UniProt O14791
Apolipoprotein L1 (O14791)
Apolipoprotein L1 (UniProt O14791): 8 experimental structures and 1 predicted model on GenesisL1, 4 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O14791
- Protein
- Apolipoprotein L1
- Experimental structures
- 8
- Predicted models
- 1
- Pockets
- 4 · 1 record with a druggable one
Structures
9 records of O14791 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7L6K | APOL1 N-terminal domain | solution nmr | A | — | — |
| 7LF7 | Fab 6D12 bound to ApoL1 NTD | x-ray diffraction | K, M | — | 4 (best 0.72) |
| 7LF7 | Fab 6D12 bound to APOL1 ntd | x-ray diffraction | K, M | — | — |
| 7LFA | Fab 3B6 bound to ApoL1 NTD | x-ray diffraction | A, C | — | — |
| 7LFA | Fab 3B6 bound to APOL1 ntd | x-ray diffraction | A, C | — | — |
| 7LFB | Fab 7D6 bound to ApoL1 NTD | x-ray diffraction | X | — | — |
| 7LFB | Fab 7D6 bound to APOL1 ntd | x-ray diffraction | X | — | — |
| 7LFD | Fab 7D6 bound to APOL1 BH3 like peptide | x-ray diffraction | A | — | — |
| O14791 | AlphaFold monomer V2.0 prediction for apolipoprotein L1 (O14791) | predicted | A | — | — |
Experiment against prediction
- 7LF7 chain K against the predicted model O14791: TM-score 0.80, RMSD 1.88 Å
- 7LF7 chain K against the predicted model O14791: TM-score 0.80, RMSD 1.88 Å
- 7LF7 chain M against the predicted model O14791: TM-score 0.79, RMSD 1.87 Å
- 7LF7 chain M against the predicted model O14791: TM-score 0.79, RMSD 1.87 Å
- 7LFA chain A against the predicted model O14791: TM-score 0.74, RMSD 2.87 Å
- 7LFA chain A against the predicted model O14791: TM-score 0.74, RMSD 2.87 Å
- 7L6K chain A against the predicted model O14791: TM-score 0.68, RMSD 3.04 Å
- 7LFD chain A against the predicted model O14791: TM-score 0.65, RMSD 0.65 Å
- 7LFA chain C against the predicted model O14791: TM-score 0.63, RMSD 3.12 Å
- 7LFA chain C against the predicted model O14791: TM-score 0.63, RMSD 3.12 Å
Elsewhere
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