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Ligand · 5UD

5UD · 5-fluorouridine

5UD, 5-fluorouridine (C9 H11 F N2 O6, 262.2 g/mol), in the MolNFT structures on GenesisL1: bound in 8 records (4 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with it.

Component
5UD
Formula
C9 H11 F N2 O6
Class
ligand
Structures
8
PDB entries
4

Binding sites

5UD in 8 structures; the first of them:

  • 1RXC · E. COLI uridine phosphorylase: 5-fluorouracil ribose-1-phosphate complex · 5UD J2051 · binds PHE7, HIS8, ARG48, ILE69, ARG91, THR94, THR95, GLY96 and 10 more
  • 1TGV · Structure of E. coli Uridine Phosphorylase complexed with 5-Fluorouridine and sulfate · 5UD A3001 · binds ILE69, ARG91, THR94, THR95, GLY96, PHE162, GLN166, ARG168 and 9 more
  • 4A7S · Structure of human I113T SOD1 mutant complexed with 5-Fluorouridine in the p21 space group · 5UD A1159 · binds GLU21, LYS30, TRP32, SER98
  • 4PB2 · Structure of vcCNT-7C8C bound to 5-fluorouridine · 5UD A501 · binds GLY153, GLN154, GLU156, ALA185, VAL188, TYR192, LEU259, ASN331 and 6 more
  • 1RXC · E. COLI uridine phosphorylase: 5-fluorouracil ribose-1-phosphate complex · 5UD J2051 · binds PHE7, HIS8, ARG48, ILE69, ARG91, THR94, THR95, GLY96 and 10 more
  • 1TGV · Structure of E. COLI uridine phosphorylase complexed with 5- fluorouridine and sulfate · 5UD A3001 · binds ILE69, ARG91, THR94, THR95, GLY96, PHE162, GLN166, ARG168 and 9 more
  • 4A7S · Structure of human I113T SOD1 mutant complexed with 5- fluorouridine in the P21 space… · 5UD A1159 · binds GLU21, LYS30, TRP32, SER98
  • 4PB2 · Structure of vccnt-7C8C bound to 5-fluorouridine · 5UD A501 · binds GLY153, GLN154, GLU156, ALA185, VAL188, TYR192, LEU259, ASN331 and 6 more

Residues it binds most

GLU 12, ARG 6, PHE 8, ILE 8, THR 6, VAL 10, GLN 8, GLY 8, TYR 8, HIS 6 (residue and the binding sites it lines).

Found with

  • K · Potassium ion
  • SO4 · Sulfate ion
  • R1P · 1-O-phosphono-alpha-D-ribofuranose
  • URF · 5-fluorouracil
  • CU · Copper (II) ion
  • NA · Sodium ion
  • ZN · Zinc ion
  • PO4 · Phosphate ion
  • ACT · Acetate ion
  • DMU · Decyl-beta-D-maltopyranoside

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