UniProt P13272
Cytochrome b-c1 complex subunit Rieske, mitochondrial (P13272)
Cytochrome b-c1 complex subunit Rieske, mitochondrial (UniProt P13272), EC 1.10.2.2, 7.1.1.8: 83 experimental structures and 1 predicted model on GenesisL1, 6 ligands bound, 140 pockets. Binding sites, druggability and experiment…
- UniProt
- P13272
- Protein
- Cytochrome b-c1 complex subunit Rieske, mitochondrial
- EC
- 1.10.2.2, 7.1.1.8
- Experimental structures
- 83
- Predicted models
- 1
- Ligands
- 6
- Pockets
- 140 · 16 records with a druggable one
Structures
84 records of P13272 in the MolNFT archive: 83 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1BCC | Cytochrome BC1 complex from chicken | x-ray diffraction | A, E | — | — |
| 1BCC | Cytochrome BC1 complex from chicken | x-ray diffraction | A, E | — | — |
| 1BE3 | Cytochrome BC1 complex from bovine | x-ray diffraction | E, I | — | — |
| 1BE3 | Cytochrome BC1 complex from bovine | x-ray diffraction | E, I | — | — |
| 1BGY | Cytochrome BC1 complex from bovine | x-ray diffraction | E, I, Q, U | — | — |
| 1BGY | Cytochrome BC1 complex from bovine | x-ray diffraction | E, I, Q, U | — | — |
| 1L0L | structure of bovine mitochondrial cytochrome bc1 complex with a bound fungicide famoxadone | x-ray diffraction | E, I | — | — |
| 1L0L | Structure of bovine mitochondrial cytochrome BC1 complex with a bound fungicide famoxadone | x-ray diffraction | E, I | — | — |
| 1L0N | native structure of bovine mitochondrial cytochrome bc1 complex | x-ray diffraction | E, I | — | — |
| 1L0N | Native structure of bovine mitochondrial cytochrome BC1 complex | x-ray diffraction | E, I | — | — |
| 1NTK | Crystal Structure of Mitochondrial Cytochrome bc1 in Complex with Antimycin A1 | x-ray diffraction | E, I | — | — |
| 1NTK | Crystal structure of mitochondrial cytochrome BC1 in complex with antimycin A1 | x-ray diffraction | E, I | — | — |
| 1NTM | Crystal Structure of Mitochondrial Cytochrome bc1 Complex at 2.4 Angstrom | x-ray diffraction | E, I | — | — |
| 1NTM | Crystal structure of mitochondrial cytochrome BC1 complex at 2.4 ångström | x-ray diffraction | E, I | — | — |
| 1NTZ | Crystal Structure of Mitochondrial Cytochrome bc1 Complex Bound with Ubiqui | x-ray diffraction | E, I | — | — |
| 1NTZ | Crystal structure of mitochondrial cytochrome BC1 complex bound with ubiquinone | x-ray diffraction | E, I | — | — |
| 1NU1 | Crystal Structure of Mitochondrial Cytochrome bc1 Complexed with 2-nonyl-4-hydroxyquinoline N-oxide… | x-ray diffraction | E, I | — | — |
| 1NU1 | Crystal structure of mitochondrial cytochrome BC1 complexed with 2- nonyl-4-hydroxyquinoline… | x-ray diffraction | E, I | — | — |
| 1PP9 | Bovine cytochrome bc1 complex with stigmatellin bound | x-ray diffraction | E, I, R, V | — | — |
| 1PP9 | Bovine cytochrome BC1 complex with stigmatellin bound | x-ray diffraction | E, I, R, V | — | — |
| 1PPJ | Bovine cytochrome bc1 complex with stigmatellin and antimycin | x-ray diffraction | E, I, R, V | — | — |
| 1PPJ | Bovine cytochrome BC1 complex with stigmatellin and antimycin | x-ray diffraction | E, I, R, V | — | — |
| 1QCR | Crystal structure of bovine mitochondrial cytochrome BC1 complex, alpha carbon atoms only | x-ray diffraction | E, I | — | — |
| 1QCR | Crystal structure of bovine mitochondrial cytochrome BC1 complex, alpha carbon atoms only | x-ray diffraction | E, I | — | — |
| 1RIE | Structure of a water soluble fragment of the rieske iron-sulfur protein of the bovine heart… | x-ray diffraction | A | — | — |
| 1RIE | Structure of a water soluble fragment of the rieske iron- sulfur protein of the bovine heart… | x-ray diffraction | A | — | — |
| 1SQB | Crystal Structure Analysis of Bovine Bc1 with Azoxystrobin | x-ray diffraction | E, I | — | — |
| 1SQB | Crystal structure analysis of bovine BC1 with azoxystrobin | x-ray diffraction | E, I | — | — |
| 1SQP | Crystal Structure Analysis of Bovine Bc1 with Myxothiazol | x-ray diffraction | E, I | — | — |
| 1SQP | Crystal structure analysis of bovine BC1 with myxothiazol | x-ray diffraction | E, I | — | — |
| 1SQQ | Crystal Structure Analysis of Bovine Bc1 with Methoxy Acrylate Stilbene (MOAS) | x-ray diffraction | E, I | — | — |
| 1SQQ | Crystal structure analysis of bovine BC1 with methoxy acrylate stilbene (moas) | x-ray diffraction | E, I | — | — |
| 1SQV | Crystal Structure Analysis of Bovine Bc1 with UHDBT | x-ray diffraction | E, I | — | — |
| 1SQV | Crystal structure analysis of bovine BC1 with uhdbt | x-ray diffraction | E, I | — | — |
| 1SQX | Crystal Structure Analysis of Bovine Bc1 with Stigmatellin A | x-ray diffraction | E, I | — | — |
| 1SQX | Crystal structure analysis of bovine BC1 with stigmatellin a | x-ray diffraction | E, I | — | — |
| 2A06 | Bovine cytochrome bc1 complex with stigmatellin bound | x-ray diffraction | E, I, R, V | — | — |
| 2A06 | Bovine cytochrome BC1 complex with stigmatellin bound | x-ray diffraction | E, I, R, V | — | — |
| 2FYU | Crystal structure of bovine heart mitochondrial bc1 with jg144 inhibitor | x-ray diffraction | E, I | — | — |
| 2FYU | Crystal structure of bovine heart mitochondrial BC1 with JG144 inhibitor | x-ray diffraction | E, I | — | — |
| 2YBB | Fitted model for bovine mitochondrial supercomplex I1III2IV1 by single particle cryo-EM (EMD-1876) | electron microscopy | E, I, e, i | — | — |
| 2YBB | Fitted model for bovine mitochondrial supercomplex I1III2IV1 by single particle cryo-EM (emd-1876) | electron microscopy | E, I, e, i | — | — |
| 3BCC | Stigmatellin and antimycin bound cytochrome BC1 complex from chicken | x-ray diffraction | E | — | — |
| 3BCC | Stigmatellin and antimycin bound cytochrome BC1 complex from chicken | x-ray diffraction | E | — | — |
| 4D6T | Cytochrome bc1 bound to the 4(1H)-pyridone GW844520 | x-ray diffraction | E, I, R, V | — | — |
| 4D6T | Cytochrome BC1 bound to the 4(1H)-pyridone GW844520 | x-ray diffraction | E, I, R, V | — | — |
| 4D6U | Cytochrome bc1 bound to the 4(1H)-pyridone GSK932121 | x-ray diffraction | E, I, R, V | — | — |
| 4D6U | Cytochrome BC1 bound to the 4(1H)-pyridone GSK932121 | x-ray diffraction | E, I, R, V | — | — |
| 5GPN | Architecture of mammalian respirasome | electron microscopy | I, U | — | 3 (best 0.85) |
| 5KLV | Structure of bos taurus cytochrome bc1 with fenamidone inhibited | x-ray diffraction | E, I | FES | — |
| 5KLV | Structure of bos taurus cytochrome BC1 with fenamidone inhibited | x-ray diffraction | E, I | FES | — |
| 5LUF | Cryo-EM of bovine respirasome | electron microscopy | e, i, q, u | FES | — |
| 5LUF | Cryo-EM of bovine respirasome | electron microscopy | e, i, q, u | FES | — |
| 5NMI | Cytochrome bc1 bound to the inhibitor MJM170 | x-ray diffraction | E, I, R, V | PEE, FES | — |
| 5NMI | Cytochrome BC1 bound to the inhibitor MJM170 | x-ray diffraction | E, I, R, V | PEE, FES | — |
| 5OKD | Crystal structure of bovine cytochrome BC1 in complex with inhibitor SCR0911. | x-ray diffraction | E, I | FES, PX4, PO4, PEE, CDL | — |
| 6FO0 | CryoEM structure of bovine cytochrome bc1 in complex with the anti-malarial compound GSK932121 | electron microscopy | R, E | — | 9 (best 0.82) |
| 6FO0 | Cryoem structure of bovine cytochrome BC1 in complex with the anti- malarial compound GSK932121 | electron microscopy | R, E | — | — |
| 6FO2 | CryoEM structure of bovine cytochrome bc1 with no ligand bound | electron microscopy | R, V, E, I | — | 10 (best 0.83) |
| 6FO2 | Cryoem structure of bovine cytochrome BC1 with no ligand bound | electron microscopy | R, V, E, I | — | — |
24 records more on the page itself.
Ligands
- FES · Fe2/s2 (inorganic) cluster · in 25 records
- PEE · 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine · in 15 records
- PX4 · 1,2-dimyristoyl-sn-glycero-3-phosphocholine · in 13 records
- CDL · Cardiolipin · in 11 records
- PO4 · Phosphate ion · in 9 records
- JHB · 7-chloranyl-3-methyl-2-[4-[[4-(trifluoromethyloxy) phenyl]methyl]phenyl]-1~{H}-quinolin-4-one · in 1 record
Experiment against prediction
- 1RIE chain A against the predicted model P13272: TM-score 0.99, RMSD 0.52 Å
- 5NMI chain R against the predicted model P13272: TM-score 0.97, RMSD 0.55 Å
- 6NHG chain E against the predicted model P13272: TM-score 0.97, RMSD 0.92 Å
- 4D6U chain E against the predicted model P13272: TM-score 0.97, RMSD 0.60 Å
- 4D6T chain E against the predicted model P13272: TM-score 0.96, RMSD 0.63 Å
- 6FO6 chain E against the predicted model P13272: TM-score 0.96, RMSD 1.02 Å
- 4D6U chain R against the predicted model P13272: TM-score 0.95, RMSD 1.10 Å
- 5NMI chain E against the predicted model P13272: TM-score 0.95, RMSD 1.18 Å
- 1SQP chain E against the predicted model P13272: TM-score 0.95, RMSD 1.25 Å
- 1SQQ chain E against the predicted model P13272: TM-score 0.95, RMSD 1.25 Å
Elsewhere
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