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Ligand · IHT

IHT · (1~{R})-3,5,5-trimethyl-4-[(3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E},17~{E})-3,7,12,16-tetramethyl-18-(2,6,6-trimethylcyclohexen-1-yl)octadeca-3,5,7,9,11,13,15,17-octaen-1-ynyl]cyclohex-3-en-1-ol

IHT, (1~{R})-3,5,5-trimethyl-4-[(3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E},17~{E})-3,7,12,16-tetramethyl-18-(2,6,6-trimethylcyclohexen-1-yl)octadeca-3,5,7,9,11,13,15,17-octaen-1-ynyl]cyclohex-3-en-1-ol (C40 H54 O, 550.9 g/mol), in the…

Component
IHT
Formula
C40 H54 O
Class
ligand
Structures
5
PDB entries
5

Binding sites

IHT in 5 structures; the first of them:

  • 7Y7B · Cryo-EM structure of cryptophyte photosystem I · IHT 1618 · binds PHE74, THR127, HIS130, ASP131, MET200, ILE201, ILE203, GLY204 and 3 more
  • 7Y8A · Cryo-EM structure of cryptophyte photosystem I · IHT 1618 · binds PHE74, THR127, HIS130, ASP131, MET200, ILE201, ILE203, GLY204 and 3 more
  • 8WB4 · Structure of PSII-ACPII supercomplex from cryptophyte algae · IHT 1618 · binds PHE74, MET127, HIS130, ASN131, ILE202, VAL204, GLY205, VAL208 and 2 more
  • 8XLP · Structure of inactive Photosystem II associated with CAC antenna from Rhodomonas Salina · IHT 2620 · binds PHE68, VAL117, HIS120, ASP121, MET189, ILE190, GLY193, ILE196 and 4 more

Residues it binds most

PHE 48, ILE 42, HIS 44, LEU 40, VAL 31, MET 29, ASP 29, GLY 28, TRP 19, THR 20 (residue and the binding sites it lines).

Found with

  • CLA · Chlorophyll A
  • DGD · Digalactosyl diacyl glycerol (dgdg)
  • II0 · (1~{R})-3,5,5-trimethyl-4-[(3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E})-3,7,12,16-tetramethyl-18-[(4~{R})-2,6,6-trimethyl-4-oxidanyl-cyclohexen-1-yl]octadeca-3,5,7,9,11,13,15-heptaen-1,17-diynyl]cyclohex-3-en-1-ol
  • KC2 · Chlorophyll c2
  • LHG · 1,2-dipalmitoyl-phosphatidyl-glycerole
  • LMG · 1,2-distearoyl-monogalactosyl-diglyceride
  • SQD · 1,2-di-O-acyl-3-O-[6-deoxy-6-sulfo-alpha-D-glucopyranosyl]-sn-glycerol
  • 8CT · (6'R,11cis,11'cis,13cis,15cis)-4',5'-didehydro-5',6'-dihydro-beta,beta-carotene
  • BCT · Bicarbonate ion
  • HEM · Protoporphyrin IX containing Fe
  • II3 · (1~{R})-3,5,5-trimethyl-4-[(3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E},17~{E})-3,7,12,16-tetramethyl-18-[(1~{R},4~{R})-2,6,6-trimethyl-4-oxidanyl-cyclohex-2-en-1-yl]octadeca-3,5,7,9,11,13,15,17-octaen-1-ynyl]cyclohex-3-en-1-ol
  • PHO · Pheophytin A

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