MolNFT v2 · #185662 · protein

Fab 3B6 bound to ApoL1 NTD

7LFA: “Fab 3B6 bound to ApoL1 NTD”. X-ray diffraction at 1.857, 1 ligand (CL). MolNFT v2 #185662 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7LFA
Type: protein
Length: 1,058 residues
Chains: 6
Method: x-ray diffraction
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: 1.857
Source: Homo sapiens
UniProt: O14791
Ligands: CL

Structure

x-ray diffraction · resolution 1.857 · 4 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	94	—	O14791
B, H	—	protein	220	—	—
C	—	protein	100	—	O14791
D, L	—	protein	212	—	—

Ligands and binding sites

CL · Chloride ion · ion · 2 copies · chains D, L
GOL · Glycerol · additive · 2 copies · chains B, H, L

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

7LFA · Fab 3B6 bound to APOL1 ntd · the same entry in another collection · chain L against L, TM-score 1.00
O14791 · AlphaFold monomer V2.0 prediction for apolipoprotein L1 (O14791) · a predicted model of the same protein · chain A against A, TM-score 0.74

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O14791
Elsewhere: RCSB PDB 7LFA · PDBe 7LFA · UniProt O14791

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