Ligand · URF
URF · 5-fluorouracil
URF, 5-fluorouracil (C4 H3 F N2 O2, 130.1 g/mol), in the MolNFT structures on GenesisL1: bound in 10 records (8 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with it.
- Component
- URF
- Formula
- C4 H3 F N2 O2
- Class
- ligand
- Structures
- 10
- PDB entries
- 8
Binding sites
URF in 10 structures; the first of them:
- 5IAO · Structure and mapping of spontaneous mutational sites of PyrR from Mycobacterium… · URF A301 · binds ARG58, ASP120, HIS177, VAL178, ARG179
- 6KLK · Crystal structure of the Pseudomonas aeruginosa dihydropyrimidinase complexed with 5-FU · URF A501 · binds HIS61, LEU64, PHE66, KCX150, PHE152, TYR155, HIS183, MET288 and 5 more
- 7D8J · S. aureus SsbB with 5-FU · URF B301 · binds THR12, LYS13, THR30, PHE48
- 7YM1 · Structure of SsbA protein in complex with the anticancer drug 5-fluorouracil · URF A201 · binds ARG18, THR20, PRO21, VAL52, PHE54, GLN78, ARG80, GLU94 and 1 more
- 8GVZ · Crystal structure of the human dihydroorotase domain in complex with the anticancer drug… · URF A1901 · binds HIS1473, ARG1475, ASN1505, KCX1556, THR1562, PHE1563, HIS1590, HIS1614 and 6 more
- 5SXC · Crystal structure of PI3KALPHA in complex with fragment 8 · URF A1101 · binds GLU620, LYS621, LYS656
- 6KLK · Crystal structure of the pseudomonas aeruginosa dihydropyrimidinase complexed with 5-fu · URF A501 · binds HIS61, LEU64, PHE66, KCX150, PHE152, TYR155, HIS183, MET288 and 5 more
- 6L0B · Crystal structure of dihydroorotase in complex with fluorouracil from saccharomyces… · URF A403 · binds HIS16, ARG18, ASN43, KCX98, THR105, THR106, HIS137, LYS230 and 5 more
- 7D8J · S. aureus ssbb with 5-fu · URF B301 · binds THR12, LYS13, THR30, PHE48
- 7DEP · S. aureus ssbb with 5-fu · URF A201 · binds THR12, LYS13, THR30, PHE48, ASN50
Residues it binds most
HIS 10, THR 10, ARG 9, LYS 9, PHE 8, ALA 5, ASP 9, ASN 8, GLY 7, KCX 7 (residue and the binding sites it lines).
Found with
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