DOC · 2',3'-dideoxycytidine-5'-monophosphate

Binding sites

DOC in 17 structures; the first of them:

• 1KDT · Cytidine monophosphate kinase from E.COLI in complex with 2',3'-dideoxy-cytidine… · DOC A5407 · binds SER14, SER36, GLY37, ALA38, TYR40, ARG41, ARG92, ALA100 and 8 more
• 1Q9X · Crystal structure of Enterobacteria phage RB69 gp43 DNA polymerase complexed with… · DOC I953 · binds DG913, DG914, DC952, TYR619, ASP621, THR622, ASP623, TYR626 and 3 more
• 2VP9 · Structural Studies of Nucleoside Analog and Feedback Inhibitor Binding to Drosophila… · DOC A1211 · binds ILE29, GLU52, TRP57, LEU66, MET69, TYR70, PHE80, GLN81 and 6 more
• 4TQR · Ternary complex of Y-family DNA polymerase Dpo4 with (5'S)-8,5'-Cyclo-2'-deoxyguanosine… · DOC P101 · binds PRO184, GLY185, ILE186, GLY187, DT12, DA3, DG6, DA7
• 4TQS · Ternary complex of Y-family DNA polymerase Dpo4 with (5'S)-8,5'-Cyclo-2'-deoxyguanosine… · DOC C101 · binds ALA102, SER103, ASP105, GLU106, LYS152, GLY185, DA10, DT11 and 3 more
• 4XUS · Crystal structure of the pre-catalytic ternary complex of DNA polymerase lambda with a… · DOC P101 · binds TRP342, LYS472, LEU474, ARG488, ASP490, TYR505, DA5, DA5 and 2 more
• 5C53 · Probing the Structural and Molecular Basis of Nucleotide Selectivity by Human… · DOC P101 · binds ARG853, ASN864, ILE1133, HIS1134, ASP1135, DA5, DT6, DA23
• 6UOM · Y271G DNA polymerase beta ternary complex with templating adenine and incoming r8-oxo-GTP · DOC P101 · binds DA6, DG7, DG9, ASP190, ARG254, ASP256
• 9FM3 · KlenTaq DNA polymerase in a ternary complex with primer/template and a… · DOC B201 · binds ARG573, VAL586, ARG595, ARG660, VAL783, HIS784, ASP785, DA111 and 3 more
• 1KDT · Cytidine monophosphate kinase from E.COLI in complex with 2',3'-dideoxy-cytidine… · DOC A5407 · binds SER14, SER36, GLY37, ALA38, TYR40, ARG41, ARG92, ALA100 and 8 more
• 1Q9X · Crystal structure of enterobacteria phage RB69 GP43 DNA polymerase complexed with… · DOC I953 · binds DG913, DG914, DC952, TYR619, ASP621, THR622, ASP623, TYR626 and 3 more
• 2VP9 · Structural studies of nucleoside analog and feedback inhibitor binding to drosophila… · DOC A1211 · binds ILE29, GLU52, TRP57, LEU66, MET69, TYR70, PHE80, GLN81 and 6 more
• 4TQR · Ternary complex of Y-family DNA polymerase DPO4 with (5'S)-8,5'-cyclo- 2'-deoxyguanosine… · DOC P101 · binds PRO184, GLY185, ILE186, GLY187, DT12, DA3, DG6, DA7
• 4TQS · Ternary complex of Y-family DNA polymerase DPO4 with (5'S)-8,5'-cyclo- 2'-deoxyguanosine… · DOC C101 · binds ALA102, SER103, ASP105, GLU106, LYS152, GLY185, DA10, DT11 and 3 more
• 4XUS · Crystal structure of the pre-catalytic ternary complex of DNA polymerase lambda with a… · DOC P101 · binds TRP342, LYS472, LEU474, ARG488, ASP490, TYR505, DA5, DA5 and 2 more
• 5C53 · Probing the structural and molecular basis of nucleotide selectivity by human… · DOC P101 · binds ARG853, ASN864, ILE1133, HIS1134, ASP1135, DA5, DT6, DA23

Residues it binds most

TYR 30, ARG 27, GLU 20, ASP 23, ALA 24, PHE 16, MET 28, DG 15, VAL 17, DA 13 (residue and the binding sites it lines).

Found with

• MG · Magnesium ion
• TTP · Thymidine-5'-triphosphate
• CA · Calcium ion
• SO4 · Sulfate ion
• 4Y3 · [[(2~{S},5~{R})-5-(4-azanyl-5-fluoranyl-2-oxidanylidene-pyrimidin-1-yl)-1,3$l^{4}-oxathiolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate
• 8GT · 8-oxo-guanosine-5'-triphosphate
• DCP · 2'-deoxycytidine-5'-triphosphate
• DGP · 2'-deoxyguanosine-5'-monophosphate
• MN · Manganese (II) ion
• NA · Sodium ion
• EDO · 1,2-ethanediol
• A1IDZ · [[(2~{R},3~{S},5~{R})-5-[2,4-bis(oxidanylidene)-5-selenophen-2-yl-pyrimidin-1-yl]-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate