UniProt F8WJP6
Gdp-mannose 4,6-dehydratase / gdp-4-amino-4,6-dideoxy-d-mannose formyltransferase (F8WJP6)
Gdp-mannose 4,6-dehydratase / gdp-4-amino-4,6-dideoxy-d-mannose formyltransferase (UniProt F8WJP6), EC 2.1.2.-, 4.2.1.47: 8 experimental structures on GenesisL1, 8 ligands bound, 28 pockets. Binding sites, pockets, druggability…
- UniProt
- F8WJP6
- Protein
- Gdp-mannose 4,6-dehydratase / gdp-4-amino-4,6-dideoxy-d-mannose…
- EC
- 2.1.2.-, 4.2.1.47
- Experimental structures
- 8
- Predicted models
- 0
- Ligands
- 8
- Pockets
- 28 · 4 records with a druggable one
Structures
8 records of F8WJP6 in the MolNFT archive: 8 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5VYR | Crystal structure of the WbkC formyl transferase from Brucella melitensis | x-ray diffraction | A, B | B62, CL, GMP | 5 (best 0.77) |
| 5VYR | Crystal structure of the wbkc formyl transferase from brucella melitensis | x-ray diffraction | A, B | B62, CL, GMP | — |
| 5VYS | Crystal structure of the WbkC N-formyltransferase (C47S variant) from Brucella melitensis | x-ray diffraction | A, B | 1YJ, GDP, GMP | 5 (best 0.76) |
| 5VYS | Crystal structure of the wbkc N-formyltransferase (C47S variant) from brucella melitensis | x-ray diffraction | A, B | 1YJ, GDP, GMP | — |
| 5VYT | Crystal structure of the WbkC N-formyltransferase (F142A variant) from Brucella melitensis | x-ray diffraction | A, B, C, D | FON, GDP, CL | 13 (best 0.75) |
| 5VYT | Crystal structure of the wbkc N-formyltransferase (F142A variant) from brucella melitensis | x-ray diffraction | A, B, C, D | FON, GDP, CL | — |
| 5VYU | Crystal structure of the WbkC N-formyltransferase from Brucella melitensis in complex with… | x-ray diffraction | A, B | 1YA, JB2, GDP | 5 (best 0.76) |
| 5VYU | Crystal structure of the wbkc N-formyltransferase from brucella melitensis in complex with… | x-ray diffraction | A, B | 1YA, JB2, GDP | — |
Ligands
- GDP · Guanosine-5'-diphosphate · in 6 records
- CL · Chloride ion · in 4 records
- GMP · Guanosine · in 4 records
- 1YA · N-{4-[{[(6S)-2-amino-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}(formyl)amino]benzoyl}-L-glutamic acid · in 2 records
- 1YJ · N-[4-({[(6R)-2-amino-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid · in 2 records
- B62 · (6R)-2-amino-6-methyl-5,6,7,8-tetrahydropteridin-4(3H)-one · in 2 records
- FON · N-{[4-({[(6R)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]carbonyl}-L-glutamic acid · in 2 records
- JB2 · GDP-perosamine · in 2 records
Elsewhere
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