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Ligand · 1YA

1YA · N-{4-[{[(6S)-2-amino-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}(formyl)amino]benzoyl}-L-glutamic acid

1YA, N-{4-[{[(6S)-2-amino-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}(formyl)amino]benzoyl}-L-glutamic acid (C20 H23 N7 O7, 473.4 g/mol), in the MolNFT structures on GenesisL1: bound in 3 records (2 PDB entries). Every binding site…

Component
1YA
Formula
C20 H23 N7 O7
Class
ligand
Structures
3
PDB entries
2

Binding sites

1YA in 3 structures; the first of them:

  • 5VYU · Crystal structure of the WbkC N-formyltransferase from Brucella melitensis in complex… · 1YA A301 · binds SER84, TYR87, ARG88, SER89, LEU90, ILE91, LEU96, ASN105 and 7 more
  • 5VYU · Crystal structure of the wbkc N-formyltransferase from brucella melitensis in complex… · 1YA A301 · binds SER84, TYR87, ARG88, SER89, LEU90, ILE91, LEU96, ASN105 and 7 more
  • 6EDK · Crystal structure of the formyltransferase psej from anoxybacillus kamchatkensis with… · 1YA A303 · binds TYR74, ARG75, TYR76, ILE77, ILE78, VAL83, ASN92, HIS122 and 9 more

Residues it binds most

ASP 5, LEU 5, ASN 5, SER 5, ARG 5, ILE 5, TYR 5, HIS 5, ALA 4, GLU 4 (residue and the binding sites it lines).

Found with

  • GDP · Guanosine-5'-diphosphate
  • JB2 · GDP-perosamine
  • SO4 · Sulfate ion
  • MES · 2-(N-morpholino)-ethanesulfonic acid

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