UniProt A0L5S6
Ion transport protein (A0L5S6)
Ion transport protein (UniProt A0L5S6): 57 experimental structures on GenesisL1, 10 ligands bound, 20 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- A0L5S6
- Protein
- Ion transport protein
- Experimental structures
- 57
- Predicted models
- 0
- Ligands
- 10
- Pockets
- 20 · 6 records with a druggable one
Structures
57 records of A0L5S6 in the MolNFT archive: 57 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3ZJZ | Open-form NavMS Sodium Channel Pore (with C-terminal Domain) | x-ray diffraction | A, B, C, D | — | — |
| 3ZJZ | Open-form navms sodium channel pore (with C-terminal domain) | x-ray diffraction | A, B, C, D | — | — |
| 4CBC | Open-form NavMS Sodium Channel Pore (with C-terminal Domain) after thallium soak | x-ray diffraction | A, B, C, D | — | — |
| 4CBC | Open-form navms sodium channel pore (with C-terminal domain) after thallium soak | x-ray diffraction | A, B, C, D | — | — |
| 4F4L | Open Channel Conformation of a Voltage Gated Sodium Channel | x-ray diffraction | A, B, C, D | — | — |
| 4F4L | Open channel conformation of a voltage gated sodium channel | x-ray diffraction | A, B, C, D | — | — |
| 4OXS | Structure of NavMS in complex with channel blocking compound | x-ray diffraction | A, B, C, D | — | — |
| 4OXS | Structure of navms in complex with channel blocking compound | x-ray diffraction | A, B, C, D | — | — |
| 4P2Z | Structure of NavMS T207A/F214A | x-ray diffraction | A, B, C, D | — | — |
| 4P2Z | Structure of navms T207A/F214A | x-ray diffraction | A, B, C, D | — | — |
| 4P30 | Structure of NavMS mutant in presence of PI1 compound | x-ray diffraction | A, B, C, D | — | — |
| 4P30 | Structure of navms mutant in presence of PI1 compound | x-ray diffraction | A, B, C, D | — | — |
| 4P9O | Complex of Voltage-gated ion channel in a the presence of channel blocking compound | x-ray diffraction | A, B, C, D | — | — |
| 4P9O | Complex of voltage-gated ion channel in a the presence of channel blocking compound | x-ray diffraction | A, B, C, D | — | — |
| 4P9P | Structure of NavMS in complex with channel blocking compound | x-ray diffraction | A, B, C, D | — | — |
| 4P9P | Structure of navms in complex with channel blocking compound | x-ray diffraction | A, B, C, D | — | — |
| 4PA3 | Structure of NavMS in complex with channel blocking compound | x-ray diffraction | A, B, C, D | — | — |
| 4PA3 | Structure of navms in complex with channel blocking compound | x-ray diffraction | A, B, C, D | — | — |
| 4PA4 | Structure of NavMS in complex with channel blocking compound | x-ray diffraction | A, B, C, D | — | — |
| 4PA4 | Structure of navms in complex with channel blocking compound | x-ray diffraction | A, B, C, D | — | — |
| 4PA6 | Structure of NavMS pore and C-terminal domain crystallised in the presence of channel blocking… | x-ray diffraction | A, B, C, D | — | — |
| 4PA6 | Structure of navms pore and C-terminal domain crystallised in the presence of channel blocking… | x-ray diffraction | A, B, C, D | — | — |
| 4PA7 | Structure of NavMS pore and C-terminal domain crystallised in presence of channel blocking compound | x-ray diffraction | A, B, C, D | — | — |
| 4PA7 | Structure of navms pore and C-terminal domain crystallised in presence of channel blocking compound | x-ray diffraction | A, B, C, D | — | — |
| 4PA9 | Structure of NavMS in complex with channel blocking compound | x-ray diffraction | A, B, C, D | — | — |
| 4PA9 | Structure of navms in complex with channel blocking compound | x-ray diffraction | A, B, C, D | — | — |
| 4X88 | E178D Selectivity filter mutant of NavMS voltage-gated pore | x-ray diffraction | A, B, C, D | — | — |
| 4X88 | E178D selectivity filter mutant of navms voltage-gated pore | x-ray diffraction | A, B, C, D | — | — |
| 4X89 | NavMs voltage-gated sodium channal pore and C-terminal domain soaked with Silver nitrate | x-ray diffraction | A, B, C, D | — | — |
| 4X89 | Navms voltage-gated sodium channal pore and C-terminal domain soaked with silver nitrate | x-ray diffraction | A, B, C, D | — | — |
| 4X8A | NavMS pore and C-terminal domain grown from protein purified in LiCl | x-ray diffraction | A, B, C, D | — | — |
| 4X8A | Navms pore and C-terminal domain grown from protein purified in licl | x-ray diffraction | A, B, C, D | — | — |
| 5BZB | NavMs voltage-gated sodium channel pore and C-terminal domain | x-ray diffraction | A, B, C, D | — | — |
| 5BZB | Navms voltage-gated sodium channel pore and C-terminal domain | x-ray diffraction | A, B, C, D | — | — |
| 5HVD | Full length Open-form Sodium Channel NavMs I218C | x-ray diffraction | A | 2CV | — |
| 5HVD | Full length open-form sodium channel navms I218C | x-ray diffraction | A | — | — |
| 5HVX | Full length Wild-Type Open-form Sodium Channel NavMs | x-ray diffraction | A | NA, 2CV | 1 (best 0.52) |
| 5HVX | Full length wild-type open-form sodium channel navms | x-ray diffraction | A | — | — |
| 6SX5 | Full length Mutant Open-form Sodium Channel NavMs | x-ray diffraction | A | NA, 2CV | 2 (best 0.52) |
| 6SX5 | Full length mutant open-form sodium channel navms | x-ray diffraction | A | NA, 2CV | — |
| 6SX7 | Crystal Structure of the Voltage-Gated Sodium Channel NavMs (F208L) (2.2 Angstrom resolution) | x-ray diffraction | A | NA, 2CV | 1 (best 0.51) |
| 6SX7 | Crystal structure of the voltage-gated sodium channel navms (F208L) (2.2 ångström resolution) | x-ray diffraction | A | NA, 2CV | — |
| 6SXC | Crystal structure of the Voltage-Gated Sodium Channel NavMs (F208L) in complex with… | x-ray diffraction | A | NA, 2CV, OHT | 1 (best 0.49) |
| 6SXC | Crystal structure of the voltage-gated sodium channel navms (F208L) in complex with… | x-ray diffraction | A | 2CV, OHT | — |
| 6SXE | Crystal Structure of the Voltage-Gated Sodium Channel NavMs (F208L) in complex with Endoxifen (2.6… | x-ray diffraction | A | NA, 2CV, 7PG, 9XY | 2 (best 0.48) |
| 6SXE | Crystal structure of the voltage-gated sodium channel navms (F208L) in complex with endoxifen (2.6… | x-ray diffraction | A | 2CV, 7PG, 9XY | — |
| 6SXF | Crystal Structure of the Voltage-Gated Sodium Channel NavMs (F208L) in complex with Tamoxifen (2.8… | x-ray diffraction | A, B | NA, 2CV, CTX | 4 (best 0.51) |
| 6SXF | Crystal structure of the voltage-gated sodium channel navms (F208L) in complex with tamoxifen (2.8… | x-ray diffraction | A, B | NA, 2CV, CTX | — |
| 6SXG | Crystal Structure of the Voltage-Gated Sodium Channel NavMs in complex with 4-hydroxytamoxifen (2.4… | x-ray diffraction | A | NA, 2CV, OHT | 2 (best 0.50) |
| 6SXG | Crystal structure of the voltage-gated sodium channel navms in complex with 4-hydroxytamoxifen (2.4… | x-ray diffraction | A | 2CV, OHT | — |
| 6YZ0 | Full length Open-form Sodium Channel NavMs F208L in complex with Cannabidiol (CBD) | x-ray diffraction | A | NA, 2CV, CD0 | 2 (best 0.49) |
| 6YZ0 | Full length open-form sodium channel navms F208L in complex with cannabidiol (cbd) | x-ray diffraction | A | NA, 2CV, CD0 | — |
| 6YZ2 | Full length Open-form Sodium Channel NavMs F208L | x-ray diffraction | A | NA, 2CV | 1 (best 0.51) |
| 6YZ2 | Full length open-form sodium channel navms F208L | x-ray diffraction | A | NA, 2CV | — |
| 6Z8C | Crystal Structure of the Voltage-Gated Sodium Channel NavMs (F208L) in complex with… | x-ray diffraction | A | NA, 2CV, QBN | 2 (best 0.51) |
| 6Z8C | Crystal structure of the voltage-gated sodium channel navms (F208L) in complex with… | x-ray diffraction | A | 2CV, QBN | — |
| 8S6J | NavMs in complex with riluzole | x-ray diffraction | A | NA, 657, 2CV, CL | 2 (best 0.49) |
Ligands
- 2CV · Hega-10 · in 21 records
- NA · Sodium ion · in 16 records
- OHT · 4-hydroxytamoxifen · in 4 records
- 7PG · 2,5,8,11,14,17,20,23-octaoxapentacosan-25-ol · in 2 records
- 9XY · Endoxifen · in 2 records
- CD0 · 2-[(1R,2R,5S)-5-methyl-2-(prop-1-en-2-yl)cyclohexyl]-5-pentylbenzene-1,3-diol · in 2 records
- CTX · (Z)-2-[4-(1,2)-diphenyl-1-butenyl)-phenoxy]-N,N-dimethylethanamine · in 2 records
- QBN · 2-[4-[(~{Z})-1,2-diphenylbut-1-enyl]phenoxy]-~{N}-methyl-ethanamine · in 2 records
- 657 · 6-(trifluoromethoxy)-1,3-benzothiazol-2-amine · in 1 record
- CL · Chloride ion · in 1 record
Elsewhere
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