MolNFT v2 · #185663 · protein

Fab 7D6 bound to ApoL1 NTD

7LFB: “Fab 7D6 bound to ApoL1 NTD”. X-ray diffraction at 1.913, 1 ligand (SO4). MolNFT v2 #185663 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7LFB
Type: protein
Length: 518 residues
Chains: 3
Method: x-ray diffraction
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: 1.913
Source: Homo sapiens
UniProt: O14791
Ligands: SO4

Structure

x-ray diffraction · resolution 1.913 · 3 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
H	—	protein	224	—	—
L	—	protein	214	—	—
X	—	protein	80	—	O14791

Ligands and binding sites

SO4 · Sulfate ion · ion · 2 copies · chains L
GOL · Glycerol · additive · 2 copies · chains H, L
MES · 2-(N-morpholino)-ethanesulfonic acid · additive · chains H, L

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

7LFB · Fab 7D6 bound to APOL1 ntd · the same entry in another collection · chain H against H, TM-score 1.00
O14791 · AlphaFold monomer V2.0 prediction for apolipoprotein L1 (O14791) · a predicted model of the same protein · chain X against A, TM-score 0.48

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O14791
Elsewhere: RCSB PDB 7LFB · PDBe 7LFB · UniProt O14791

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