UniProt A0QUZ2
Hydrolase, NUDIX family protein (A0QUZ2)
Hydrolase, NUDIX family protein (UniProt A0QUZ2): 35 experimental structures on GenesisL1, 16 ligands bound, 54 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- A0QUZ2
- Protein
- Hydrolase, NUDIX family protein
- Experimental structures
- 35
- Predicted models
- 0
- Ligands
- 16
- Pockets
- 54 · 7 records with a druggable one
Structures
35 records of A0QUZ2 in the MolNFT archive: 35 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5GG5 | Crystal structure of Mycobacterium smegmatis MutT1 | x-ray diffraction | A | SO4 | — |
| 5GG5 | Crystal structure of mycobacterium smegmatis MUTT1 | x-ray diffraction | A | — | — |
| 5GG6 | Crystal structure of Mycobacterium smegmatis MutT1 in complex with 8-oxo-dGTP | x-ray diffraction | A, B | 8DG, MG, CL | 8 (best 0.63) |
| 5GG6 | Crystal structure of mycobacterium smegmatis MUTT1 in complex with 8- oxo-dgtp | x-ray diffraction | A, B | — | — |
| 5GG7 | Crystal structure of Mycobacterium smegmatis MutT1 in complex with 8-oxo-dGTP, 8-oxo-dGMP and… | x-ray diffraction | A, B | 8DG, 8OG, POP, MG | 6 (best 0.50) |
| 5GG7 | Crystal structure of mycobacterium smegmatis MUTT1 in complex with 8- oxo-dgtp, 8-oxo-dgmp and… | x-ray diffraction | A, B | — | — |
| 5GG8 | Crystal structure of Mycobacterium smegmatis MutT1 in complex with 8-oxo-dGTP, 8-oxo-dGMP and… | x-ray diffraction | A | 8DG, 8OG, POP, MG | 3 (best 0.51) |
| 5GG8 | Crystal structure of mycobacterium smegmatis MUTT1 in complex with 8- oxo-dgtp, 8-oxo-dgmp and… | x-ray diffraction | A | — | — |
| 5GG9 | Crystal structure of Mycobacterium smegmatis MutT1 in complex with 8-oxo-GTP, 8-oxo-GMP and… | x-ray diffraction | A | 8GT, 8GM, POP, MG | — |
| 5GG9 | Crystal structure of mycobacterium smegmatis MUTT1 in complex with 8- oxo-GTP, 8-oxo-gmp and… | x-ray diffraction | A | — | — |
| 5GGA | Crystal structure of Mycobacterium smegmatis MutT1 in complex with 8-oxo-GDP, 8-oxo-GMP and… | x-ray diffraction | A | G8D, 8GM, POP, MG | 3 (best 0.51) |
| 5GGA | Crystal structure of mycobacterium smegmatis MUTT1 in complex with 8- oxo-GDP, 8-oxo-gmp and… | x-ray diffraction | A | — | — |
| 5GGB | Crystal structure of Mycobacterium smegmatis MutT1 in complex with 8-oxo-dGDP | x-ray diffraction | A | 8GD | 3 (best 0.49) |
| 5GGB | Crystal structure of mycobacterium smegmatis MUTT1 in complex with 8- oxo-dgdp | x-ray diffraction | A | — | — |
| 5GGC | Crystal structure of Mycobacterium smegmatis MutT1 in complex with phosphate and magnesium ions… | x-ray diffraction | A, B | PO4, MG | 5 (best 0.48) |
| 5GGC | Crystal structure of mycobacterium smegmatis MUTT1 in complex with phosphate and magnesium ions… | x-ray diffraction | A, B | — | — |
| 5GGD | Crystal structure of Mycobacterium smegmatis MutT1 in complex with phosphate and magnesium ions… | x-ray diffraction | A, B | PO4, MG | — |
| 5GGD | Crystal structure of mycobacterium smegmatis MUTT1 in complex with phosphate and magnesium ions… | x-ray diffraction | A, B | — | — |
| 5XD1 | Crystal structure of Mycobacterium smegmatis MutT1 in complex with Ap5A, ATP and magnesium | x-ray diffraction | A | 5FA, ATP, MG | 3 (best 0.49) |
| 5XD1 | Crystal structure of mycobacterium smegmatis MUTT1 in complex with AP5A, ATP and magnesium | x-ray diffraction | A | 5FA, ATP, MG | — |
| 5XD2 | Crystal structure of Mycobacterium smegmatis MutT1 in complex with Ap5A, ATP and manganese | x-ray diffraction | A | 5FA, ATP, MN | 3 (best 0.50) |
| 5XD2 | Crystal structure of mycobacterium smegmatis MUTT1 in complex with AP5A, ATP and manganese | x-ray diffraction | A | 5FA, ATP, MN | — |
| 5XD3 | Crystal structure of Mycobacterium smegmatis MutT1 in complex with ATP (I) | x-ray diffraction | A | ATP, MG | 3 (best 0.49) |
| 5XD3 | Crystal structure of mycobacterium smegmatis MUTT1 in complex with ATP (I) | x-ray diffraction | A | ATP, MG | — |
| 5XD4 | Crystal structure of Mycobacterium smegmatis MutT1 in complex with ATP (II) | x-ray diffraction | A | ATP, MG | 3 (best 0.50) |
| 5XD4 | Crystal structure of mycobacterium smegmatis MUTT1 in complex with ATP (II) | x-ray diffraction | A | ATP, MG | — |
| 5XD5 | Crystal structure of Mycobacterium smegmatis MutT1 in complex with ATP, magnesium fluoride and… | x-ray diffraction | B, A | ATP, PO4, MG, F, CL | 8 (best 0.70) |
| 5XD5 | Crystal structure of mycobacterium smegmatis MUTT1 in complex with ATP, magnesium fluoride and… | x-ray diffraction | B, A | ATP, PO4, MG, F, CL | — |
| 6M65 | Crystal structure of mycobacterium smegmatis MUTT1 in complex with gmppnp (GDP) | x-ray diffraction | A | GDP, POP, MG | — |
| 6M69 | Crystal structure of mycobacterium smegmatis MUTT1 in complex with gmppcp (GDP) | x-ray diffraction | A | GDP, POP, MG | — |
| 6M6Y | Crystal structure of Mycobacterium smegmatis MutT1 in complex with 8-oxo-dGTP | x-ray diffraction | A | 8DG, POP, PO4, MG | 3 (best 0.45) |
| 6M6Y | Crystal structure of mycobacterium smegmatis MUTT1 in complex with 8- oxo-dgtp | x-ray diffraction | A | 8DG, POP, PO4, MG | — |
| 6M72 | Crystal structure of Mycobacterium smegmatis MutT1 in complex with 8-oxo-dGDP | x-ray diffraction | A | 8GD, POP, MG | 3 (best 0.49) |
| 6M72 | Crystal structure of mycobacterium smegmatis MUTT1 in complex with 8- oxo-dgdp | x-ray diffraction | A | 8GD, POP, MG | — |
| A0QUZ2 | AlphaFold monomer V2.0 prediction for 8-oxo-(D)GTP phosphatase (A0QUZ2) | — | — | — |
Ligands
- MG · Magnesium ion · in 21 records
- ATP · Adenosine-5'-triphosphate · in 10 records
- POP · Pyrophosphate 2- · in 10 records
- PO4 · Phosphate ion · in 6 records
- 8DG · 8-oxo-2'-deoxyguanosine-5'-triphosphate · in 5 records
- 5FA · Adenosine-5'-pentaphosphate · in 4 records
- 8GD · 2'-deoxy-8-oxoguanosine 5'-(trihydrogen diphosphate) · in 3 records
- CL · Chloride ion · in 3 records
- 8GM · [(2R,3S,4R,5R)-5-[2-azanyl-6,8-bis(oxidanylidene)-1,7-dihydropurin-9-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methyl dihydrogen phosphate · in 2 records
- 8OG · 8-oxo-2'-deoxy-guanosine-5'-monophosphate · in 2 records
- F · Fluoride ion · in 2 records
- GDP · Guanosine-5'-diphosphate · in 2 records
- MN · Manganese (II) ion · in 2 records
- 8GT · 8-oxo-guanosine-5'-triphosphate · in 1 record
- G8D · [(2R,3S,4R,5R)-5-[2-azanyl-6,8-bis(oxidanylidene)-1,7-dihydropurin-9-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methyl phosphono hydrogen phosphate · in 1 record
- SO4 · Sulfate ion · in 1 record
Elsewhere
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