UniProt O00214
Isoform 2 of Galectin-8 (O00214)
Isoform 2 of Galectin-8 (UniProt O00214): 55 experimental structures on GenesisL1, 12 ligands bound, 1 pocket. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- O00214
- Protein
- Isoform 2 of Galectin-8
- Experimental structures
- 55
- Predicted models
- 0
- Ligands
- 12
- Pockets
- 1 · 0 records with a druggable one
Structures
55 records of O00214 in the MolNFT archive: 55 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2YRO | Solution structure of the C-terminal Gal-bind lectin protein from Human Galectin-8 | solution nmr | A | — | — |
| 2YRO | Solution structure of the C-terminal gal-bind lectin protein from human galectin-8 | solution nmr | A | — | — |
| 3AP4 | Crystal structure of the galectin-8 N-terminal carbohydrate recognition domain in complex with… | x-ray diffraction | A, B, C, D | — | — |
| 3AP4 | Crystal structure of the galectin-8 N-terminal carbohydrate recognition domain in complex with… | x-ray diffraction | A, B, C, D | — | — |
| 3AP5 | Crystal structure of the galectin-8 N-terminal carbohydrate recognition domain | x-ray diffraction | A | — | — |
| 3AP5 | Crystal structure of the galectin-8 N-terminal carbohydrate recognition domain | x-ray diffraction | A | — | — |
| 3AP6 | Crystal structure of the galectin-8 N-terminal carbohydrate recognition domain in complex with… | x-ray diffraction | A, B, C, D | — | — |
| 3AP6 | Crystal structure of the galectin-8 N-terminal carbohydrate recognition domain in complex with… | x-ray diffraction | A, B, C, D | — | — |
| 3AP7 | Crystal structure of the galectin-8 N-terminal carbohydrate recognition domain in complex with… | x-ray diffraction | A | — | — |
| 3AP7 | Crystal structure of the galectin-8 N-terminal carbohydrate recognition domain in complex with… | x-ray diffraction | A | — | — |
| 3AP9 | Crystal structure of the galectin-8 N-terminal carbohydrate recognition domain in complex with… | x-ray diffraction | A | — | — |
| 3AP9 | Crystal structure of the galectin-8 N-terminal carbohydrate recognition domain in complex with… | x-ray diffraction | A | — | — |
| 3APB | Crystal structure of the galectin-8 N-terminal carbohydrate recognition domain in complex with… | x-ray diffraction | A, B | — | — |
| 3APB | Crystal structure of the galectin-8 N-terminal carbohydrate recognition domain in complex with… | x-ray diffraction | A, B | — | — |
| 3OJB | Crystal structure of C-terminal domain of human galectin-8 | x-ray diffraction | A, B, C, D | — | — |
| 3OJB | Crystal structure of C-terminal domain of human galectin-8 | x-ray diffraction | A, B, C, D | — | — |
| 3VKL | Protease-resistant mutant form of human Galectin-8 in complex with two lactose molecules | x-ray diffraction | A, B | — | — |
| 3VKL | Protease-resistant mutant form of human galectin-8 in complex with two lactose molecules | x-ray diffraction | A, B | — | — |
| 3VKM | Protease-resistant mutant form of Human Galectin-8 in complex with sialyllactose and lactose | x-ray diffraction | A, B | — | — |
| 3VKM | Protease-resistant mutant form of human galectin-8 in complex with sialyllactose and lactose | x-ray diffraction | A, B | — | — |
| 3VKN | Galectin-8 N-terminal domain in free form | x-ray diffraction | A, B | — | — |
| 3VKN | Galectin-8 N-terminal domain in free form | x-ray diffraction | A, B | — | — |
| 3VKO | Galectin-8 N-terminal domain in complex with sialyllactosamine | x-ray diffraction | A, B | — | — |
| 3VKO | Galectin-8 N-terminal domain in complex with sialyllactosamine | x-ray diffraction | A, B | — | — |
| 4BMB | Crystal structure of the N terminal domain of human Galectin 8 | x-ray diffraction | A | — | — |
| 4BMB | Crystal structure of the N terminal domain of human galectin 8 | x-ray diffraction | A | — | — |
| 4BME | Crystal structure of the N terminal domain of human Galectin 8, F19Y mutant | x-ray diffraction | A, B | — | — |
| 4BME | Crystal structure of the N terminal domain of human galectin 8, F19Y mutant | x-ray diffraction | A, B | — | — |
| 4FQZ | Crystal structure of a protease-resistant mutant form of human galectin-8 | x-ray diffraction | A | — | — |
| 4FQZ | Crystal structure of a protease-resistant mutant form of human galectin-8 | x-ray diffraction | A | — | — |
| 4GXL | The crystal structure of Galectin-8 C-CRD in complex with NDP52 | x-ray diffraction | A | — | — |
| 4GXL | The crystal structure of galectin-8 C-crd in complex with NDP52 | x-ray diffraction | A | — | — |
| 4HAN | Crystal structure of Galectin 8 with NDP52 peptide | x-ray diffraction | A, B | — | — |
| 4HAN | Crystal structure of galectin 8 with NDP52 peptide | x-ray diffraction | A, B | — | — |
| 5GZC | Crystal structure of Galectin-8 N-CRD with part of linker | x-ray diffraction | A | NA | — |
| 5GZC | Crystal structure of galectin-8 N-crd with part of linker | x-ray diffraction | A | — | — |
| 5GZD | Galectin-8 N-terminal domain carbohydrate recognition domain | x-ray diffraction | A | BGC, GAL | — |
| 5GZD | Galectin-8 N-terminal domain carbohydrate recognition domain | x-ray diffraction | A | — | — |
| 5GZE | Galectin-8 N-terminal domain carbohydrate recognition domain | x-ray diffraction | A | BGC, GAL | — |
| 5GZE | Galectin-8 N-terminal domain carbohydrate recognition domain | x-ray diffraction | A | — | — |
| 5GZF | Galectin-8 N-terminal domain carbohydrate recognition domain | x-ray diffraction | A | — | — |
| 5GZG | Galectin-8 N-terminal domain carbohydrate recognition domain | x-ray diffraction | A | — | — |
| 5T7I | Crystal structure of galectin-8N in complex with lnnt | x-ray diffraction | A | BGC, GAL, NAG | — |
| 5T7S | Crystal structure of galectin-8N in complex with lactose | x-ray diffraction | A | GLC, GAL | — |
| 5T7T | Galectin-8 N terminal domain in complex with lnt | x-ray diffraction | A | NAG, GAL, CL | — |
| 5T7U | Crystal structure of galectin-8N in complex with glycerol | x-ray diffraction | A | NA, CL | — |
| 5VWG | Galectin-8 N terminal domain in complex with methyl 3-O-[1- carboxyethyl]-beta-D-galactopyranoside | x-ray diffraction | A | 9QG | — |
| 6W4Z | Galectin-8N terminal domain in complex with methyl 3-O-[3-O… | x-ray diffraction | A, B | SZS, CL | — |
| 6Z6Y | Galectin-8 N-terminal domain in complex with a sulfatide mimicking a sphingolipid | x-ray diffraction | A | L4L | — |
| 7AEN | Galectin-8 N-terminal carbohydrate recognition domain in complex with methyl… | x-ray diffraction | A, B | R8B, CL | 1 (best 0.47) |
| 7AEN | Galectin-8 N-terminal carbohydrate recognition domain in complex with methyl… | x-ray diffraction | A, B | R8B, CL | — |
| 7ALS | Alpha and beta lactose isomer structure of galectin 8, N-terminal domain | x-ray diffraction | A, B | BGC, GAL, GLC, CL | — |
| 7P11 | Galectin-8 N-terminal carbohydrate recognition domain in complex with quinoline D-galactal ligand | x-ray diffraction | A, B | 5KM, CL | — |
| 7P1M | Galectin-8 N-terminal carbohydrate recognition domain in complex with benzimidazole D-galactal… | x-ray diffraction | A, B | 4IU, CL | — |
| O00214 | AlphaFold monomer V2.0 prediction for galectin-8 (O00214) | — | — | — |
Ligands
- CL · Chloride ion · in 8 records
- GAL · beta-D-galactopyranose · in 6 records
- BGC · beta-D-glucopyranose · in 4 records
- GLC · alpha-D-glucopyranose · in 2 records
- NA · Sodium ion · in 2 records
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 2 records
- R8B · methyl 3-O-((7-carboxy) quinolin-2-yl)-methyl)-beta-D-galactopyranoside · in 2 records
- 4IU · 2-[[(2R,3R,4R)-2-(hydroxymethyl)-3-oxidanyl-3,4-dihydro-2H-pyran-4-yl]oxymethyl]-3-methyl-benzimidazole-5-carboxylic acid · in 1 record
- 5KM · 2-[[(2~{R},3~{R},4~{R})-2-(hydroxymethyl)-3-oxidanyl-3, 4-dihydro-2~{H}-pyran-4-yl]oxymethyl]quinoline-7-carboxylic acid · in 1 record
- 9QG · Methyl 3-O-[(1R)-1-carboxyethyl]-beta-D-galactopyranoside · in 1 record
- L4L · [(2~{R},3~{R},4~{S},5~{S},6~{R})-2-[(2~{S})-2-acetamido-3-oxidanylidene-pent-4-enoxy]-6-(hydroxymethyl)-3,5-bis(oxidanyl)oxan-4-yl] hydrogen sulfate · in 1 record
- SZS · Methyl 3-O-[3-(benzyloxy)-3-oxopropanoyl]-beta-D-galactopyranoside · in 1 record
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.