MolNFT v1 · #171269 · protein

Full length open-form sodium channel navms F208L

6YZ2 · Ion transport protein: “Full length open-form sodium channel navms F208L”. X-ray diffraction, 2 ligands (2CV, NA), 1 pocket (best druggability 0.51). MolNFT v1 #171269 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6YZ2
Type: protein
Length: 256 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Ion transport protein
UniProt: A0L5S6
Ligands: 2CV, NA
Pockets: 1 · best druggability 0.51

Structure

x-ray diffraction · 1 distinct chain · 83% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Ion transport protein	protein	256	83% helix, 0% strand	A0L5S6

Ligands and binding sites

2CV · Hega-10 · ligand · 2 copies · chains A
NA · Sodium ion · metal · 3 copies · chains A
12P · Dodecaethylene glycol · additive · 3 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	161	0.51	0.78	19	empty

Compared structures

6YZ2 · Full length Open-form Sodium Channel NavMs F208L · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0L5S6
Elsewhere: RCSB PDB 6YZ2 · PDBe 6YZ2 · UniProt A0L5S6

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