UniProt P00157
Cytochrome b (P00157)
Cytochrome b (UniProt P00157): 72 experimental structures and 1 predicted model on GenesisL1, 24 ligands bound, 143 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P00157
- Protein
- Cytochrome b
- Experimental structures
- 72
- Predicted models
- 1
- Ligands
- 24
- Pockets
- 143 · 13 records with a druggable one
Structures
73 records of P00157 in the MolNFT archive: 72 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1BE3 | Cytochrome BC1 complex from bovine | x-ray diffraction | C | — | — |
| 1BE3 | Cytochrome BC1 complex from bovine | x-ray diffraction | C | — | — |
| 1BGY | Cytochrome BC1 complex from bovine | x-ray diffraction | C, O | — | — |
| 1BGY | Cytochrome BC1 complex from bovine | x-ray diffraction | C, O | — | — |
| 1L0L | structure of bovine mitochondrial cytochrome bc1 complex with a bound fungicide famoxadone | x-ray diffraction | C | — | — |
| 1L0L | Structure of bovine mitochondrial cytochrome BC1 complex with a bound fungicide famoxadone | x-ray diffraction | C | — | — |
| 1L0N | native structure of bovine mitochondrial cytochrome bc1 complex | x-ray diffraction | C | — | — |
| 1L0N | Native structure of bovine mitochondrial cytochrome BC1 complex | x-ray diffraction | C | — | — |
| 1NTK | Crystal Structure of Mitochondrial Cytochrome bc1 in Complex with Antimycin A1 | x-ray diffraction | C | — | — |
| 1NTK | Crystal structure of mitochondrial cytochrome BC1 in complex with antimycin A1 | x-ray diffraction | C | — | — |
| 1NTM | Crystal Structure of Mitochondrial Cytochrome bc1 Complex at 2.4 Angstrom | x-ray diffraction | C | — | — |
| 1NTM | Crystal structure of mitochondrial cytochrome BC1 complex at 2.4 ångström | x-ray diffraction | C | — | — |
| 1NTZ | Crystal Structure of Mitochondrial Cytochrome bc1 Complex Bound with Ubiqui | x-ray diffraction | C | — | — |
| 1NTZ | Crystal structure of mitochondrial cytochrome BC1 complex bound with ubiquinone | x-ray diffraction | C | — | — |
| 1NU1 | Crystal Structure of Mitochondrial Cytochrome bc1 Complexed with 2-nonyl-4-hydroxyquinoline N-oxide… | x-ray diffraction | C | — | — |
| 1NU1 | Crystal structure of mitochondrial cytochrome BC1 complexed with 2- nonyl-4-hydroxyquinoline… | x-ray diffraction | C | — | — |
| 1PP9 | Bovine cytochrome bc1 complex with stigmatellin bound | x-ray diffraction | C, P | — | — |
| 1PP9 | Bovine cytochrome BC1 complex with stigmatellin bound | x-ray diffraction | C, P | — | — |
| 1PPJ | Bovine cytochrome bc1 complex with stigmatellin and antimycin | x-ray diffraction | C, P | — | — |
| 1PPJ | Bovine cytochrome BC1 complex with stigmatellin and antimycin | x-ray diffraction | C, P | — | — |
| 1QCR | Crystal structure of bovine mitochondrial cytochrome BC1 complex, alpha carbon atoms only | x-ray diffraction | C | — | — |
| 1QCR | Crystal structure of bovine mitochondrial cytochrome BC1 complex, alpha carbon atoms only | x-ray diffraction | C | — | — |
| 1SQB | Crystal Structure Analysis of Bovine Bc1 with Azoxystrobin | x-ray diffraction | C | — | — |
| 1SQB | Crystal structure analysis of bovine BC1 with azoxystrobin | x-ray diffraction | C | — | — |
| 1SQP | Crystal Structure Analysis of Bovine Bc1 with Myxothiazol | x-ray diffraction | C | — | — |
| 1SQP | Crystal structure analysis of bovine BC1 with myxothiazol | x-ray diffraction | C | — | — |
| 1SQQ | Crystal Structure Analysis of Bovine Bc1 with Methoxy Acrylate Stilbene (MOAS) | x-ray diffraction | C | — | — |
| 1SQQ | Crystal structure analysis of bovine BC1 with methoxy acrylate stilbene (moas) | x-ray diffraction | C | — | — |
| 1SQV | Crystal Structure Analysis of Bovine Bc1 with UHDBT | x-ray diffraction | C | — | — |
| 1SQV | Crystal structure analysis of bovine BC1 with uhdbt | x-ray diffraction | C | — | — |
| 1SQX | Crystal Structure Analysis of Bovine Bc1 with Stigmatellin A | x-ray diffraction | C | — | — |
| 1SQX | Crystal structure analysis of bovine BC1 with stigmatellin a | x-ray diffraction | C | — | — |
| 2A06 | Bovine cytochrome bc1 complex with stigmatellin bound | x-ray diffraction | C, P | — | — |
| 2A06 | Bovine cytochrome BC1 complex with stigmatellin bound | x-ray diffraction | C, P | — | — |
| 2FYU | Crystal structure of bovine heart mitochondrial bc1 with jg144 inhibitor | x-ray diffraction | C | — | — |
| 2FYU | Crystal structure of bovine heart mitochondrial BC1 with JG144 inhibitor | x-ray diffraction | C | — | — |
| 2YBB | Fitted model for bovine mitochondrial supercomplex I1III2IV1 by single particle cryo-EM (EMD-1876) | electron microscopy | C, c | — | — |
| 2YBB | Fitted model for bovine mitochondrial supercomplex I1III2IV1 by single particle cryo-EM (emd-1876) | electron microscopy | C, c | — | — |
| 4D6T | Cytochrome bc1 bound to the 4(1H)-pyridone GW844520 | x-ray diffraction | C, P | — | — |
| 4D6T | Cytochrome BC1 bound to the 4(1H)-pyridone GW844520 | x-ray diffraction | C, P | — | — |
| 4D6U | Cytochrome bc1 bound to the 4(1H)-pyridone GSK932121 | x-ray diffraction | C, P | — | — |
| 4D6U | Cytochrome BC1 bound to the 4(1H)-pyridone GSK932121 | x-ray diffraction | C, P | — | — |
| 5GPN | Architecture of mammalian respirasome | electron microscopy | C, O | HEM | 3 (best 0.85) |
| 5KLV | Structure of bos taurus cytochrome bc1 with fenamidone inhibited | x-ray diffraction | C | 6PE, CDL, HEM, FNM, 8PE, CL | — |
| 5KLV | Structure of bos taurus cytochrome BC1 with fenamidone inhibited | x-ray diffraction | C | 6PE, CDL, HEM, FNM, 8PE, CL | — |
| 5LUF | Cryo-EM of bovine respirasome | electron microscopy | b, o | HEM | — |
| 5LUF | Cryo-EM of bovine respirasome | electron microscopy | b, o | HEM | — |
| 5NMI | Cytochrome bc1 bound to the inhibitor MJM170 | x-ray diffraction | C, P | HEM, MJM, PEE, CDL | — |
| 5NMI | Cytochrome BC1 bound to the inhibitor MJM170 | x-ray diffraction | C, P | HEM, MJM, PEE, CDL | — |
| 5OKD | Crystal structure of bovine cytochrome BC1 in complex with inhibitor SCR0911. | x-ray diffraction | C | 6PE, CDL, HEM, 9XE, PEE | — |
| 6FO0 | CryoEM structure of bovine cytochrome bc1 in complex with the anti-malarial compound GSK932121 | electron microscopy | P, C | HEM, G8U | 13 (best 0.85) |
| 6FO0 | Cryoem structure of bovine cytochrome BC1 in complex with the anti- malarial compound GSK932121 | electron microscopy | P, C | HEM, G8U | — |
| 6FO2 | CryoEM structure of bovine cytochrome bc1 with no ligand bound | electron microscopy | P, C | HEM | 13 (best 0.85) |
| 6FO2 | Cryoem structure of bovine cytochrome BC1 with no ligand bound | electron microscopy | P, C | HEM | — |
| 6FO6 | CryoEM structure of bovine cytochrome bc1 in complex with the anti-malarial inhibitor SCR0911 | electron microscopy | C, P | HEM, DY2 | 16 (best 0.83) |
| 6FO6 | Cryoem structure of bovine cytochrome BC1 in complex with the anti- malarial inhibitor SCR0911 | electron microscopy | C, P | HEM, DY2 | — |
| 6HAW | Crystal structure of bovine cytochrome bc1 in complex with 2-pyrazolyl quinolone inhibitor WDH2G7 | x-ray diffraction | C | 6PE, PO4, CDL, HEM, PEE, FX2 | 12 (best 0.84) |
| 6HAW | Crystal structure of bovine cytochrome BC1 in complex with 2-pyrazolyl quinolone inhibitor WDH2G7 | x-ray diffraction | C | 6PE, PO4, CDL, HEM, PEE, FX2 | — |
| 6NHG | Rhodobacter sphaeroides Mitochondrial respiratory chain complex | x-ray diffraction | C | 6PE, CDL, HEM, AZO, 8PE, MC3 | 11 (best 0.81) |
| 6NHG | Rhodobacter sphaeroides mitochondrial respiratory chain complex | x-ray diffraction | C | 6PE, CDL, HEM, AZO, 8PE, MC3 | — |
13 records more on the page itself.
Ligands
- HEM · Protoporphyrin IX containing Fe · in 30 records
- CDL · Cardiolipin · in 17 records
- 6PE · 1,2-dihexanoyl-sn-glycero-3-phosphoethanolamine · in 15 records
- PEE · 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine · in 12 records
- PO4 · Phosphate ion · in 7 records
- 8PE · (2R)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(tetradecanoyloxy)propyl octadecanoate · in 5 records
- PX4 · 1,2-dimyristoyl-sn-glycero-3-phosphocholine · in 5 records
- CL · Chloride ion · in 3 records
- PEF · Di-palmitoyl-3-sn-phosphatidylethanolamine · in 3 records
- AZO · Methyl (2Z)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyacrylate · in 2 records
- DY2 · 7-methoxy-3-methyl-2-[5-[4-(trifluoromethyloxy) phenyl]pyridin-3-yl]quinolin-4-ol · in 2 records
- FNM · (5S)-5-methyl-2-(methylsulfanyl)-5-phenyl-3-(phenylamino)-3,5-dihydro-4H-imidazol-4-one · in 2 records
- FX2 · 7-methoxy-3-methyl-2-[1-[[4-(trifluoromethyloxy) phenyl]methyl]pyrazol-4-yl]-3~{H}-quinolin-4-one · in 2 records
- G8U · 3-chloro-6-(hydroxymethyl)-2-methyl-5-{4-[3-(trifluoromethoxy)phenoxy]phenyl}pyridin-4-ol · in 2 records
- I2Q · 3-methyl-2-[4-[[4-(trifluoromethoxy) phenyl]methyl]phenyl]-1H-quinolin-4-one · in 2 records
- JHB · 7-chloranyl-3-methyl-2-[4-[[4-(trifluoromethyloxy) phenyl]methyl]phenyl]-1~{H}-quinolin-4-one · in 2 records
- JHE · 3-methyl-1-oxidanyl-2-[4-[[4-(trifluoromethyloxy) phenyl]methyl]phenyl]quinolin-4-one · in 2 records
- MC3 · 1,2-dimyristoyl-rac-glycero-3-phosphocholine · in 2 records
- MJM · (4aS)-2-methyl-3-(4-phenoxyphenyl)-5,6,7,8-tetrahydroquinolin-4(4aH)-one · in 2 records
- PX6 · 1,2-dipalmitoyl-sn-glycero-3-phosphate · in 2 records
- 9XE · 7-methoxy-3-methyl-2-[5-[4-(trifluoromethyloxy) phenyl]pyridin-3-yl]-1~{H}-quinolin-4-one · in 1 record
- JAG · 2-methyl-3-[4-[4-(trifluoromethyloxy)phenoxy]phenyl]-5, 6,7,8-tetrahydro-3~{H}-quinolin-4-one · in 1 record
- JGW · 2-methyl-3-[4-[[4-(trifluoromethyloxy) phenyl]methyl]phenyl]-3~{H}-quinolin-4-one · in 1 record
- PQU · (5S)-3-anilino-5-methyl-5-(6-phenoxypyridin-3-yl)-1,3-oxazolidine-2,4-dione · in 1 record
Experiment against prediction
- 6ZFU chain C against the predicted model P00157: TM-score 1.00, RMSD 0.36 Å
- 6ZFU chain C against the predicted model P00157: TM-score 1.00, RMSD 0.36 Å
- 6XVF chain C against the predicted model P00157: TM-score 1.00, RMSD 0.38 Å
- 6ZFS chain C against the predicted model P00157: TM-score 1.00, RMSD 0.38 Å
- 5OKD chain C against the predicted model P00157: TM-score 1.00, RMSD 0.39 Å
- 5NMI chain C against the predicted model P00157: TM-score 1.00, RMSD 0.40 Å
- 5NMI chain C against the predicted model P00157: TM-score 1.00, RMSD 0.40 Å
- 5NMI chain P against the predicted model P00157: TM-score 1.00, RMSD 0.40 Å
- 5NMI chain P against the predicted model P00157: TM-score 1.00, RMSD 0.40 Å
- 1NTM chain C against the predicted model P00157: TM-score 1.00, RMSD 0.41 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.