MG, 3PE, CUA | — |
| 8PW6 | C respirasome from murine liver | electron microscopy | o | HEA, 3PE, MG, CUA | 2 (best 0.92) |
| P00405 | AlphaFold monomer V2.0 prediction for cytochrome C oxidase subunit 2 (P00405) | predicted | A | — | — |
Ligands
Experiment against prediction
- 7O37 chain b against the predicted model P00405: TM-score 0.99, RMSD 0.68 Å
- 7O3E chain b against the predicted model P00405: TM-score 0.98, RMSD 0.73 Å
- 8PW6 chain o against the predicted model P00405: TM-score 0.98, RMSD 0.76 Å
- 7O3C chain b against the predicted model P00405: TM-score 0.98, RMSD 0.85 Å
- 7O3C chain b against the predicted model P00405: TM-score 0.98, RMSD 0.85 Å
Elsewhere
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