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Ligand · MLT

MLT · D-malate

MLT, D-malate (C4 H6 O5, 134.1 g/mol), in the MolNFT structures on GenesisL1: bound in 117 records (79 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with it.

Component
MLT
Formula
C4 H6 O5
Class
ligand
Structures
117
PDB entries
79

Binding sites

MLT in 117 structures; the first of them:

  • 5A2R · A New Crystal Structure of the Drosophila melanogaster Angiotensin Converting Enzyme… · MLT A1615 · binds GLN265, HIS337, ALA338, HIS367, GLU368, PHE441, LYS495, HIS497 and 2 more
  • 5BV1 · Crystal Structure of a Vps33-Vps16 Complex from Chaetomium thermophilum · MLT B901 · binds ASP617, ARG618, ARG619, LEU620, ASN653, HIS657
  • 5CUV · Crystal structure of Trypanosoma cruzi Vacuolar Soluble Pyrophosphatases in apo form · MLT A501 · binds ARG213, LYS215, LEU219, PRO220, MSE221, ASN222, ARG223, LYS314 and 1 more
  • 5E5U · Crystal structure of the complex between Carbonic anhydrase-like domain of PTPRG and… · MLT B403 · binds LYS222, ARG303
  • 5EQV · 1.45 Angstrom Crystal Structure of Bifunctional 2',3'-cyclic Nucleotide… · MLT A406 · binds ASN124, HIS125, TRP195, GLU246, HIS265
  • 5HZO · GFP mutant S205G · MLT A301 · binds PRO58, VAL61, ASN144, TYR145, ASN146, HIS148, ILE167, ARG168 and 1 more
  • 5I5A · quasi racemic structure of allo-Ile7-ShK and D-ShK · MLT B101 · binds DAR11, DTH13, DPN15, DGN16, DTY23
  • 5I6R · Crystal Structure of srGAP2 F-BARx WT Form-1 · MLT A501 · binds MET61, SER64, ARG65, GLU68, SER110, ARG111, THR114
  • 5IKM · 1.9 Angstrom Crystal Structure of NS5 Methyl Transferase from Dengue Virus 1 in Complex… · MLT A313 · binds LYS105, ASP131, PHE133, PHE134, ARG163
  • 5IQX · 1.05A resolution structure of Holo HasAp (R33A) from Pseudomonas aeruginosa · MLT A202 · binds ASN47, GLN55, GLY105, GLY106, TYR107
  • 5L8X · X-ray structure of apo methanocaldococcus jannaschii methyltransferase subunit a at 1.85… · MLT B201 · binds CYS52, HIS53, THR54, GLY58, LYS61
  • 5MFN · Designed armadillo repeat protein YIIIM5AII · MLT A302 · binds LEU146, SER147, PRO182, ALA183, GLN186, LEU187
  • 5N4M · Human myelin protein P2, mutant I43N · MLT A203 · binds LYS10, ALA37, LYS38, SER56, THR57
  • 5N4P · Human myelin P2, mutant I52T · MLT A202 · binds LYS10, ALA37, LYS38, PRO39, SER56, THR57
  • 5N4Q · Human myelin protein P2, mutant T51P · MLT A203 · binds LYS10, ALA37, LYS38, SER56, THR57
  • 5TK2 · Crystal Structure of Uncharacterized Cupredoxin-like domain protein from Bacillus… · MLT A202 · binds GLY94, LYS95, GLU96
  • 5U8Q · Structure of the ectodomain of the human Type 1 insulin-like growth factor receptor in… · MLT A1003 · binds TYR226, ARG245, CYS246, VAL247, ASP248, PHE251, ASP31
  • 5U9C · 1.9 Angstrom Resolution Crystal Structure of dTDP-4-dehydrorhamnose Reductase from… · MLT B301 · binds VAL66, LYS164, PHE165, LYS168, ARG222, ARG253
  • 5V32 · Ethylene forming enzyme in complex with manganese and malic acid · MLT A402 · binds ARG171, LEU173, PHE175, ILE186, HIS189, ASP191, LEU206, HIS268 and 4 more
  • 5VKT · Cinnamyl alcohol dehydrogenases (SbCAD4) from Sorghum bicolor (L.) Moench · MLT A406 · binds SER99, ARG101, CYS106, GLU111, ASP146, PHE147, VAL305
  • 5WE7 · Crystal structure of the influenza virus PA endonuclease in complex with an inhibitor… · MLT A304 · binds SER49, LYS73, PHE76, GLU77, ILE78, TYR112
  • 5XBF · Crystal Structure of Myo7b C-terminal MyTH4-FERM in complex with USH1C PDZ3 · MLT A2203 · binds SER2055, SER2056, TRP2057, ASP2088, THR2092
  • 6BPY · Aspergillus fumigatus Thioredoxin Reductase · MLT B410 · binds GLY280, THR305, GLY308, SER309, ILE312, GLY280, THR305, GLY308 and 2 more
  • 6CTY · Crystal structure of dihydroorotase pyrC from Yersinia pestis in complex with zinc and… · MLT A403 · binds HIS17, HIS19, ARG21, ASN45, KCX103, THR110, THR111, HIS140 and 7 more
  • 6DZG · Crystal structure of polyphosphate kinase 2 class I (SMc02148) in complex with ADP · MLT A402 · binds ALA94, ALA95, GLY96, LYS97, GLY98, GLY99, ASP148, ARG209 and 1 more

Residues it binds most

ARG 128, HIS 97, GLY 94, ALA 75, LYS 83, THR 81, SER 73, LEU 58, ASN 74, TYR 59 (residue and the binding sites it lines).

Found with

  • EDO · 1,2-ethanediol
  • ZN · Zinc ion
  • GOL · Glycerol
  • ACT · Acetate ion
  • NA · Sodium ion
  • LMR · (2S)-2-hydroxybutanedioic acid
  • SO4 · Sulfate ion
  • FMT · Formic acid
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose
  • CL · Chloride ion
  • MLA · Malonic acid
  • PG4 · Tetraethylene glycol

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