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MolNFT v1 · #149034 · protein

Cryoem structure of bovine cytochrome BC1 in complex with the anti- malarial inhibitor SCR0911

6FO6: “Cryoem structure of bovine cytochrome BC1 in complex with the anti- malarial inhibitor SCR0911”. Electron microscopy, 3 ligands (HEM, DY2, HEC). MolNFT v1 #149034 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
6FO6
Type
protein
Length
3,868 residues
Chains
18
Method
electron microscopy
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
P13272, P31800, P23004, P00157, P00125, P00129, P13271, P00126, P00130
Ligands
HEM, DY2, HEC

Structure

electron microscopy · 11 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
E, R—protein178—P13272
A, N—protein444—P31800
B—protein414—P23004
C, P—protein370—P00157
D, Q—protein237—P00125
F, S—protein98—P00129
G, T—protein72—P13271
H, U—protein65—P00126
J—protein58—P00130
O—protein411—P23004
W—protein57—P00130

Ligands and binding sites

  • HEM · Protoporphyrin IX containing Fe · ligand · 4 copies · chains C, P
  • DY2 · 7-methoxy-3-methyl-2-[5-[4-(trifluoromethyloxy) phenyl]pyridin-3-yl]quinolin-4-ol · ligand · 2 copies · chains C, P
  • HEC · Heme C · ligand · 2 copies · chains D, Q

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 6FO6 · CryoEM structure of bovine cytochrome bc1 in complex with the anti-malarial inhibitor… · the same entry in another collection · chain N against N, TM-score 1.00

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