UniProt O75044
SLIT-ROBO Rho GTPase-activating protein 2 (O75044)
SLIT-ROBO Rho GTPase-activating protein 2 (UniProt O75044): 12 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 25 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- O75044
- Protein
- SLIT-ROBO Rho GTPase-activating protein 2
- Experimental structures
- 12
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 25 · 2 records with a druggable one
Structures
13 records of O75044 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2DL8 | Solution structure of the SH3 domain of human SLIT-ROBO Rho GTPase-activating protein 2 | solution nmr | A | — | — |
| 2DL8 | Solution structure of the SH3 domain of human slit-robo rho GTPase- activating protein 2 | solution nmr | A | — | — |
| 4RTT | Cyrstal structure of SLIT-ROBO Rho GTPase-activating protein 2 fragment | x-ray diffraction | A, B | SO4 | 2 (best 0.30) |
| 4RTT | Cyrstal structure of slit-robo rho GTPase-activating protein 2 fragment | x-ray diffraction | A, B | SO4 | 2 (best 0.30) |
| 4RUG | Cyrstal structure of SLIT-ROBO Rho GTPase-activating protein 2 fragment | x-ray diffraction | A, B | — | 1 (best 0.28) |
| 4RUG | Cyrstal structure of slit-robo rho GTPase-activating protein 2 fragment | x-ray diffraction | A, B | — | 1 (best 0.28) |
| 5I6J | Crystal Structure of SRGAP2 F-BARx | x-ray diffraction | A | — | 2 (best 0.51) |
| 5I6J | Crystal structure of SRGAP2 F-barx | x-ray diffraction | A | — | 2 (best 0.51) |
| 5I6R | Crystal Structure of srGAP2 F-BARx WT Form-1 | x-ray diffraction | A | MLT | — |
| 5I6R | Crystal structure of SRGAP2 F-barx wt form-1 | x-ray diffraction | A | MLT | — |
| 5I7D | Crystal Structure of srGAP2 F-BARx WT Form-2 | x-ray diffraction | A, B | — | 4 (best 0.38) |
| 5I7D | Crystal structure of SRGAP2 F-barx wt form-2 | x-ray diffraction | A, B | — | 4 (best 0.38) |
| O75044 | AlphaFold monomer V2.0 prediction for slit-robo rho GTPase-activating protein 2 (O75044) | predicted | A | — | 7 (best 0.50) |
Ligands
Experiment against prediction
- 5I6R chain A against the predicted model O75044: TM-score 0.98, RMSD 1.22 Å
- 5I6R chain A against the predicted model O75044: TM-score 0.98, RMSD 1.22 Å
- 5I6J chain A against the predicted model O75044: TM-score 0.97, RMSD 1.44 Å
- 5I6J chain A against the predicted model O75044: TM-score 0.97, RMSD 1.44 Å
- 5I7D chain A against the predicted model O75044: TM-score 0.92, RMSD 2.21 Å
- 5I7D chain A against the predicted model O75044: TM-score 0.92, RMSD 2.21 Å
- 2DL8 chain A against the predicted model O75044: TM-score 0.80, RMSD 2.19 Å
- 2DL8 chain A against the predicted model O75044: TM-score 0.80, RMSD 2.19 Å
- 4RTT chain B against the predicted model O75044: TM-score 0.72, RMSD 1.12 Å
- 4RTT chain B against the predicted model O75044: TM-score 0.72, RMSD 1.12 Å
Elsewhere
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