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UniProt H6QM90

Polymerase basic protein 2 (H6QM90)

Polymerase basic protein 2 (UniProt H6QM90): 31 experimental structures on GenesisL1, 4 ligands bound, 161 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
H6QM90
Protein
Polymerase basic protein 2
Experimental structures
31
Predicted models
0
Ligands
4
Pockets
161 · 14 records with a druggable one

Structures

31 records of H6QM90 in the MolNFT archive: 31 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
4WSBBat influenza a polymerase with bound vrna promoterx-ray diffractionC——
5M3HBat influenza A/H17N10 polymerase bound to four heptad repeats of serine 5 phosphorylated Pol II CTDx-ray diffractionCPO4—
5M3HBat influenza A/H17N10 polymerase bound to four heptad repeats of serine 5 phosphorylated pol II ctdx-ray diffractionCPO4—
6EVJCrystal structure of bat influenza A/H17N10 polymerase with viral RNA promoter and capped RNA primerx-ray diffractionC, F—15 (best 0.89)
6EVJCrystal structure of bat influenza A/H17N10 polymerase with viral RNA promoter and capped RNA primerx-ray diffractionC, F——
6EVKCrystal structure of bat influenza A/H17N10 polymerase with viral RNA promoter and cap analogue…x-ray diffractionCPO4, MGP13 (best 0.84)
6EVKCrystal structure of bat influenza A/H17N10 polymerase with viral RNA promoter and cap analogue…x-ray diffractionCPO4, MGP—
6FHHCrystal structure of bat influenza A/H17N10 polymerase with viral RNA promoter bound to a 22-mer…x-ray diffractionCPO411 (best 0.88)
6FHHCrystal structure of bat influenza A/H17N10 polymerase with viral RNA promoter bound to a 22-mer…x-ray diffractionCPO4—
6FHICrystal structure of bat influenza A/H17N10 polymerase with viral RNA promoter bound to a 19-mer…x-ray diffractionCPO414 (best 0.87)
6FHICrystal structure of bat influenza A/H17N10 polymerase with viral RNA promoter bound to a 19-mer…x-ray diffractionCPO4—
6SZUBat Influenza A polymerase pre-termination complex with pyrophosphate using 44-mer vRNA template…electron microscopyC—9 (best 0.90)
6SZUBat influenza a polymerase pre-termination complex with pyrophosphate using 44-mer vrna template…electron microscopyC——
6SZVBat Influenza A polymerase elongation complex with incoming UTP analogue (core + endonuclease only)electron microscopyC—11 (best 0.90)
6SZVBat influenza a polymerase elongation complex with incoming UTP analogue (core + endonuclease only)electron microscopyC——
6T0NBat Influenza A polymerase pre-initiation complexelectron microscopyC—11 (best 0.86)
6T0NBat influenza a polymerase pre-initiation complexelectron microscopyC——
6T0RBat Influenza A polymerase product dissociation complex using 44-mer vRNA template with mutated…electron microscopyC—11 (best 0.80)
6T0RBat influenza a polymerase product dissociation complex using 44-mer vrna template with mutated…electron microscopyC——
6T0SBat Influenza A polymerase stuttering complex using 44-mer vRNA template with intact oligo(U)…electron microscopyC—10 (best 0.87)
6T0SBat influenza a polymerase stuttering complex using 44-mer vrna template with intact OLIGO(U)…electron microscopyC——
6T0UBat Influenza A polymerase product dissociation complex using 44-mer vRNA template with intact…electron microscopyC—10 (best 0.86)
6T0UBat influenza a polymerase product dissociation complex using 44-mer vrna template with intact…electron microscopyC——
6T0VBat Influenza A polymerase elongation complex with incoming UTP analogue (complete polymerase)electron microscopyC——
6T0VBat influenza a polymerase elongation complex with incoming UTP analogue (complete polymerase)electron microscopyCGTG—
6T2CBat Influenza A polymerase recycling complexelectron microscopyC—5 (best 0.64)
6T2CBat influenza a polymerase recycling complexelectron microscopyC——
6TW1Bat Influenza A polymerase termination complex with pyrophosphate using 44-mer vRNA template with…electron microscopyC—13 (best 0.88)
6TW1Bat influenza a polymerase termination complex with pyrophosphate using 44-mer vrna template with…electron microscopyC——
9F2RInfluenza A/H17N10 polymerase with bound promoter and 3' end of template in active sitex-ray diffractionCMGT13 (best 0.88)
9F37Replication-like initiation state of influenza polymerase with GTP and CTP at respectively the -1…x-ray diffractionCMGT15 (best 0.89)

Ligands

  • PO4 · Phosphate ion · in 8 records
  • MGP · 7-methyl-guanosine-5'-triphosphate · in 2 records
  • MGT · 7N-methyl-8-hydroguanosine-5'-triphosphate · in 2 records
  • GTG · 7-methyl-guanosine-5'-triphosphate-5'-guanosine · in 1 record

Elsewhere

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