UniProt A0A1U7R319
ATP-binding cassette sub-family C member 8 isoform X2 (A0A1U7R319)
ATP-binding cassette sub-family C member 8 isoform X2 (UniProt A0A1U7R319): 28 experimental structures on GenesisL1, 10 ligands bound, 94 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- A0A1U7R319
- Protein
- ATP-binding cassette sub-family C member 8 isoform X2
- Experimental structures
- 28
- Predicted models
- 0
- Ligands
- 10
- Pockets
- 94 · 6 records with a druggable one
Structures
28 records of A0A1U7R319 in the MolNFT archive: 28 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5YKE | Structure of pancreatic ATP-sensitive potassium channel bound with glibenclamide and ATPgammaS… | electron microscopy | B, D, F, H | GBM | — |
| 5YKE | Structure of pancreatic ATP-sensitive potassium channel bound with glibenclamide and atpgammas… | electron microscopy | B, D, F, H | GBM | — |
| 5YKF | Structure of pancreatic ATP-sensitive potassium channel bound with glibenclamide and ATPgammaS (3D… | electron microscopy | B, D, F, H | GBM, AGS | — |
| 5YKF | Structure of pancreatic ATP-sensitive potassium channel bound with glibenclamide and atpgammas (3D… | electron microscopy | B, D, F, H | GBM, AGS | — |
| 5YKG | Structure of pancreatic ATP-sensitive potassium channel bound with glibenclamide and ATPgammaS… | electron microscopy | B, D, F, H | GBM, AGS | — |
| 5YKG | Structure of pancreatic ATP-sensitive potassium channel bound with glibenclamide and atpgammas… | electron microscopy | B, D, F, H | GBM, AGS | — |
| 5YW7 | Structure of pancreatic ATP-sensitive potassium channel bound with glibenclamide and ATPgammaS… | electron microscopy | B | GBM, AGS | 20 (best 0.82) |
| 5YW7 | Structure of pancreatic ATP-sensitive potassium channel bound with glibenclamide and atpgammas… | electron microscopy | B | GBM, AGS | — |
| 5YW8 | Structure of pancreatic ATP-sensitive potassium channel bound with ATPgammaS (all particles at 4.4A) | electron microscopy | B, D, F, H | AGS | 10 (best 0.83) |
| 5YW8 | Structure of pancreatic ATP-sensitive potassium channel bound with atpgammas (all particles at 4.4A) | electron microscopy | B, D, F, H | AGS | — |
| 5YW9 | Structure of pancreatic ATP-sensitive potassium channel bound with ATPgammaS (class1 5.0A) | electron microscopy | B, D, F, H | AGS | 10 (best 0.83) |
| 5YW9 | Structure of pancreatic ATP-sensitive potassium channel bound with atpgammas (CLASS1 5.0A) | electron microscopy | B, D, F, H | AGS | — |
| 5YWA | Structure of pancreatic ATP-sensitive potassium channel bound with ATPgammaS (CTD class 2 at 6.1A) | electron microscopy | B, D, F, H | AGS | — |
| 5YWA | Structure of pancreatic ATP-sensitive potassium channel bound with atpgammas (ctd class 2 at 6.1A) | electron microscopy | B, D, F, H | AGS | — |
| 5YWB | Structure of pancreatic ATP-sensitive potassium channel bound with Mg-ADP (CTD class2 at 5.2A) | electron microscopy | B, D, F, H | ADP, MG | — |
| 5YWB | Structure of pancreatic ATP-sensitive potassium channel bound with mg- ADP (ctd CLASS2 at 5.2A) | electron microscopy | B, D, F, H | ADP, MG | — |
| 5YWC | Structure of pancreatic ATP-sensitive potassium channel bound with Mg-ADP (CTD class1 at 4.3A) | electron microscopy | B, D, F, H | ADP, MG | — |
| 5YWC | Structure of pancreatic ATP-sensitive potassium channel bound with mg- ADP (ctd CLASS1 at 4.3A) | electron microscopy | B, D, F, H | ADP, MG | — |
| 5YWD | Structure of pancreatic ATP-sensitive potassium channel bound with Mg-ADP (focused refinement of… | electron microscopy | B | ADP, MG | 20 (best 0.84) |
| 5YWD | Structure of pancreatic ATP-sensitive potassium channel bound with mg- ADP (focused refinement of… | electron microscopy | B | ADP, MG | — |
| 6JB1 | Structure of pancreatic ATP-sensitive potassium channel bound with repaglinide and ATPgammaS at… | electron microscopy | B, D, F, H | AGS, AJP, BJX, POV, PTY | — |
| 6JB1 | Structure of pancreatic ATP-sensitive potassium channel bound with repaglinide and atpgammas at… | electron microscopy | B, D, F, H | AGS, AJP, BJX, POV, PTY | — |
| 6JB3 | Structure of SUR1 subunit bound with repaglinide | electron microscopy | B | BJX, AJP | — |
| 6JB3 | Structure of SUR1 subunit bound with repaglinide | electron microscopy | B | BJX, AJP | — |
| 7W4O | The structure of KATP H175K mutant in pre-open state | electron microscopy | B, D, F, H | ADP, MG, E2H, ATP | 19 (best 0.88) |
| 7W4O | The structure of katp H175K mutant in pre-open state | electron microscopy | B, D, F, H | ADP, MG, E2H, ATP | — |
| 7W4P | The structure of KATP H175K mutant in closed state | electron microscopy | B, D, F, H | ADP, MG, E2H, ATP | 15 (best 0.90) |
| 7W4P | The structure of katp H175K mutant in closed state | electron microscopy | B, D, F, H | ADP, MG, E2H, ATP | — |
Ligands
- AGS · Phosphothiophosphoric acid-adenylate ester · in 14 records
- ADP · Adenosine-5'-diphosphate · in 10 records
- MG · Magnesium ion · in 10 records
- GBM · 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl) sulfamoyl]phenyl}ethyl)-2-methoxybenzamide · in 8 records
- AJP · Digitonin · in 4 records
- ATP · Adenosine-5'-triphosphate · in 4 records
- BJX · Repaglinide · in 4 records
- E2H · 6-chloranyl-~{N}-(1-methylcyclopropyl)-1,1-bis(oxidanylidene)-4~{H}-thieno[3,2-E][1,2, 4]thiadiazin-3-amine · in 4 records
- POV · (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate · in 2 records
- PTY · Phosphatidylethanolamine · in 2 records
Elsewhere
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