UniProt A0R202
ATP synthase subunit alpha (A0R202)
ATP synthase subunit alpha (UniProt A0R202), EC 7.1.2.2: 29 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 116 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- A0R202
- Protein
- ATP synthase subunit alpha
- EC
- 7.1.2.2
- Experimental structures
- 29
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 116 · 9 records with a druggable one
Structures
30 records of A0R202 in the MolNFT archive: 29 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6FOC | F1-ATPase from mycobacterium smegmatis | x-ray diffraction | A, B, C | ADP, MG, PO4 | — |
| 7NJK | Mycobacterium smegmatis ATP synthase state 1A | electron microscopy | A, B, C | ATP, MG, ADP | — |
| 7NJL | Mycobacterium smegmatis ATP synthase state 1b | electron microscopy | A, B, C | ATP, MG, ADP | 17 (best 0.87) |
| 7NJL | Mycobacterium smegmatis ATP synthase state 1B | electron microscopy | A, B, C | ATP, MG, ADP | — |
| 7NJM | Mycobacterium smegmatis ATP synthase state 1C | electron microscopy | A, B, C | ATP, MG, ADP | — |
| 7NJN | Mycobacterium smegmatis ATP synthase state 1D | electron microscopy | A, B, C | ATP, MG, ADP | — |
| 7NJO | Mycobacterium smegmatis ATP synthase state 1e | electron microscopy | A, B, C | ATP, MG, ADP | 17 (best 0.87) |
| 7NJO | Mycobacterium smegmatis ATP synthase state 1E | electron microscopy | A, B, C | ATP, MG, ADP | — |
| 7NJP | Mycobacterium smegmatis ATP synthase state 2 | electron microscopy | A, B, C | ATP, MG, ADP | — |
| 7NJQ | Mycobacterium smegmatis ATP synthase state 3A | electron microscopy | A, B, C | ATP, MG, ADP | — |
| 7NJR | Mycobacterium smegmatis ATP synthase state 3B | electron microscopy | A, B, C | ATP, MG, ADP | — |
| 7NJS | Mycobacterium smegmatis ATP synthase state 3C | electron microscopy | A, B, C | ATP, MG, ADP | — |
| 7NK7 | Mycobacterium smegmatis ATP synthase F1 state 1 | electron microscopy | A, B, C | ATP, MG, ADP | — |
| 7NKB | Mycobacterium smegmatis ATP synthase rotor state 1 | electron microscopy | C | — | — |
| 7NKD | Mycobacterium smegmatis ATP synthase B-delta state 1 | electron microscopy | A, B, C | — | — |
| 7NKH | Mycobacterium smegmatis ATP synthase F1 state 2 | electron microscopy | A, B, C | ATP, MG, ADP | — |
| 7NKJ | Mycobacterium smegmatis ATP synthase F1 state 3 | electron microscopy | A, B, C | ATP, MG, ADP | — |
| 7NKK | Mycobacterium smegmatis ATP synthase rotor state 2 | electron microscopy | C | — | — |
| 7NKL | Mycobacterium smegmatis ATP synthase b-delta state 2 | electron microscopy | A, B, C | — | 4 (best 0.73) |
| 7NKL | Mycobacterium smegmatis ATP synthase B-delta state 2 | electron microscopy | A, B, C | — | — |
| 7NKN | Mycobacterium smegmatis ATP synthase rotor state 3 | electron microscopy | C | — | 1 (best 0.62) |
| 7NKN | Mycobacterium smegmatis ATP synthase rotor state 3 | electron microscopy | C | — | — |
| 7NKQ | Mycobacterium smegmatis ATP synthase B-delta state 3 | electron microscopy | A, B, C | — | — |
| 7NL9 | Mycobacterium smegmatis ATP synthase fo state 3 | electron microscopy | C | — | — |
| 7Y5A | Cryo-EM structure of the Mycolicibacterium smegmatis F1-ATPase | electron microscopy | A, B, C | ATP, MG, ADP | 18 (best 0.89) |
| 7Y5C | Cryo-EM structure of F-ATP synthase from Mycolicibacterium smegmatis (rotational state 2) | electron microscopy | A, B, C | MG, ATP | 16 (best 0.88) |
| 7Y5D | Cryo-EM structure of F-ATP synthase from Mycolicibacterium smegmatis (rotational state 3) (backbone) | electron microscopy | A, B, C | — | 11 (best 0.77) |
| 8G09 | Cryo-EM structure of SQ31f-bound Mycobacterium smegmatis ATP synthase rotational state 2 (backbone… | electron microscopy | A, B, C | ATP, MG | 15 (best 0.80) |
| 8G0A | Cryo-EM structure of SQ31f-bound Mycobacterium smegmatis ATP synthase rotational state 3 | electron microscopy | A, B, C | ATP, MG, PO4 | 17 (best 0.85) |
| A0R202 | AlphaFold monomer V2.0 prediction for ATP synthase subunit alpha (A0R202) | predicted | A | — | — |
Ligands
Experiment against prediction
- 7NKH chain C against the predicted model A0R202: TM-score 0.99, RMSD 0.78 Å
- 6FOC chain C against the predicted model A0R202: TM-score 0.99, RMSD 0.77 Å
- 7NKJ chain C against the predicted model A0R202: TM-score 0.99, RMSD 0.80 Å
- 7NK7 chain C against the predicted model A0R202: TM-score 0.99, RMSD 0.82 Å
- 7NKH chain B against the predicted model A0R202: TM-score 0.99, RMSD 0.90 Å
- 6FOC chain B against the predicted model A0R202: TM-score 0.99, RMSD 0.94 Å
- 7NK7 chain A against the predicted model A0R202: TM-score 0.98, RMSD 1.10 Å
- 7NKJ chain A against the predicted model A0R202: TM-score 0.98, RMSD 1.13 Å
- 7NKH chain A against the predicted model A0R202: TM-score 0.98, RMSD 1.12 Å
- 6FOC chain A against the predicted model A0R202: TM-score 0.98, RMSD 1.17 Å
Elsewhere
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