UniProt G0SAK3
Nucleoporin NUP145 (G0SAK3)
Nucleoporin NUP145 (UniProt G0SAK3), EC 3.4.21.-: 12 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 15 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- G0SAK3
- Protein
- Nucleoporin NUP145
- EC
- 3.4.21.-
- Experimental structures
- 12
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 15 · 3 records with a druggable one
Structures
13 records of G0SAK3 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5CWW | Crystal structure of the Chaetomium thermophilum heterotrimeric Nup82 NTD-Nup159 TAIL-Nup145N APD… | x-ray diffraction | A | — | 4 (best 0.76) |
| 5CWW | Crystal structure of the chaetomium thermophilum heterotrimeric NUP82 ntd-NUP159 tail-NUP145N apd… | x-ray diffraction | A | — | — |
| 5HB0 | Crystal structure of Chaetomium thermophilum Nup170 CTD-Nup145N complex | x-ray diffraction | E, F, G, H | — | — |
| 5HB0 | Crystal structure of chaetomium thermophilum NUP170 ctd-NUP145N complex | x-ray diffraction | E, F, G, H | — | — |
| 5HB5 | Crystal structure of Chaetomium thermophilum Nup145N APD | x-ray diffraction | A, B | — | 2 (best 0.32) |
| 5HB5 | Crystal structure of chaetomium thermophilum NUP145N apd | x-ray diffraction | A, B | — | — |
| 5HB6 | Crystal structure of Chaetomium thermophilum Nup145N APD T994A mutant fused to Nup145C N | x-ray diffraction | A, B | SO4 | — |
| 5HB6 | Crystal structure of chaetomium thermophilum NUP145N apd T994A mutant fused to NUP145C N | x-ray diffraction | A, B | — | — |
| 7MVV | Single particle cryo-EM structure of the Chaetomium thermophilum Nup192-Nic96-Nup53-Nup145N complex… | electron microscopy | C | — | — |
| 7MVV | Single particle cryo-EM structure of the chaetomium thermophilum NUP192-NIC96-NUP53-NUP145N complex… | electron microscopy | C | — | — |
| 7MVZ | Single particle cryo-EM structure of the Chaetomium thermophilum Nup188-Nic96-Nup145N complex… | electron microscopy | C | — | 1 (best 0.52) |
| 7MVZ | Single particle cryo-EM structure of the chaetomium thermophilum NUP188-NIC96-NUP145N complex… | electron microscopy | C | — | — |
| G0SAK3 | AlphaFold monomer V2.0 prediction for nucleoporin NUP145 (G0SAK3) | predicted | A | — | 8 (best 0.73) |
Ligands
- SO4 · Sulfate ion · in 1 record
Experiment against prediction
- 5HB5 chain B against the predicted model G0SAK3: TM-score 0.98, RMSD 0.72 Å
- 5HB5 chain B against the predicted model G0SAK3: TM-score 0.98, RMSD 0.72 Å
- 5HB5 chain A against the predicted model G0SAK3: TM-score 0.98, RMSD 0.75 Å
- 5HB5 chain A against the predicted model G0SAK3: TM-score 0.98, RMSD 0.75 Å
- 5CWW chain A against the predicted model G0SAK3: TM-score 0.97, RMSD 0.84 Å
- 5CWW chain A against the predicted model G0SAK3: TM-score 0.97, RMSD 0.84 Å
- 5HB6 chain A against the predicted model G0SAK3: TM-score 0.95, RMSD 1.03 Å
- 5HB6 chain A against the predicted model G0SAK3: TM-score 0.95, RMSD 1.03 Å
- 5HB6 chain B against the predicted model G0SAK3: TM-score 0.94, RMSD 1.39 Å
- 5HB6 chain B against the predicted model G0SAK3: TM-score 0.94, RMSD 1.39 Å
Elsewhere
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