UniProt P00129
Cytochrome b-c1 complex subunit 7 (P00129)
Cytochrome b-c1 complex subunit 7 (UniProt P00129), EC 1.10.2.2: 79 experimental structures and 1 predicted model on GenesisL1, 7 ligands bound, 291 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P00129
- Protein
- Cytochrome b-c1 complex subunit 7
- EC
- 1.10.2.2
- Experimental structures
- 79
- Predicted models
- 1
- Ligands
- 7
- Pockets
- 291 · 74 records with a druggable one
Structures
80 records of P00129 in the MolNFT archive: 79 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1BCC | Cytochrome BC1 complex from chicken | x-ray diffraction | F | PEE | 4 (best 0.81) |
| 1BCC | Cytochrome BC1 complex from chicken | x-ray diffraction | F | PEE | 4 (best 0.81) |
| 1BE3 | Cytochrome BC1 complex from bovine | x-ray diffraction | F | — | 3 (best 0.84) |
| 1BE3 | Cytochrome BC1 complex from bovine | x-ray diffraction | F | — | 3 (best 0.84) |
| 1BGY | Cytochrome BC1 complex from bovine | x-ray diffraction | F, R | — | 4 (best 0.85) |
| 1BGY | Cytochrome BC1 complex from bovine | x-ray diffraction | F, R | — | 4 (best 0.85) |
| 1L0L | structure of bovine mitochondrial cytochrome bc1 complex with a bound fungicide famoxadone | x-ray diffraction | F | — | 5 (best 0.84) |
| 1L0L | Structure of bovine mitochondrial cytochrome BC1 complex with a bound fungicide famoxadone | x-ray diffraction | F | — | 5 (best 0.84) |
| 1L0N | native structure of bovine mitochondrial cytochrome bc1 complex | x-ray diffraction | F | — | 4 (best 0.80) |
| 1L0N | Native structure of bovine mitochondrial cytochrome BC1 complex | x-ray diffraction | F | — | 4 (best 0.80) |
| 1NTK | Crystal Structure of Mitochondrial Cytochrome bc1 in Complex with Antimycin A1 | x-ray diffraction | F | — | 4 (best 0.83) |
| 1NTK | Crystal structure of mitochondrial cytochrome BC1 in complex with antimycin A1 | x-ray diffraction | F | — | 4 (best 0.83) |
| 1NTM | Crystal Structure of Mitochondrial Cytochrome bc1 Complex at 2.4 Angstrom | x-ray diffraction | F | — | 3 (best 0.82) |
| 1NTM | Crystal structure of mitochondrial cytochrome BC1 complex at 2.4 ångström | x-ray diffraction | F | — | 3 (best 0.82) |
| 1NTZ | Crystal Structure of Mitochondrial Cytochrome bc1 Complex Bound with Ubiqui | x-ray diffraction | F | — | 5 (best 0.82) |
| 1NTZ | Crystal structure of mitochondrial cytochrome BC1 complex bound with ubiquinone | x-ray diffraction | F | — | 5 (best 0.82) |
| 1NU1 | Crystal Structure of Mitochondrial Cytochrome bc1 Complexed with 2-nonyl-4-hydroxyquinoline N-oxide… | x-ray diffraction | F | — | 4 (best 0.82) |
| 1NU1 | Crystal structure of mitochondrial cytochrome BC1 complexed with 2- nonyl-4-hydroxyquinoline… | x-ray diffraction | F | — | 4 (best 0.82) |
| 1PP9 | Bovine cytochrome bc1 complex with stigmatellin bound | x-ray diffraction | F, S | PO4, PEE, JZR, CDL | 4 (best 0.82) |
| 1PP9 | Bovine cytochrome BC1 complex with stigmatellin bound | x-ray diffraction | F, S | PO4, PEE, JZR, CDL | 4 (best 0.82) |
| 1PPJ | Bovine cytochrome bc1 complex with stigmatellin and antimycin | x-ray diffraction | F, S | PEE, CDL, JZR, PO4 | 4 (best 0.82) |
| 1PPJ | Bovine cytochrome BC1 complex with stigmatellin and antimycin | x-ray diffraction | F, S | PEE, CDL, JZR, PO4 | 4 (best 0.82) |
| 1QCR | Crystal structure of bovine mitochondrial cytochrome BC1 complex, alpha carbon atoms only | x-ray diffraction | F | — | — |
| 1QCR | Crystal structure of bovine mitochondrial cytochrome BC1 complex, alpha carbon atoms only | x-ray diffraction | F | — | — |
| 1SQB | Crystal Structure Analysis of Bovine Bc1 with Azoxystrobin | x-ray diffraction | F | — | 4 (best 0.80) |
| 1SQB | Crystal structure analysis of bovine BC1 with azoxystrobin | x-ray diffraction | F | — | 4 (best 0.80) |
| 1SQQ | Crystal Structure Analysis of Bovine Bc1 with Methoxy Acrylate Stilbene (MOAS) | x-ray diffraction | F | — | 4 (best 0.82) |
| 1SQQ | Crystal structure analysis of bovine BC1 with methoxy acrylate stilbene (moas) | x-ray diffraction | F | — | 4 (best 0.82) |
| 1SQV | Crystal Structure Analysis of Bovine Bc1 with UHDBT | x-ray diffraction | F | — | 4 (best 0.82) |
| 1SQV | Crystal structure analysis of bovine BC1 with uhdbt | x-ray diffraction | F | — | 4 (best 0.82) |
| 1SQX | Crystal Structure Analysis of Bovine Bc1 with Stigmatellin A | x-ray diffraction | F | — | 4 (best 0.82) |
| 1SQX | Crystal structure analysis of bovine BC1 with stigmatellin a | x-ray diffraction | F | — | 4 (best 0.82) |
| 2A06 | Bovine cytochrome bc1 complex with stigmatellin bound | x-ray diffraction | F, S | PO4, UNL, CDL, PEE, JZR | 4 (best 0.82) |
| 2A06 | Bovine cytochrome BC1 complex with stigmatellin bound | x-ray diffraction | F, S | PO4, UNL, CDL, PEE, JZR | 4 (best 0.82) |
| 2FYU | Crystal structure of bovine heart mitochondrial bc1 with jg144 inhibitor | x-ray diffraction | F | — | 4 (best 0.80) |
| 2FYU | Crystal structure of bovine heart mitochondrial BC1 with JG144 inhibitor | x-ray diffraction | F | — | 4 (best 0.80) |
| 2YBB | Fitted model for bovine mitochondrial supercomplex I1III2IV1 by single particle cryo-EM (EMD-1876) | electron microscopy | F, f | CDL | 4 (best 0.82) |
| 2YBB | Fitted model for bovine mitochondrial supercomplex I1III2IV1 by single particle cryo-EM (emd-1876) | electron microscopy | F, f | CDL | 4 (best 0.82) |
| 3BCC | Stigmatellin and antimycin bound cytochrome BC1 complex from chicken | x-ray diffraction | F | — | 4 (best 0.79) |
| 3BCC | Stigmatellin and antimycin bound cytochrome BC1 complex from chicken | x-ray diffraction | F | — | 4 (best 0.79) |
| 4D6T | Cytochrome bc1 bound to the 4(1H)-pyridone GW844520 | x-ray diffraction | F, S | PEE, CDL, PO4 | 4 (best 0.82) |
| 4D6T | Cytochrome BC1 bound to the 4(1H)-pyridone GW844520 | x-ray diffraction | F, S | PEE, CDL, PO4 | 4 (best 0.82) |
| 4D6U | Cytochrome bc1 bound to the 4(1H)-pyridone GSK932121 | x-ray diffraction | F, S | PEE, CDL, PO4 | 4 (best 0.82) |
| 4D6U | Cytochrome BC1 bound to the 4(1H)-pyridone GSK932121 | x-ray diffraction | F, S | PEE, CDL, PO4 | 4 (best 0.82) |
| 5KLV | Structure of bos taurus cytochrome bc1 with fenamidone inhibited | x-ray diffraction | F | 8PE, CDL | 4 (best 0.82) |
| 5KLV | Structure of bos taurus cytochrome BC1 with fenamidone inhibited | x-ray diffraction | F | 8PE, CDL | 4 (best 0.82) |
| 5LUF | Cryo-EM of bovine respirasome | electron microscopy | f, r | — | 5 (best 0.84) |
| 5LUF | Cryo-EM of bovine respirasome | electron microscopy | f, r | — | 5 (best 0.84) |
| 5NMI | Cytochrome bc1 bound to the inhibitor MJM170 | x-ray diffraction | F, S | PEE, CDL | 4 (best 0.83) |
| 5NMI | Cytochrome BC1 bound to the inhibitor MJM170 | x-ray diffraction | F, S | PEE, CDL | 4 (best 0.83) |
| 5OKD | Crystal structure of bovine Cytochrome bc1 in complex with inhibitor SCR0911. | x-ray diffraction | F | CDL, PEE, PO4 | 4 (best 0.82) |
| 5OKD | Crystal structure of bovine cytochrome BC1 in complex with inhibitor SCR0911. | x-ray diffraction | F | CDL, PEE, PO4 | 4 (best 0.82) |
| 6FO0 | CryoEM structure of bovine cytochrome bc1 in complex with the anti-malarial compound GSK932121 | electron microscopy | S, F | — | 4 (best 0.82) |
| 6FO0 | Cryoem structure of bovine cytochrome BC1 in complex with the anti- malarial compound GSK932121 | electron microscopy | S, F | — | 4 (best 0.82) |
| 6FO2 | CryoEM structure of bovine cytochrome bc1 with no ligand bound | electron microscopy | S, F | — | 4 (best 0.83) |
| 6FO2 | Cryoem structure of bovine cytochrome BC1 with no ligand bound | electron microscopy | S, F | — | 4 (best 0.83) |
| 6FO6 | CryoEM structure of bovine cytochrome bc1 in complex with the anti-malarial inhibitor SCR0911 | electron microscopy | F, S | — | 5 (best 0.82) |
| 6FO6 | Cryoem structure of bovine cytochrome BC1 in complex with the anti- malarial inhibitor SCR0911 | electron microscopy | F, S | — | 5 (best 0.82) |
| 6HAW | Crystal structure of bovine cytochrome bc1 in complex with 2-pyrazolyl quinolone inhibitor WDH2G7 | x-ray diffraction | F | CDL, PEE, PO4 | 4 (best 0.83) |
| 6HAW | Crystal structure of bovine cytochrome BC1 in complex with 2-pyrazolyl quinolone inhibitor WDH2G7 | x-ray diffraction | F | CDL, PEE, PO4 | 4 (best 0.83) |
20 records more on the page itself.
Ligands
- CDL · Cardiolipin · in 33 records
- PEE · 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine · in 28 records
- PO4 · Phosphate ion · in 24 records
- JZR · hexyl beta-D-glucopyranoside · in 6 records
- 8PE · (2R)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(tetradecanoyloxy)propyl octadecanoate · in 5 records
- UNL · Unknown ligand · in 2 records
- UQ2 · Ubiquinone-2 · in 1 record
Experiment against prediction
- 2A06 chain F against the predicted model P00129: TM-score 0.98, RMSD 0.55 Å
- 2A06 chain F against the predicted model P00129: TM-score 0.98, RMSD 0.55 Å
- 1PPJ chain F against the predicted model P00129: TM-score 0.98, RMSD 0.57 Å
- 1PPJ chain F against the predicted model P00129: TM-score 0.98, RMSD 0.57 Å
- 1SQX chain F against the predicted model P00129: TM-score 0.97, RMSD 0.61 Å
- 1SQX chain F against the predicted model P00129: TM-score 0.97, RMSD 0.61 Å
- 1SQV chain F against the predicted model P00129: TM-score 0.97, RMSD 0.63 Å
- 1SQV chain F against the predicted model P00129: TM-score 0.97, RMSD 0.63 Å
- 1PP9 chain F against the predicted model P00129: TM-score 0.97, RMSD 0.62 Å
- 1PP9 chain F against the predicted model P00129: TM-score 0.97, RMSD 0.62 Å
Elsewhere
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