MolNFT v1 · #164425 · protein
Crystal structure of the voltage-gated sodium channel navms (F208L) in complex with tamoxifen (2.8 ångström resolution)
6SXF: “Crystal structure of the voltage-gated sodium channel navms (F208L) in complex with tamoxifen (2.8 ångström…”. X-ray diffraction, 3 ligands (2CV, CTX, NA). MolNFT v1 #164425 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 6SXF
- Type
- protein
- Length
- 526 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- A0L5S6
- Ligands
- 2CV, CTX, NA
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | — | protein | 263 | — | A0L5S6 |
Ligands and binding sites
- 2CV · Hega-10 · ligand · 4 copies · chains A, B
- CTX · (Z)-2-[4-(1,2)-diphenyl-1-butenyl)-phenoxy]-N,N-dimethylethanamine · ligand · 3 copies · chains A, B
- NA · Sodium ion · metal · 6 copies · chains A
- 12P · Dodecaethylene glycol · additive · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6SXF · Crystal Structure of the Voltage-Gated Sodium Channel NavMs (F208L) in complex with… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0L5S6
- Elsewhere: RCSB PDB 6SXF · PDBe 6SXF · UniProt A0L5S6
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